Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Sir Ian, Wilmut"'
Autor:
Elisabet, Selga, Franziska, Sendfeld, Rebecca, Martinez-Moreno, Claire N, Medine, Olga, Tura-Ceide, Sir Ian, Wilmut, Guillermo J, Pérez, Fabiana S, Scornik, Ramon, Brugada, Nicholas L, Mills
Publikováno v:
Journal of Molecular and Cellular Cardiology
Brugada syndrome predisposes to sudden death due to disruption of normal cardiac ion channel function, yet our understanding of the underlying cellular mechanisms is incomplete. Commonly used heterologous expression models lack many characteristics o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6499a9099d46731260dedb3faebaacfd
https://pubmed.ncbi.nlm.nih.gov/29024690
https://pubmed.ncbi.nlm.nih.gov/29024690
Various cell and tissue types from both embryos and (adult) tissues after birth contain stem cells. Embryonic stem cells, derived from embryos 3 to 5 days after fertilization of an egg in a laboratory test tube, are considered to be pluripotent, wher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::080551d719f0969de7a95185616f8e1f
https://doi.org/10.1016/b978-0-12-381535-4.10005-x
https://doi.org/10.1016/b978-0-12-381535-4.10005-x
Articles on potential therapeutic use of stem cells in the popular press often lack well-defined distinctions between the different stem cell types that could be used, and are sometimes polarized by the ethical debate on the use of embryonic versus a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dea88429643ea6f608341b58fdb7e12c
https://doi.org/10.1016/b978-0-12-381535-4.10007-3
https://doi.org/10.1016/b978-0-12-381535-4.10007-3
Publisher Summary Embryonic development has fascinated scientists and philosophers from ancient culture to the present day. This chapter explores embryonic development. In attempts to unravel the mysteries of embryonic development, a few specific ani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc13ffca0a680c785239ce4269da8183
https://doi.org/10.1016/b978-0-12-381535-4.10002-4
https://doi.org/10.1016/b978-0-12-381535-4.10002-4
This chapter discusses cardiomyocytes from stem cells. If the blood supply to the heart is blocked, cardiac muscle cells (cardiomyocytes) will die because of lack of oxygen. This is called a myocardial infarction. The number of cells that die depends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c3489b3be41340e922f4ec39f1956a9
https://doi.org/10.1016/b978-0-12-381535-4.10008-5
https://doi.org/10.1016/b978-0-12-381535-4.10008-5
This chapter introduces the most important molecular and cell biological principles needed to understand stem cells. Humans and animals, as well as plants and trees, contain many different functional organs and tissues. They are composed of a large v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b951005f38d59225f9e3f0d74de8e826
https://doi.org/10.1016/b978-0-12-381535-4.10001-2
https://doi.org/10.1016/b978-0-12-381535-4.10001-2
Although the idea that cancer stem cells exist and are essential contributors to the aggressive growth of cancer dates back far into the last century, the question of the identity of these cells has proven extremely difficult to answer. Even with the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b365dc9bf7f6f2e16ca29598148ee30
https://doi.org/10.1016/b978-0-12-381535-4.10010-3
https://doi.org/10.1016/b978-0-12-381535-4.10010-3
This chapter explains some of the interesting new ideas currently in development that illustrate the diversity of applications that will be enabled by stem cell technology in the coming few years. The first decade or so of research on stem cells sinc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd1a4ffa82d1fb84a8511744c8f41233
https://doi.org/10.1016/b978-0-12-381535-4.10013-9
https://doi.org/10.1016/b978-0-12-381535-4.10013-9
This chapter discusses stem cell tourism, a term recently coined to describe a growing practice among patients to pay large sums of money to private clinics for often unproven stem cell therapies. Patients can be desperate because conventional medici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f277358d5bd3085e8a7b43283252b815
https://doi.org/10.1016/b978-0-12-381535-4.10009-7
https://doi.org/10.1016/b978-0-12-381535-4.10009-7
Publisher Summary Since a fertilized egg can give rise to a complete new individual, and therefore is totipotent, it had been hypothesized that the cytoplasm of the egg cell contains factors that can reprogram a differentiated cell to the same totipo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae81127c78c079eb1fd3593a769e32ea
https://doi.org/10.1016/b978-0-12-381535-4.10006-1
https://doi.org/10.1016/b978-0-12-381535-4.10006-1