Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Sipho S. Rasehlo"'
Autor:
Daniel M. Muema, Ngomu A. Akilimali, Okechukwu C. Ndumnego, Sipho S. Rasehlo, Raveshni Durgiah, Doty B.A. Ojwach, Nasreen Ismail, Mary Dong, Amber Moodley, Krista L. Dong, Zaza M. Ndhlovu, Jenniffer M. Mabuka, Bruce D. Walker, Jaclyn K. Mann, Thumbi Ndung’u
Publikováno v:
BMC Medicine, Vol 18, Iss 1, Pp 1-17 (2020)
Abstract Introduction Immunological damage in acute HIV infection (AHI) may predispose to detrimental clinical sequela. However, studies on the earliest HIV-induced immunological changes are limited, particularly in sub-Saharan Africa. We assessed th
Externí odkaz:
https://doaj.org/article/12144ae325134e809d1d43e98283a822
Autor:
Daniel M. Muema, Maphe Mthembu, Abigail E. Schiff, Urisha Singh, Björn Corleis, Dongquan Chen, Thierry Bassett, Sipho S. Rasehlo, Kennedy Nyamande, Dilshaad Fakey Khan, Priya Maharaj, Mohammed Mitha, Moosa Suleman, Zoey Mhlane, Taryn Naidoo, Dirhona Ramjit, Farina Karim, Douglas S. Kwon, Thumbi Ndung'u, Emily B. Wong
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The mechanisms by which HIV increases susceptibility to tuberculosis and other respiratory infections are incompletely understood. We used transcriptomics of paired whole bronchoalveolar lavage cells (BLCs) and peripheral blood mononuclear cells to c
Externí odkaz:
https://doaj.org/article/7c55756aceef49838edd3ebe89879c05
Autor:
Okechukwu C. Ndumnego, Doty B.A. Ojwach, Sipho S. Rasehlo, Mary Dong, Nasreen Ismail, Ngomu Akeem Akilimali, Thumbi Ndung'u, Jenniffer M. Mabuka, Raveshni Durgiah, Amber Moodley, Bruce D. Walker, Krista L. Dong, Jaclyn K. Mann, Zaza M. Ndhlovu, Daniel M. Muema
Publikováno v:
BMC Medicine
BMC Medicine, Vol 18, Iss 1, Pp 1-17 (2020)
BMC Medicine, Vol 18, Iss 1, Pp 1-17 (2020)
Introduction Immunological damage in acute HIV infection (AHI) may predispose to detrimental clinical sequela. However, studies on the earliest HIV-induced immunological changes are limited, particularly in sub-Saharan Africa. We assessed the plasma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96caf44ece9c239d0a8890e91c5be99d
http://europepmc.org/articles/PMC7093991
http://europepmc.org/articles/PMC7093991
Autor:
Farina Karim, Dilshaad Fakey Khan, Maphe Mthembu, Thierry Bassett, Mohammed Mitha, Daniel M. Muema, Urisha Singh, Priya Maharaj, Bj□rn Corleis, Moosa Suleman, Thumbi Ndung'u, K Nyamande, Taryn Naidoo, Emily B. Wong, Douglas S. Kwon, Zoey Mhlane, Dirhona Ramjit, Abigail E. Schiff, Sipho S. Rasehlo
The mechanisms by which HIV increases susceptibility to tuberculosis and other respiratory infections are incompletely understood. We used transcriptomics of paired whole bronchoalveolar lavage (BAL) fluid and peripheral blood mononuclear cells to co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6baf3792229b7b6cdd3b7d4d3b042c1
https://doi.org/10.1101/804229
https://doi.org/10.1101/804229
Autor:
Muema, Daniel M., Ngomu A. Akilimali, Okechukwu C. Ndumnego, Sipho S. Rasehlo, Raveshni Durgiah, Doty B.A. Ojwach, Ismail, Nasreen, Dong, Mary, Moodley, Amber, Dong, Krista L., Ndhlovu, Zaza M., Jenniffer M. Mabuka, Walker, Bruce D., Mann, Jaclyn K., Ndung’u, Thumbi
Additional file 2: Supplementary figure 1. Viral load and CD4+ T cell kinetics in participants for whom cytokines were measured. A. Viral loads kinetics in untreated participants (N = 12). B. Viral load kinetics in ART early-treated participants (N =
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37846dcdbe4c70089ec7b5a3aa2b3b57
Autor:
Muema, Daniel M., Ngomu A. Akilimali, Okechukwu C. Ndumnego, Sipho S. Rasehlo, Raveshni Durgiah, Doty B.A. Ojwach, Ismail, Nasreen, Dong, Mary, Moodley, Amber, Dong, Krista L., Ndhlovu, Zaza M., Jenniffer M. Mabuka, Walker, Bruce D., Mann, Jaclyn K., Ndung’u, Thumbi
Additional file 4: Supplementary figure 3. Set point viral loads are inversely associated with set point CD4+ T cell counts in untreated individuals. A. Correlation between peak viral loads and nadir CD4+ T cell counts. B. Correlation between set poi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::961fafc3cfbb1d0801aad728305bdb37
Autor:
Muema, Daniel M., Ngomu A. Akilimali, Okechukwu C. Ndumnego, Sipho S. Rasehlo, Raveshni Durgiah, Doty B.A. Ojwach, Ismail, Nasreen, Dong, Mary, Moodley, Amber, Dong, Krista L., Ndhlovu, Zaza M., Jenniffer M. Mabuka, Walker, Bruce D., Mann, Jaclyn K., Ndung’u, Thumbi
Additional file 2: Supplementary figure 1. Viral load and CD4+ T cell kinetics in participants for whom cytokines were measured. A. Viral loads kinetics in untreated participants (N = 12). B. Viral load kinetics in ART early-treated participants (N =
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca089c57fe7c4dbe2991b2b0b78c5198
Autor:
Muema, Daniel M., Ngomu A. Akilimali, Okechukwu C. Ndumnego, Sipho S. Rasehlo, Raveshni Durgiah, Doty B.A. Ojwach, Ismail, Nasreen, Dong, Mary, Moodley, Amber, Dong, Krista L., Ndhlovu, Zaza M., Jenniffer M. Mabuka, Walker, Bruce D., Mann, Jaclyn K., Ndung’u, Thumbi
Additional file 3: Supplementary figure 2. Presence of attenuating polymorphisms predicts replication capacity of transmitted/founder viruses. A. Similarity of transmitted/founder viruses to the consensus sequence. B. Phylogenetic tree of the transmi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba5de2e32ad194504e021ddbeee35fc8
Autor:
Muema, Daniel M., Ngomu A. Akilimali, Okechukwu C. Ndumnego, Sipho S. Rasehlo, Raveshni Durgiah, Doty B.A. Ojwach, Ismail, Nasreen, Dong, Mary, Moodley, Amber, Dong, Krista L., Ndhlovu, Zaza M., Jenniffer M. Mabuka, Walker, Bruce D., Mann, Jaclyn K., Ndung’u, Thumbi
Additional file 5: Supplementary figure 4. Hyperacute HIV infection is associated with dysregulation of proportions of blood lymphoid and myeloid cells. A. Monocytes percentages. B. Total lymphocytes percentages. C. Eosinophils percentages. D. Basoph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42332ce2df6c389809280fbd9bdd2b66
Autor:
Muema, Daniel M., Ngomu A. Akilimali, Okechukwu C. Ndumnego, Sipho S. Rasehlo, Raveshni Durgiah, Doty B.A. Ojwach, Ismail, Nasreen, Dong, Mary, Moodley, Amber, Dong, Krista L., Ndhlovu, Zaza M., Jenniffer M. Mabuka, Walker, Bruce D., Mann, Jaclyn K., Ndung’u, Thumbi
Additional file 6: Supplementary figure 5. Hyperacute plasma cytokines/chemokines are associated with hematological dysregulations. A. Correlation between interferon gamma and platelets. B. Correlation between IP-10/CXCL10 and neutrophils. C. Correla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::226643d54f007aa18026097e0027b511