Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Siqin Lei"'
Autor:
Jingwen Deng, Shaoxia Liao, Chaoyi Chen, Fengyan Han, Siqin Lei, Xuan Lai, Kehong Ye, Qizheng Han, Fang E, Chao Lu, Maode Lai, Fanlong Liu, Honghe Zhang
Publikováno v:
Cell Death and Disease, Vol 14, Iss 11, Pp 1-15 (2023)
Abstract Our previous study demonstrated that tumor-suppressor circular RNAs (circRNAs) can be specifically secreted outside of colorectal cancer (CRC) cells within exosomes to maintain tumor cell fitness. However, whether tumor-driving circRNAs can
Externí odkaz:
https://doaj.org/article/ce8f82a4d54b471db7f191f54ec1347e
Autor:
Siqin Lei, Chaoyi Chen, Fengyan Han, Jingwen Deng, Dongdong Huang, Lili Qian, Ming Zhu, Xiaohui Ma, Maode Lai, Enping Xu, Honghe Zhang
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113110- (2023)
Summary: The crosstalk between ferroptosis and cancer metastasis remains unclear. Here, we identify AMER1 as a key regulator of ferroptosis. AMER1 loss causes resistance to ferroptosis in colorectal cancer (CRC) cells. Interestingly, AMER1-deficient
Externí odkaz:
https://doaj.org/article/efe51dd862804c759f06b382eb3958ce
Autor:
Chaoyi Chen, Hongfei Yu, Fengyan Han, Xuan Lai, Kehong Ye, Siqin Lei, Minglang Mai, Maode Lai, Honghe Zhang
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-19 (2022)
Abstract Background & Aims To clarify the biological roles, circularization process and secretion pathway of circRHOBTB3 in colorectal cancer (CRC) progression. Methods We performed a comprehensive analysis of circRNA levels in serum exosomes from mu
Externí odkaz:
https://doaj.org/article/13d98dd752264a3cb3f6103d22446079
Autor:
Jingwen Deng, Dongyi Xian, Xiaopeng Cai, Shaoxia Liao, Siqin Lei, Fengyan Han, Yandong An, Qing He, Guilan Quan, Chuanbin Wu, Tingting Peng, Chao Lu, Honghe Zhang
Publikováno v:
Advanced Functional Materials.
Autor:
Chaoyi Chen, Hongfei Yu, Fengyan Han, Xuan Lai, Kehong Ye, Siqin Lei, Minglang Mai, Maode Lai, Honghe Zhang
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-19 (2022)
Background & Aims To clarify the biological roles, circularization process and secretion pathway of circRHOBTB3 in colorectal cancer (CRC) progression. Methods We performed a comprehensive analysis of circRNA levels in serum exosomes from multiple ty
Autor:
Jiawei Xu, Dajing Xia, Siqin Lei, Maode Lai, Honghe Zhang, Dongdong Huang, Menghan Weng, Yihua Wu, Yuwei Zhou, Enping Xu
Publikováno v:
Clinical nutrition (Edinburgh, Scotland). 39(8)
Summary Background Colorectal cancer (CRC) exhibits a linear progression from normal colonic epithelium, adenoma initiation, carcinoma transformation and even to metastasis. Diet changes might influence carcinogenesis and prognosis. We aimed to deter
Publikováno v:
Pathology - Research and Practice. 216:152775
Background The linear progression from normal colonic epithelium to adenoma initiation, carcinoma transformation and metastasis is considered the classical model of colorectal cancer (CRC) development. Although metformin has been extensively reported