Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Siobhan McCormick"'
Autor:
Vesna Sossi, Joseph R. Patterson, Siobhan McCormick, Christopher J. Kemp, Kathryn M. Miller, Anna C. Stoll, Nathan Kuhn, Michael Kubik, Joseph Kochmanski, Kelvin C. Luk, Caryl E. Sortwell
Publikováno v:
Movement Disorders. 37:1739-1748
Positron emission tomography (PET) imaging in early Parkinson's disease (PD) subjects reveals that increased dopamine (DA) turnover and reduced dopamine transporter (DAT) density precede decreases in DA synthesis and storage. The rat α-synuclein pre
Autor:
Noeen, Malik, Rick, Kornelsen, Siobhan, McCormick, Nadine, Colpo, Helen, Merkens, Shreya, Bendre, Francois, Benard, Vesna, Sossi, Ralf, Schirrmacher, Paul, Schaffer
Publikováno v:
European journal of medicinal chemistry. 211
Among all genetic mutations of LRRK2, the G2019S mutation is the most commonly associated with the late-onset of Parkinson's disease (PD). Hence, one potential therapeutic approach is to block the hyperactivity of mutated LRRK2 induced by kinase inhi
Autor:
Matthew A. Sacheli, Carolyn English, Danielle K. Murray, Nicole Neilson, Elham Shahinfard, Jessamyn McKenzie, Martin J. McKeown, Vesna Sossi, Bimal Lakhani, A. Jon Stoessl, Lara A. Boyd, Katie Dinelle, Michael Schulzer, Donald C. McKenzie, Nasim Vafai, Silke Appel-Cresswell, Siobhan McCormick, Jason L. Neva
Publikováno v:
Movement disorders : official journal of the Movement Disorder SocietyReferences. 34(12)
Background The objective of this study was to examine the effects of aerobic exercise on evoked dopamine release and activity of the ventral striatum using positron emission tomography and functional magnetic resonance imaging in Parkinson's disease
Autor:
Paul Schaffer, Vesna Sossi, Francois Benard, Nadine Colpo, Rick Kornelsen, Ralf Schirrmacher, Helen Merkens, Siobhan McCormick, Noeen Malik, Shreya Bendre
Publikováno v:
European Journal of Medicinal Chemistry. 211:113005
Purpose Among all genetic mutations of LRRK2, the G2019S mutation is the most commonly associated with the late-onset of Parkinson’s disease (PD). Hence, one potential therapeutic approach is to block the hyperactivity of mutated LRRK2 induced by k
Autor:
Michael J. Adam, Jessie Fanglu Fu, Mariya V. Cherkasova, Jason Valerio, Elham Shahinfard, Jing Zhang, Shu-Ying Liu, Siobhan McCormick, Nasim Vafai, Daryl Wile, Martin J. McKeown, Thomas J. Ruth, Vesna Sossi, Zbigniew K. Wszolek, Julieta E. Arena, Alexandra Perez-Soriano, Rostom Mabrouk, Cyrus P. Zabetian, Nicole Neilson, Jess McKenzie, Jan O. Aasly, Michael Schulzer, Piu Chan, A. Jon Stoessl
Publikováno v:
The Lancet. Neurology. 17(4)
Summary Background Markers of neuroinflammation are increased in some patients with LRRK2 Parkinson's disease compared with individuals with idiopathic Parkinson's disease, suggesting possible differences in disease pathogenesis. Previous PET studies
Autor:
Carles Vilariño-Güell, Vanessa Silva, A. Jon Stoessl, Christopher A. Robinson, Christina Thompson, Vesna Sossi, Silke Appel-Cresswell, Jessamyn McKenzie, Siobhan McCormick, Alex Rajput, Dennis W. Dickson, Katherine Dinelle, Ali H. Rajput, Matthew J. Farrer
Publikováno v:
Movement Disorders. 29:1684-1687
Background Families of Dutch-German-Russian Mennonite descent with multi-incident parkinsonism have been identified as harboring a pathogenic DNAJC13 p.N855S mutation and are awaiting clinical and pathophysiological characterization. Methods Family m
Autor:
Siobhan McCormick, A. Jon Stoessl, Matthew J. Farrer, James E. Holden, Vesna Sossi, Katherine Dinelle, Chenoa Mah, Matthew D. Walker, Rick Kornelsen
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 33:59-66
Longitudinal measurements of dopamine (DA) uptake and turnover in transgenic rodents may be critical when developing disease-modifying therapies for Parkinson's disease (PD). We demonstrate methodology for such measurements using [18F]fluoro-3,4-dihy
Autor:
Donald B. Calne, A. Jon Stoessl, Lisa Kuramoto, Raúl de la Fuente-Fernández, Chong S. Lee, Siobhan McCormick, Jacquelyn J. Cragg, Wing Lok Au, Edwin Mak, Vesna Sossi, Jess McKenzie, Michael Schulzer, Thomas J. Ruth, Nandhagopal Ramachandiran
Publikováno v:
Annals of Neurology. 69:803-810
Objective: To investigate in vivo the impact of age on nigrostriatal dopamine dysfunction in Parkinson's disease (PD). Methods: PD patients (n = 78) and healthy control subjects (n = 35) underwent longitudinal positron emission tomography assessments
Autor:
Richard Ting, Siobhan McCormick, Michael J. Adam, Thomas J. Ruth, Curtis W. Harwig, Pamela Austin, David M. Perrin, Ulrich auf dem Keller, Christopher M. Overall
Publikováno v:
Journal of the American Chemical Society. 130:12045-12055
The use of a boronic ester as a captor of aqueous [(18)F]-fluoride has been previously suggested as a means of labeling biomolecules in one step for positron emission tomography (PET) imaging. For this approach to be seriously considered, the [(18)F]
Autor:
James E. Holden, A. Jon Stoessl, Siobhan McCormick, Matthew D. Walker, Matthew J. Farrer, Katherine Dinelle, Chenoa Mah, Rick Kornelsen, Anna Lee, Vesna Sossi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53f98d1df507048f437a4dbd09f46e5d
https://doi.org/10.1016/b978-0-12-800044-1.00144-6
https://doi.org/10.1016/b978-0-12-800044-1.00144-6