Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Siow T, Chan"'
Autor:
Thanh G. Phan, Rebecca Lim, Mirja Krause, Siow T. Chan, Hannah McDonald, Poh-Yi Gan, Shenpeng R. Zhang, Liz J. Barreto Arce, Jason Vuong, Tharani Thirugnanachandran, Benjamin Clissold, John Ly, Shaloo Singhal, Marie Veronic Hervet, Hyun Ah Kim, Grant R. Drummond, Euan M. Wallace, Henry Ma, Christopher G. Sobey
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Externí odkaz:
https://doaj.org/article/b185ea410da94797bd624b9866fc5029
Autor:
Thanh G. Phan, Rebecca Lim, Siow T. Chan, Hannah McDonald, Poh-Yi Gan, Shenpeng R. Zhang, Liz J. Barreto Arce, Jason Vuong, Tharani Thirugnanachandran, Benjamin Clissold, John Ly, Shaloo Singhal, Marie Veronic Hervet, Hyun Ah Kim, Grant R. Drummond, Euan M. Wallace, Henry Ma, Christopher G. Sobey
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
BackgroundWe proposed a Phase I dose escalation trial to assess the safety of allogeneic human amniotic epithelial cells (hAECs) in stroke patients with a view to informing the design for a Phase II trial.MethodsThe design is based on 3 + 3 dose esca
Externí odkaz:
https://doaj.org/article/105c5826d4a14fbf9148d66e304b299e
Autor:
Dandan Zhu, Mirja Krause, Tamara Yawno, Gina D. Kusuma, Renate Schwab, Mehri Barabadi, Amina S. Maleken, Siow T. Chan, Rod Hunt, David Greening, Euan M. Wallace, Rebecca Lim
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-24 (2022)
Abstract Background and rationale Extracellular vesicles (EVs) are a potential cell-free regenerative medicine. Human amniotic epithelial cells (hAECs) are a viable source of cell therapy for diseases like bronchopulmonary dysplasia (BPD). However, l
Externí odkaz:
https://doaj.org/article/eac95c1e88af415daf4554a6f8207a79
Autor:
Dandan Zhu, Jean Tan, Amina S. Maleken, Ruth Muljadi, Siow T. Chan, Sin N. Lau, Kirstin Elgass, Bryan Leaw, Joanne Mockler, Daniel Chambers, Kristen T. Leeman, Carla F. Kim, Euan M. Wallace, Rebecca Lim
Publikováno v:
Stem Cell Research & Therapy, Vol 8, Iss 1, Pp 1-24 (2017)
Abstract Background Despite advances in neonatal care, bronchopulmonary dysplasia (BPD) remains a significant contributor to infant mortality and morbidity. While human amnion epithelial cells (hAECs) have shown promise in small and large animal mode
Externí odkaz:
https://doaj.org/article/493b4a491b494e05afb89c2556933b38
Autor:
Rahana Abd Rahman, Padma Murthi, Rebecca Lim, Bryan Leaw, Euan M. Wallace, Sarah A. Marshall, Annie G. Cox, Joanne C. Mockler, Siow T. Chan, Seshini Gurusinghe
Publikováno v:
Pregnancy Hypertension. 16:1-10
Introduction The maternal endothelial dysfunction characteristic of preeclampsia arises, in part, from excessive placental production of anti-angiogenic factors, including soluble Flt-1, soluble endoglin and activin A, inducing oxidative stress. We a
Autor:
Bryan Leaw, Carla F. Kim, Lois A. Salamonsen, Hong P. T. Nguyen, William Sievert, Mohamed I. Saad, Dandan Zhu, Rebecca Lim, Jean Tan, Siow T. Chan, Sin N. Lau, Euan M. Wallace, Mirja Krause
Publikováno v:
Stem Cells Translational Medicine
Idiopathic pulmonary fibrosis (IPF) is characterized by chronic inflammation, severe scarring, and stem cell senescence. Stem cell‐based therapies modulate inflammatory and fibrogenic pathways by release of soluble factors. Stem cell‐derived extr
Autor:
Siow T. Chan, Sin N. Lau, Euan M. Wallace, Rebecca Lim, Carla F. Kim, Kristen T. Leeman, Ruth Muljadi, Joanne C. Mockler, Daniel C. Chambers, Jean Tan, Dandan Zhu, Bryan Leaw, Kirstin Elgass, Amina S. Maleken
Publikováno v:
Stem Cell Research & Therapy, Vol 8, Iss 1, Pp 1-24 (2017)
Stem Cell Research & Therapy
Stem Cell Research & Therapy
Background Despite advances in neonatal care, bronchopulmonary dysplasia (BPD) remains a significant contributor to infant mortality and morbidity. While human amnion epithelial cells (hAECs) have shown promise in small and large animal models of BPD
Autor:
Yan Z. Tan, Siow T. Chan, Jean Tan, Rebecca Lim, Joanne C. Mockler, Sin N. Lau, Ruth Muljadi, Euan M. Wallace
Publikováno v:
Stem Cells Translational Medicine. 6:1085-1095
Human amnion epithelial cells (hAECs) have been shown to possess potent immunomodulatory properties across a number of disease models. Recently, we reported that hAECs influence macrophage polarization and activity, and that this step was dependent o
Autor:
Bryan Leaw, Annie G. Cox, Euan M. Wallace, Siow T. Chan, Ruth Muljadi, Padma Murthi, Rahana Abd Rahman, Rebecca Lim, Joanne C. Mockler, Harmeet Singh, Seshini Gurusinghe, Sarah A. Marshall
Publikováno v:
Placenta. 60
Introduction Maternal endothelial dysfunction underlying preeclampsia arises from excessive placental release of anti-angiogenic factors, such as soluble fms-like tyrosine kinase-1 (sFlt1), soluble endoglin (sEng) and activin A. Resveratrol, an activ
Autor:
Jean L, Tan, Yan Z, Tan, Ruth, Muljadi, Siow T, Chan, Sin N, Lau, Joanne C, Mockler, Euan M, Wallace, Rebecca, Lim
Publikováno v:
Stem Cells Translational Medicine
Human amnion epithelial cells (hAECs) have been shown to possess potent immunomodulatory properties across a number of disease models. Recently, we reported that hAECs influence macrophage polarization and activity, and that this step was dependent o