Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Siradanahalli C. Guru"'
Autor:
Settara C. Chandrasekharappa, A. Lee Burns, Siradanahalli C. Guru, Karl Y. Bilimoria, Mary Beth Kester, Christina Heppner, Allen M. Spiegel, Sunita K. Agarwal, Stephen J. Marx, Leslie J. Whitty, Francis S. Collins
Publikováno v:
Oncogene. 20:4917-4925
Multiple endocrine neoplasia type 1 is an autosomal dominant tumor syndrome. Manifestations include neoplasms of the parathyroid glands, enteropancreatic neuroendocrine cells, and the anterior pituitary gland. The MEN1 tumor suppressor gene encodes m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::450960d9f5b8dd630a1dfd1815bcb807
https://doi.org/10.1038/sj.onc.1204529
https://doi.org/10.1038/sj.onc.1204529
Autor:
Sunita K. Agarwal, Stephen J. Marx, Eun J. Shin, Jining Lu, Nijaguna B. Prasad, Allen M. Spiegel, Kirugaval Hemavathy, Francis S. Collins, Brian Oliver, Siradanahalli C. Guru, Y. Tony Ip, Settara C. Chandrasekharappa
Publikováno v:
Gene. 263:31-38
Multiple endocrine neoplasia type 1 (MEN1) is a familial cancer syndrome characterized by tumors of the parathyroid, entero-pancreatic neuroendocrine and pituitary tissues and caused by inactivating mutations in the MEN1 gene. Menin, the 610-amino ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c55ce581aacb2a56ce37fda19ff5b8ab
https://doi.org/10.1016/s0378-1119(00)00562-x
https://doi.org/10.1016/s0378-1119(00)00562-x
Publikováno v:
Molecular and Cellular Biology. 20:5087-5095
Snail/Slug family proteins have been identified in diverse species of both vertebrates and invertebrates. The proteins contain four to six zinc fingers and function as DNA-binding transcriptional regulators. Various members of the family have been de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e42cdb70c0d7f1d182f6407d7e46883c
https://doi.org/10.1128/mcb.20.14.5087-5095.2000
https://doi.org/10.1128/mcb.20.14.5087-5095.2000
Autor:
Regina M. Collins, Sunita K. Agarwal, Stephen J. Marx, Siradanahalli C. Guru, Sylvia Y. Park, Suraj Saggar, A. Lee Burns, Michael R. Erdos, Settara C. Chandrasekharappa, Francis S. Collins, Allen M. Spiegel, Christina Heppner
Publikováno v:
Cell. 96:143-152
MEN1 is a tumor suppressor gene that encodes a 610 amino acid nuclear protein (menin) of previously unknown function. Using a yeast two-hybrid screen with menin as the bait, we have identified the transcription factor JunD as a direct menin-interacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfe4bea89131ba207566674c5f034b5d
https://doi.org/10.1016/s0092-8674(00)80967-8
https://doi.org/10.1016/s0092-8674(00)80967-8
Autor:
R. H. Alexander, Allen M. Spiegel, Michael R. Emmert-Buck, Lance A. Liotta, J L Doppman, Irina A. Lubensky, Siradanahalli C. Guru, A L Burns, Larisa V. Debelenko, S E Olufemi, Christina Heppner, Young Sik Kim, Mary Beth Kester, Sunita K. Agarwal, Stephen J. Marx, Z. Zhuang, Settara C. Chandrasekharappa, Monica C. Skarulis, Pachiappan Manickam, Frank H. Collins
Publikováno v:
Journal of Internal Medicine. 243:447-453
Dideoxyfingerprinting was used to screen for germline and somatic MEN1 mutations. This method, applied to a panel of germline DNA from 15 probands with multiple endocrine neoplasia type 1 (MEN-1), allowed confident discovery of the MEN1 gene. Germlin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ff890ef704fa6f648a4c6b326d174bf
https://doi.org/10.1046/j.1365-2796.1998.00348.x
https://doi.org/10.1046/j.1365-2796.1998.00348.x
Autor:
Settara C. Chandrasekharappa, A. Lee Burns, Siradanahalli C. Guru, Stephen J. Marx, Francis S. Collins, Allen M. Spiegel, Paul K. Goldsmith
Publikováno v:
Proceedings of the National Academy of Sciences. 95:1630-1634
The MEN1 gene, mutations in which are responsible for multiple endocrine neoplasia type 1 (MEN1), encodes a 610-amino acid protein, denoted menin. The amino acid sequence of this putative tumor suppressor offers no clue to the function or subcellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e514a6feb3f28a6072ad02df07493715
https://doi.org/10.1073/pnas.95.4.1630
https://doi.org/10.1073/pnas.95.4.1630
Autor:
Shodimu Emmanuel Olufemi, Allen M. Spiegel, Francis S. Collins, Sunita K. Agarwal, Settara C. Chandrasekharappa, Stephen J. Marx, A. Lee Burns, Jane Green, Qihan Dong, Siradanahalli C. Guru, Mary Beth Kester, Pachiappan Manickam
Publikováno v:
Human Mutation. 11:264-269
Familial multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder with affected individuals developing parathyroid, gastrointestinal (GI) endocrine, and anterior pituitary tumors. Four large kindreds from the Burin peninsula/Fortu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7e7af38a19a28642c201bf2a7f14ad6
https://doi.org/10.1002/(sici)1098-1004(1998)11:4<264::aid-humu2>3.0.co
https://doi.org/10.1002/(sici)1098-1004(1998)11:4<264::aid-humu2>3.0.co
Autor:
Shodimu‐Emmanuel Olufemi, Jane S. Green, Pachiappan Manickam, Siradanahalli C. Guru, Sunita K. Agarwal, Mary Beth Kester, Qihan Dong, A. Lee Burns, Allen M. Spiegel, Stephen J. Marx, Francis S. Collins, Settara C. Chandrasekharappa
Publikováno v:
Human Mutation. 11:264-269
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2ac8aff96b102342f272d5c98982e8e
https://doi.org/10.1002/(sici)1098-1004(1998)11:4<264::aid-humu2>3.3.co
https://doi.org/10.1002/(sici)1098-1004(1998)11:4<264::aid-humu2>3.3.co
Autor:
Michael R. Emmert-Buck, Young Sik Kim, Judy S. Crabtree, Francis S. Collins, Pachiappan Manickam, Siradanahalli C. Guru, Sunita K. Agarwal, Mary Beth Kester, Stephen J. Marx, S E Olufemi, Settara C. Chandrasekharappa, Monica C. Skarulis, Lance A. Liotta, Larisa V. Debelenko, Allen M. Spiegel, Christina Heppner, A. Lee Burns, Irina A. Lubensky, Zhengping Zhuang
Publikováno v:
Human Mutation. 12:75-82
Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder that manifests as varying combinations of tumors of endocrine and other tissues (parathyroids, pancreatic islets, duodenal endocrine cells, the anterior pituitary and others
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::946e94ff92bba06e521b07292aa3e4b3
https://doi.org/10.1002/(sici)1098-1004(1998)12:2<75::aid-humu1>3.0.co
https://doi.org/10.1002/(sici)1098-1004(1998)12:2<75::aid-humu1>3.0.co
Autor:
Bruce A. Roe, Mary Beth Kester, Sunita K. Agarwal, Settara C. Chandrasekharappa, S E Olufemi, Stephen J. Marx, Siradanahalli C. Guru, Irina A. Lubensky, Yingping Wang, Pachiappan Manickam, Allen M. Spiegel, Frank H. Collins, Michael R. Emmert-Buck, Jane M. Weisemann, Larisa V. Debelenko, A L Burns, Mark S. Boguski, Lance A. Liotta, Z. Zhuang, Judy S. Crabtree
Publikováno v:
Human Genetics. 101:102-108
Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder in which affected individuals develop tumors primarily in the parathyroids, anterior pituitary, endocrine pancreas, and duodenum. The locus for MEN1 is tightly linked to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc9bb3281bece44ef376c951a15a3832
https://doi.org/10.1007/s004390050595
https://doi.org/10.1007/s004390050595