Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Siow Teng Chan"'
Autor:
Quynh Nhu Dinh, Cecilia Lo, David Wong Zhang, Vivian Tran, Tayla Gibson-Hughes, Ashleigh Sheriff, Henry Diep, Hyun Ah Kim, Shenpeng R. Zhang, Liz J. Barreto-Arce, Maria Jelinic, Antony Vinh, Thiruma V. Arumugam, Siow Teng Chan, Rebecca Lim, Grant R. Drummond, Christopher G. Sobey, T. Michael De Silva
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Vascular inflammation and fibrosis are hallmarks of hypertension and contribute to the development of cardiovascular disease and cognitive impairment. However, current anti-hypertensive drugs do not treat the underlying tissue damage, such a
Externí odkaz:
https://doaj.org/article/c612cfe46001495bb86c12c472d59be3
Autor:
Liz J. Barreto-Arce, Hyun Ah Kim, Siow Teng Chan, Rebecca Lim, Grant R. Drummond, Henry Ma, Thanh G. Phan, Christopher G. Sobey, Shenpeng R. Zhang
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
BackgroundThrombolytic agents such as tissue plasminogen activator (tPA) are the only drug class approved to treat ischemic stroke and are usually administered within 4.5 h. However, only ~20% of ischemic stroke patients are eligible to receive the t
Externí odkaz:
https://doaj.org/article/3e2b1adf1f8240659a98ed887f7274db
Autor:
Rebecca Lim, Atul Malhotra, Jean Tan, Siow Teng Chan, Sinnee Lau, Dandan Zhu, Joanne C. Mockler, Euan M. Wallace
Publikováno v:
Stem Cells Translational Medicine, Vol 7, Iss 9, Pp 628-635 (2018)
Abstract Bronchopulmonary dysplasia (BPD) is a chronic lung disease that mainly affects premature babies who require ventilator support. The pathogenesis of BPD is complex but includes vascular maldevelopment, alveolarization arrest, and lung inflamm
Externí odkaz:
https://doaj.org/article/f97fe3b35acd40969e4369b3e05157df
Autor:
Dandan Zhu, Ruth Muljadi, Siow Teng Chan, Patricia Vosdoganes, Camden Lo, Joanne C. Mockler, Euan M. Wallace, Rebecca Lim
Publikováno v:
Stem Cells International, Vol 2016 (2016)
The effects of human amnion epithelial cells (hAECs) on angiogenesis remain controversial. It is yet unknown if the presence of inflammation and/or gestational age of hAEC donors have an impact on angiogenesis. In this study, we examined the differen
Externí odkaz:
https://doaj.org/article/6ccd140af6a948a19df68fec86ee7331
Publikováno v:
Cell Transplantation, Vol 23 (2014)
Human amnion epithelial cells (hAECs) have been shown to modulate inflammation and restore normal lung structure and respiratory function following bleomycin challenge in immune-competent mice. These effects are exerted despite a lack of significant
Externí odkaz:
https://doaj.org/article/c87669dfcb1342c18dfde76ee0f246ba
Autor:
Patricia Vosdoganes, Euan M. Wallace, Siow Teng Chan, Rutu Acharya, Tim J. M. Moss, Rebecca Lim
Publikováno v:
Cell Transplantation, Vol 22 (2013)
With a view to developing a cell therapy for chronic lung disease, human amnion epithelial cells (hAECs) have been shown to prevent acute lung injury. Whether they can repair established lung disease is unknown. We aimed to assess whether hAECs can r
Externí odkaz:
https://doaj.org/article/1b6117e35bae44c0a659b601b49d0785
Autor:
Anqi Li, Mehri Barabadi, Hannah McDonald, Siow Teng Chan, Mirja Krause, Joshua D. Ooi, Gina D. Kusuma, David James, Rebecca Lim
Publikováno v:
Cytotherapy. 24:650-658
Cell viability is an important release criterion in the manufacturing of cell therapy products. Low cell viability can have significant impact on product quality and manufacturing efficiency. Counterflow centrifugation technology has been applied to
Autor:
Renate Schwab, Jean Tan, Mohamed I. Saad, Euan M. Wallace, Dandan Zhu, Siow Teng Chan, Rebecca Lim, Carla F. Kim, Kristen T. Leeman, Gina D. Kusuma
Publikováno v:
Clinical Science. 134:2665-2679
There is a growing appreciation of the role of lung stem/progenitor cells in the development and perpetuation of chronic lung disease including idiopathic pulmonary fibrosis. Human amniotic epithelial cells (hAECs) were previously shown to improve lu
Autor:
David W. Greening, Renate Schwab, Haoyun Fang, Cheng Mee Leong, Gina D. Kusuma, Dandan Zhu, Hannah McDonald, Rebecca Lim, Mehri Barabadi, Euan M. Wallace, Siow Teng Chan
Publikováno v:
ProteomicsREFERENCES. 21(13-14)
The therapeutic properties of cell derived extracellular vesicles (EVs) make them promising cell-free alternative to regenerative medicine. However, clinical translation of this technology relies on the ability to manufacture EVs in a scalable, repro
Autor:
Joanne C. Mockler, Rebecca Lim, Siow Teng Chan, Euan M. Wallace, Sinnee Lau, Atul Malhotra, Jean Tan, Dandan Zhu
Publikováno v:
Stem Cells Translational Medicine, Vol 7, Iss 9, Pp 628-635 (2018)
Stem Cells Translational Medicine
Stem Cells Translational Medicine
Bronchopulmonary dysplasia (BPD) is a chronic lung disease that mainly affects premature babies who require ventilator support. The pathogenesis of BPD is complex but includes vascular maldevelopment, alveolarization arrest, and lung inflammation. Th