Distinct clinical outcomes and biological features of specific KRAS mutants in human pancreatic cancer.

Autor: McIntyre CA; Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Biostatistics and Epidemiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Grimont A; Department of Surgery, Weill Cornell Medicine, New York, NY, USA; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA., Park J; Department of Physiology, Biophysics, and Systems Biology, Weill Cornell Medicine, New York, NY, USA., Meng Y; Department of Surgery, Weill Cornell Medicine, New York, NY, USA; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA; Weill Cornell Graduate School of Medical Sciences, Weill Cornell Medicine, New York, NY, USA., Sisso WJ; Department of Surgery, Weill Cornell Medicine, New York, NY, USA; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA; Weill Cornell Graduate School of Medical Sciences, Weill Cornell Medicine, New York, NY, USA., Seier K; Department of Biostatistics and Epidemiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Jang GH; PanCuRx Translational Research Initiative, Ontario Institute for Cancer Research, Toronto, ON, Canada., Walch H; Marie-Josee and Henry R Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Aveson VG; Department of Surgery, Weill Cornell Medicine, New York, NY, USA; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA., Falvo DJ; Department of Surgery, Weill Cornell Medicine, New York, NY, USA; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA., Fall WB; Department of Surgery, Weill Cornell Medicine, New York, NY, USA; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA; Weill Cornell Graduate School of Medical Sciences, Weill Cornell Medicine, New York, NY, USA., Chan CW; Department of Surgery, Weill Cornell Medicine, New York, NY, USA; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA., Wenger A; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA; Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Ecker BL; Division of Surgical Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA., Pulvirenti A; Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Gelfer R; Weill Cornell Graduate School of Medical Sciences, Weill Cornell Medicine, New York, NY, USA., Zafra MP; Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Schultz N; Marie-Josee and Henry R Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Park W; Gastrointestinal Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; David M. Rubinstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA., O'Reilly EM; Gastrointestinal Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; David M. Rubinstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Houlihan SL; Caryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA., Alonso A; Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Hissong E; Department of Pathology, Weill Cornell Medicine, New York, NY, USA., Church GM; Department of Genetics, Harvard Medical School, Boston, MA, USA., Mason CE; Department of Physiology, Biophysics, and Systems Biology, Weill Cornell Medicine, New York, NY, USA; WorldQuant Initiative for Quantitative Prediction, Weill Cornell Medicine, New York, NY, USA., Siolas D; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA; Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Notta F; PanCuRx Translational Research Initiative, Ontario Institute for Cancer Research, Toronto, ON, Canada., Gonen M; Department of Biostatistics and Epidemiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Dow LE; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA; Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Jarnagin WR; Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA; David M. Rubinstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Chandwani R; Department of Surgery, Weill Cornell Medicine, New York, NY, USA; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA; David M. Rubinstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Cell and Developmental Biology, Weill Cornell Medicine, New York, NY, USA. Electronic address: roc9045@med.cornell.edu.

Publikováno v: Cancer cell [Cancer Cell] 2024 Sep 09; Vol. 42 (9), pp. 1614-1629.e5. Date of Electronic Publication: 2024 Aug 29.

Neoadjuvant botensilimab plus balstilimab response pattern in locally advanced mismatch repair proficient colorectal cancer.

Autor: Kasi PM; Department of Oncology/Hematology, New York Presbyterian/Weill Cornell Medicine New York, New York, NY, 10021, USA. pmk4001@med.cornell.edu., Hidalgo M; Department of Oncology/Hematology, New York Presbyterian/Weill Cornell Medicine New York, New York, NY, 10021, USA., Jafari MD; Department of Surgery, New York Presbyterian/Weill Cornell Medicine New York, New York, NY, 10021, USA., Yeo H; Department of Surgery, New York Presbyterian/Weill Cornell Medicine New York, New York, NY, 10021, USA.; Department of Population Health Sciences, Weill Cornell Medicine, New York, NY, 10021, USA., Lowenfeld L; Department of Surgery, New York Presbyterian/Weill Cornell Medicine New York, New York, NY, 10021, USA., Khan U; Department of Oncology/Hematology, New York Presbyterian/Weill Cornell Medicine New York, New York, NY, 10021, USA., Nguyen ATH; Department of Oncology/Hematology, New York Presbyterian/Weill Cornell Medicine New York, New York, NY, 10021, USA., Siolas D; Department of Oncology/Hematology, New York Presbyterian/Weill Cornell Medicine New York, New York, NY, 10021, USA., Swed B; Department of Oncology/Hematology, New York Presbyterian/Weill Cornell Medicine New York, New York, NY, 10021, USA., Hyun J; Department of Oncology/Hematology, New York Presbyterian/Weill Cornell Medicine New York, New York, NY, 10021, USA., Khan S; Department of Oncology/Hematology, New York Presbyterian/Weill Cornell Medicine New York, New York, NY, 10021, USA., Wood M; Department of Oncology/Hematology, New York Presbyterian/Weill Cornell Medicine New York, New York, NY, 10021, USA., Samstein B; Department of Surgery, New York Presbyterian/Weill Cornell Medicine New York, New York, NY, 10021, USA., Rocca JP; Department of Surgery, New York Presbyterian/Weill Cornell Medicine New York, New York, NY, 10021, USA., Ocean AJ; Department of Oncology/Hematology, New York Presbyterian/Weill Cornell Medicine New York, New York, NY, 10021, USA., Popa EC; Department of Oncology/Hematology, New York Presbyterian/Weill Cornell Medicine New York, New York, NY, 10021, USA., Hunt DH; Department of Surgery, New York Presbyterian/Weill Cornell Medicine New York, New York, NY, 10021, USA., Uppal NP; Department of Oncology/Hematology, New York Presbyterian/Weill Cornell Medicine New York, New York, NY, 10021, USA., Garrett KA; Department of Surgery, New York Presbyterian/Weill Cornell Medicine New York, New York, NY, 10021, USA., Pigazzi A; Department of Surgery, New York Presbyterian/Weill Cornell Medicine New York, New York, NY, 10021, USA., Zhou XK; Department of Population Health Sciences, Weill Cornell Medicine, New York, NY, 10021, USA., Shah MA; Department of Oncology/Hematology, New York Presbyterian/Weill Cornell Medicine New York, New York, NY, 10021, USA., Hissong E; Department of Pathology and Laboratory Medicine, New York Presbyterian/Weill Cornell Medicine, New York, NY, 10021, USA.

Publikováno v: Oncogene [Oncogene] 2023 Oct; Vol. 42 (44), pp. 3252-3259. Date of Electronic Publication: 2023 Sep 21.

Corrigendum: Tumor infiltrating T cell states and checkpoint inhibitor expression in hepatic and pancreatic malignancies.

Autor: Wan S; Department of Surgery, NYU Langone Health, New York, NY, United States., Zhao E; Department of Surgery, NYU Langone Health, New York, NY, United States.; Perlmutter Cancer Center, NYU Langone Health, New York, NY, United States., Freeman D; Pathology, NYU Langone Health, New York, NY, United States., Weissinger D; Perlmutter Cancer Center, NYU Langone Health, New York, NY, United States., Krantz BA; Perlmutter Cancer Center, NYU Langone Health, New York, NY, United States.; Internal Medicine, NYU Langone Health, New York, NY, United States., Werba G; Perlmutter Cancer Center, NYU Langone Health, New York, NY, United States., Khanna LG; Internal Medicine, NYU Langone Health, New York, NY, United States., Siolas D; Perlmutter Cancer Center, NYU Langone Health, New York, NY, United States.; Internal Medicine, NYU Langone Health, New York, NY, United States., Oberstein PE; Perlmutter Cancer Center, NYU Langone Health, New York, NY, United States.; Internal Medicine, NYU Langone Health, New York, NY, United States., Chattopadhyay PK; Perlmutter Cancer Center, NYU Langone Health, New York, NY, United States.; Pathology, NYU Langone Health, New York, NY, United States.; Talon Biomarkers, Mendham, NJ, United States., Simeone DM; Department of Surgery, NYU Langone Health, New York, NY, United States.; Perlmutter Cancer Center, NYU Langone Health, New York, NY, United States.; Pathology, NYU Langone Health, New York, NY, United States., Welling TH; Department of Surgery, NYU Langone Health, New York, NY, United States.; Perlmutter Cancer Center, NYU Langone Health, New York, NY, United States.

Publikováno v: Frontiers in immunology [Front Immunol] 2023 Mar 23; Vol. 14, pp. 1177713. Date of Electronic Publication: 2023 Mar 23 (Print Publication: 2023).

Papillary Dermal Elastolysis Secondary to Combination Nivolumab and Cabiralizumab Therapy: Histiocytes and Dermal Mucin as Clues to the Diagnosis.

Autor: Yin L; The Ronald O. Perelman Department of Dermatology, New York University Grossman School of Medicine, New York, NY; and., Criscito MC; The Ronald O. Perelman Department of Dermatology, New York University Grossman School of Medicine, New York, NY; and., Stokar E; The Ronald O. Perelman Department of Dermatology, New York University Grossman School of Medicine, New York, NY; and., Siolas D; Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY., Haimovic A; The Ronald O. Perelman Department of Dermatology, New York University Grossman School of Medicine, New York, NY; and., Lo Sicco K; The Ronald O. Perelman Department of Dermatology, New York University Grossman School of Medicine, New York, NY; and., Brinster NK; The Ronald O. Perelman Department of Dermatology, New York University Grossman School of Medicine, New York, NY; and.

Publikováno v: The American Journal of dermatopathology [Am J Dermatopathol] 2021 Oct 01; Vol. 43 (10), pp. 746-749.

Tumor-microenvironment-on-a-chip: the construction and application.

Autor: Xu, Hanzheng^1,2 (AUTHOR), Wen, Jiangtao³ (AUTHOR), Yang, Jiahua¹ (AUTHOR), Zhou, Shufen^1,2 (AUTHOR), Li, Yijie¹ (AUTHOR), Xu, Ke^4,5 (AUTHOR) kexu@shu.edu.cn, Li, Wei¹ (AUTHOR) liwei1511972@163.com, Li, Sen¹ (AUTHOR) lee_lisen@163.com

Publikováno v: Cell Communication & Signaling. 10/23/2024, Vol. 22 Issue 1, p1-22. 22p.