Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Sipak Joyasawal"'
Autor:
Swapan Kumar Biswas, Sipak Joyasawal
Publikováno v:
SynOpen, Vol 07, Iss 02, Pp 161-164 (2023)
High-yielding and mild conditions are used to prepare of 1-bromo-2-alkyl- or 2-arylpent-4-en-2-ols/1-bromo-2-alkyl- or 2-arylpent-4-yn-2-ols from α-diazoketones. The reaction involves allylation/propargylation with successive bromide insertion using
Externí odkaz:
https://doaj.org/article/a606d0559b36445b97c08b7f468e8bbe
Publikováno v:
Molecules, Vol 26, Iss 12, p 3520 (2021)
A substituted donor–acceptor cyclobutenecarboxamide is synthesized with modest enantiocontrol through a chiral copper(I) complex catalyzed [3 + 1]-cycloaddition reaction of α-acyl diphenylsulfur ylides with 3-siloxy-2-diazo-3-butenamides. With a m
Externí odkaz:
https://doaj.org/article/bc9b4dae364b4e919a8269862e94eaae
Autor:
Sipak Joyasawal, Swapan Kumar Biswas
Publikováno v:
SynOpen. :161-164
High-yielding and mild conditions are used to prepare of 1-bromo-2-alkyl- or 2-arylpent-4-en-2-ols/1-bromo-2-alkyl- or 2-arylpent-4-yn-2-ols from α-diazoketones. The reaction involves allylation/propargylation with successive bromide insertion using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b552c4adc42cf7a1aa5cd324a8028f18
https://doi.org/10.1055/a-2068-5625
https://doi.org/10.1055/a-2068-5625
Autor:
Keith Long, Zoe Vaughn, Michael David McDaniels, Sipak Joyasawal, Aneta Przepiorski, Emily Parasky, Veronika Sander, David Close, Paul A. Johnston, Alan J. Davidson, Mark de Caestecker, Neil A. Hukriede, Donna M. Huryn
Publikováno v:
ACS Pharmacol Transl Sci
[Image: see text] Acute kidney injury (AKI), a sudden loss of kidney function, is a common and serious condition for which there are no approved specific therapies. While there are multiple approaches to treat the underlying causes of AKI, no targets
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bb62d77d60c78abb1266f29192965aa
https://doi.org/10.1021/acsptsci.1c00243
https://doi.org/10.1021/acsptsci.1c00243
Autor:
Taehee Lee, Forestieri Roberto, Shujuan Xia, M. Grazia Cotticelli, Donna M. Huryn, Robert B. Wilson, Kexin Xu, Amos B. Smith, Sipak Joyasawal
Publikováno v:
ACS Chemical Neuroscience. 11:2535-2542
Friedreich ataxia (FRDA) is an inherited neurodegenerative disorder for which there is no cure or approved treatment. It is characterized by the loss or impaired activity of frataxin protein, which is involved in the biogenesis of iron-sulfur cluster
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b135268c97fbc52d42cc882f5815372b
https://doi.org/10.1021/acschemneuro.0c00323
https://doi.org/10.1021/acschemneuro.0c00323
Publikováno v:
Tetrahedron Letters. 48:5335-5340
A stereoselective synthesis of the ABCD ring framework of azaspiracid-1 and azaspiracid-3 has been achieved using a tandem bis-spiroketalization protocol in the presence of a mild proton source from 1,4-diketone precursor. A tetrahydrofuran intermedi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98808f38b41be7e1e4e7e7afa07868ca
https://doi.org/10.1016/j.tetlet.2007.05.021
https://doi.org/10.1016/j.tetlet.2007.05.021
Publikováno v:
Tetrahedron Letters. 46:7507-7510
A simple and efficient PdCl2/CuCl catalyzed oxidation of alkenes has been successfully developed using a mixture of water and the ionic liquid [bmim][BF4] as solvent. Starting from various types of terminal olefins, the corresponding ketones have bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52cae7b2bacb265ef379823fe2fc46e3
https://doi.org/10.1016/j.tetlet.2005.09.013
https://doi.org/10.1016/j.tetlet.2005.09.013
Publikováno v:
Organic letters. 12(5)
The synthesis of a C1-C19 precursor to pectenotoxin 4 is presented. The strategy employed the functionalized allene shown. Key features include: olefin metathesis of two simple fragments to prepare the left portion of the allene-precursor, diastereos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e02a1bff465f08040bf606091c4e687
https://pubmed.ncbi.nlm.nih.gov/20121257
https://pubmed.ncbi.nlm.nih.gov/20121257
Autor:
Suresh K. Tipparaju, Sipak Joyasawal, Reto Brun, Marco Pieroni, Alan P. Kozikowski, Marcel Kaiser
Publikováno v:
Journal of medicinal chemistry. 51(23)
The first synthesis and biological evaluation of antibiotic 31 (A-33853) and its analogues are reported. Initial screening for inhibition of L. donovani, T. b. rhodesiense, T. cruzi, and P. falciparum cultures followed by determination of IC(50) in L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::756ee80494273dc9061ed55566bcf1e9
https://pubmed.ncbi.nlm.nih.gov/18989953
https://pubmed.ncbi.nlm.nih.gov/18989953
Autor:
Sara Forrester, Alan P. Kozikowski, Debbie C. Mulhearn, Michael E. Johnson, Sipak Joyasawal, Scott D. Pegan, Andrew D. Mesecar, Suresh K. Tipparaju
Publikováno v:
Bioorganicmedicinal chemistry letters. 18(12)
Enoyl-ACP reductase (ENR), the product of the FabI gene, from Bacillus anthracis (BaENR) is responsible for catalyzing the final step of bacterial fatty acid biosynthesis. A number of novel 2-pyridone derivatives were synthesized and shown to be pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0fadef7dfda7d0abcd1d1f8890f1219
https://pubmed.ncbi.nlm.nih.gov/18499454
https://pubmed.ncbi.nlm.nih.gov/18499454