Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sippie Huitema"'
Autor:
Wenjiao Zeng, Anke van den Berg, Sippie Huitema, Annette S H Gouw, Grietje Molema, Koert P de Jong
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95826 (2014)
BackgroundHepatocellular carcinoma (HCC) is a classical example of inflammation-linked cancer and is characterized by hypervascularity suggesting rich angiogenesis. Cycloxygenase-2 (COX-2) is a potent mediator of inflammation and is considered to upr
Externí odkaz:
https://doaj.org/article/793eb55b552845a4adb4c6d79aeb4c1f
Autor:
Willem-Peter T. Ruifrok, Sippie Huitema, Harry van Goor, Rudolf A. de Boer, Marian Bulthuis, Anne-Roos S. Frenay
Publikováno v:
Journal of the Renin-Angiotensin-Aldosterone System, Vol 13 (2012)
Journal of the Renin-Angiotensin-Aldosterone System, 13(2), 232-238
Journal of the Renin-Angiotensin-Aldosterone System, 13(2), 232-238
Introduction: Erytropoietin (EPO) has cytoprotective and angiogenic properties and has a beneficial effect in ischaemic conditions. Since the development of renal interstitial abnormalities are often associated with ischaemia, we studied the effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd6a82ad58a61a0b3012b239364e5939
https://doi.org/10.1177/1470320311432186
https://doi.org/10.1177/1470320311432186
Autor:
Marian Bulthuis, Benito A. Yard, Maximilia C. Hottenrott, Johannes Wedel, Jan-Luuk Hillebrands, Sippie Huitema
Publikováno v:
Transplantation, 100(1), 80-90. LIPPINCOTT WILLIAMS & WILKINS
Background Transplant vasculopathy (TV) is a major cause for late graft loss after cardiac transplantation. Endothelial damage and T cell infiltration play a pivotal role in the development of TV. Because N-octanoyl dopamine (NOD) inhibits vascular i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d38c77e1005ef7a50f8deb90a6062358
https://research.rug.nl/en/publications/e0436f56-2833-457e-974c-8230771b1334
https://research.rug.nl/en/publications/e0436f56-2833-457e-974c-8230771b1334
Autor:
Winston W. Bakker, Anke van den Berg, Theo Borghuis, Bernhard Banas, Jola J. Kapojos, Sippie Huitema, Klaas Poelstra
Publikováno v:
European Journal of Pharmacology, 501(1-3), 191-198. ELSEVIER SCIENCE BV
Endothelial as well as mesangial cells show enhanced activity of ecto-apyrase following pro-inflammatory stimulation in vitro. Since this ecto-enzyme appears to be able to regulate plasma hemopexin, which latter molecule plays a role in the pathogene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7c05c960d150acc2b476a7c6fb4c4d0
https://research.rug.nl/en/publications/14305044-bd84-405b-a2eb-6fa2d4092eab
https://research.rug.nl/en/publications/14305044-bd84-405b-a2eb-6fa2d4092eab
Autor:
Martin H. de Borst, Sippie Huitema, Harry van Goor, Gerjan Navis, Rudolf A. de Boer, Lotte M Vis, Wiek H. van Gilst
Publikováno v:
Laboratory Investigation, 83(12), 1761-1770. SPRINGERNATURE
Angiotensin II (AngII) plays an important role in renal damage by acting on hemodynamics, cell-growth, proliferation, and fibrosis, mainly by effects on the AngII type 1 (AT(1)) receptor. The AT(1) receptor activates several intracellular signaling m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35f868ef3e582c48c35facbc23fd1b3a
https://hdl.handle.net/11370/86e32c4a-204c-403c-a4bd-7b8b45428765
https://hdl.handle.net/11370/86e32c4a-204c-403c-a4bd-7b8b45428765
Autor:
Machteld N. Hylkema, Sippie Huitema, Albertus Timmer, Jelmer R. Prins, Marijke M. Faas, Johannes Erwich, Barbro N. Melgert
Publikováno v:
Placenta, 33(5), 453-455. W B SAUNDERS CO LTD
During pregnancy the maternal immune system has to coordinate uterine spiral-artery remodelling, trophoblast invasion, and acceptance of the semi-allogenic fetus simultaneously. As dysregulation of the immune system is associated with adverse pregnan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26889a8dc993c160b7f2b92f0f588d52
https://doi.org/10.1016/j.placenta.2012.02.010
https://doi.org/10.1016/j.placenta.2012.02.010
Autor:
Ben N G Giepmans, Harry van Goor, Wilfred F. A. den Dunnen, Lucas Kuijpers, Madina Baratashvili, Pascale F. Dijkers, Onno Schaap, Milos R. Filipovic, Henri G. D. Leuvenink, Sippie Huitema, Ody C. M. Sibon, Nicola A. Grzeschik, Jan Lj. Miljkovic, Jeroen Kuipers, Harm H. Kampinga, Pauline M. Snijder, Csaba Szabó, Eelke M. Bos, Aleksandra Mitrović
Publikováno v:
Molecular medicine, 21, 758-768. FEINSTEIN INST MED RES
Molecular Medicine
Molecular Medicine
Spinocerebellar ataxia type 3 (SCA3) is a polyglutamine (polyQ) disorder caused by a CAG repeat expansion in the ataxin-3 (ATXN3) gene resulting in toxic protein aggregation. Inflammation and oxidative stress are considered secondary factors contribu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0395df79e95a105e464c2a87429e5857
https://research.rug.nl/en/publications/9f8c4a0c-3dc8-45fb-b049-60a92496155f
https://research.rug.nl/en/publications/9f8c4a0c-3dc8-45fb-b049-60a92496155f
Autor:
Rick Havinga, Sippie Huitema, Han Roelofsen, Annette S. H. Gouw, Folkert Kuipers, Pieter Klok, H. Van Goor, Plm Jansen, TA Vos, Han Moshage
Publikováno v:
Gastroenterology, 113(4), 1323-1333. W.B. Saunders Ltd
BACKGROUND & AIMS: During endotoxemia, expression of inducible nitric oxide synthase (iNOS) and nitric oxide production in the liver is increased. NO has been suggested to have a hepatoprotective function. The aim of this study was to investigate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73c0d5e3a9ef2ca26bf11f3e6919de55
https://doi.org/10.1053/gast.1997.v113.pm9322528
https://doi.org/10.1053/gast.1997.v113.pm9322528
Autor:
Anke van den Berg, Grietje Molema, Sippie Huitema, Wenjiao Zeng, Koert P. de Jong, Annette S. H. Gouw
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95826 (2014)
PLoS ONE, 9(4):e95826. PUBLIC LIBRARY SCIENCE
PLoS ONE
PLoS ONE, 9(4):e95826. PUBLIC LIBRARY SCIENCE
PLoS ONE
Background: Hepatocellular carcinoma (HCC) is a classical example of inflammation-linked cancer and is characterized by hypervascularity suggesting rich angiogenesis. Cycloxygenase-2 (COX-2) is a potent mediator of inflammation and is considered to u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7fc7ebf0c2e243b3f45bec2f8f9fef5
https://doi.org/10.1371/journal.pone.0095826
https://doi.org/10.1371/journal.pone.0095826
Autor:
Barbro N. Melgert, Marijke M. Faas, Sippie Huitema, Gerjan J. Dekkema, Jan Jaap H. M. Erwich, Jelmer R. Prins, Frank E. Dijkstra, Machteld N. Hylkema
Publikováno v:
American Journal of Obstetrics and Gynecology, 207(1):ARTN 76.e1, 76-76. MOSBY-ELSEVIER
OBJECTIVE: During pregnancy the maternal immune system has to adapt its response to accommodate the fetus. The objective of this study was to analyze the effects of smoking on the maternal immune system.STUDY DESIGN: First-trimester decidual tissue a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db62a365f4657070401c5ccac4489442
https://doi.org/10.1016/j.ajog.2012.04.017
https://doi.org/10.1016/j.ajog.2012.04.017