Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Siqi Xiong"'
Autor:
Aimin Li, Haotian Zhou, Siqi Xiong, Junhuai Li, Saurav Mallik, Rong Fei, Yajun Liu, Hongfang Zhou, Xiaofan Wang, Xinhong Hei, Lei Wang
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-10 (2024)
Abstract Background Long non-coding RNAs (lncRNAs) are RNA transcripts of more than 200 nucleotides that do not encode canonical proteins. Their biological structure is similar to messenger RNAs (mRNAs). To distinguish between lncRNA and mRNA transcr
Externí odkaz:
https://doaj.org/article/3842969358e14a56aafe1854bab81fcf
Autor:
Yuqin Liang, Xihao Sun, Hang Chen, Zekai Cui, Jianing Gu, Chunwen Duan, Shengru Mao, Yuexi Chen, Xiaoxue Li, Siqi Xiong, Jiansu Chen
Publikováno v:
Stem Cell Research, Vol 81, Iss , Pp 103581- (2024)
PRPF6, located on chromosome 20, is required for the formation of the spliceosome. Mutations in the PRPF6 gene can lead to retinitis pigmentosa (RP), a common inherited retinal disease characterized by progressive degeneration of retinal pigment epit
Externí odkaz:
https://doaj.org/article/dc87879268074a2e9f7c80185c8dc2f0
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-40 (2023)
Abstract The endoplasmic reticulum (ER) functions as a quality-control organelle for protein homeostasis, or “proteostasis”. The protein quality control systems involve ER-associated degradation, protein chaperons, and autophagy. ER stress is act
Externí odkaz:
https://doaj.org/article/21453beb5c2b4e9d82aed202914f7d21
Publikováno v:
Asian Journal of Surgery, Vol 47, Iss 3, Pp 1544-1545 (2024)
Externí odkaz:
https://doaj.org/article/12845f6b77ff4dd78d8f6de1f37b262b
Publikováno v:
Frontiers in Public Health, Vol 10 (2022)
ObjectivesThe purpose of this study was to explore whether team-based learning (TBL) was more effective than traditional didactic lectures (TDLs) in improving medical students' problem-solving and study skills in the clinical course of ophthalmology.
Externí odkaz:
https://doaj.org/article/fa1ba1d6490a4683a38ff242812616eb
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Skin cutaneous melanoma (SKCM) is a malignant tumor with high mortality rate in human, and its occurrence and development are jointly regulated by genes and the environment. However, the specific pathogenesis of SKCM is not completely understood. In
Externí odkaz:
https://doaj.org/article/f7dcfd2eb584434c825abc10458bec55
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
BackgroundDiabetic retinopathy is a diabetic microvascular complication. Pyroptosis, as a way of inflammatory death, plays an important role in the occurrence and development of diabetic retinopathy, but its underlying mechanism has not been fully el
Externí odkaz:
https://doaj.org/article/6167746fade94f2d9153665c1684e284
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Oxidative stress, mitochondrial impairment, and pathological amyloid beta (Aβ) deposition are involved in the pathogenesis of dry age-related macular degeneration (AMD). The natural flavonoid (–)-epicatechin (EC) is known to be an antioxidant and
Externí odkaz:
https://doaj.org/article/745304b2530f47d48dd82b7a33c88724
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
BackgroundDiabetic retinopathy (DR) is one of the most common microvascular complications of diabetes, which is associated with damage of blood-retinal barrier and ischemia of retinal vasculature. It devastates visual acuity due to leakage of retinal
Externí odkaz:
https://doaj.org/article/9fec7cdec9284c598c14c01379563cea
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Proliferative diabetic retinopathy (PDR), characterized mainly with abnormal epiretinal angiogenesis forming fibrovascular membranes (FVMs), threatens vision of people with diabetes; FVMs consist of extracellular matrix and a variety of cell types in
Externí odkaz:
https://doaj.org/article/78ecefd1546146adb41515aaf167c8e4