Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Siobhan I. Davis"'
Publikováno v:
BMJ military health. 166(6)
Disease non-battle injury has plagued British expeditionary forces through the ages. While in recent years significant mortality has reduced, it has had a large impact on operational effectiveness, at times leading to closure of major medical treatme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4edd3beeccd20ea825ee1126e872a5bf
https://pubmed.ncbi.nlm.nih.gov/33293376
https://pubmed.ncbi.nlm.nih.gov/33293376
Autor:
Harika Boztepe, Siobhan I. Davis, Kenneth E. White, Fatemehsadat Esteghamat, Refik Tanakol, Seyed Mohammad Javad Mortazavi, Mahdi Malekpour, Holly J. Garringer
Publikováno v:
American Journal of Medical Genetics Part A. :2390-2396
Familial tumoral calcinosis (TC) is characterized by elevated serum phosphate concentrations, normal or elevated 1,25(OH)2 vitamin D, as well as periarticular and vascular calcifications. Recessive mutations in the mucin-like glycosyltransferase GalN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d910faf28823c3d3c99dd7bde8e45b4
https://doi.org/10.1002/ajmg.a.31947
https://doi.org/10.1002/ajmg.a.31947
Autor:
Shubin Zhang, Marc K. Drezner, Shiguang Liu, Yongbo Lu, Frank Rauch, Baozhi Yuan, Siobhan I. Davis, Hector F. Rios, Leanne M Ward, Lynda F. Bonewald, Jian Q. Feng, Xijie Yu, L. Darryl Quarles, Yixia Xie, Kenneth E. White
Publikováno v:
Nature Genetics. 38:1310-1315
The osteocyte, a terminally differentiated cell comprising 90%–95% of all bone cells1,2, may have multiple functions, including acting as a mechanosensor in bone (re)modeling3. Dentin matrix protein 1 (encoded by DMP1) is highly expressed in osteoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74b0382bb86419141413254225a06bff
https://doi.org/10.1038/ng1905
https://doi.org/10.1038/ng1905
Autor:
Bhaskar Dasgupta, Mohamad S. Draman, Holly J. Garringer, Daniel L. Koller, Niamh Conlon, Siobhan I. Davis, Neal S. Fedarko, Alka Jain, Kenneth E. White, Corinne Fisher, M. J. Cullen, Tobias E. Larsson
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 91:4037-4042
Context: Familial tumoral calcinosis (TC) results from disruptions in phosphate metabolism and is characterized by high serum phosphate with normal or elevated 1,25 dihydroxyvitamin vitamin D concentrations and ectopic and vascular calcifications. Re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7165ee0ba93fb3e73e08ac53ff0f872c
https://doi.org/10.1210/jc.2006-0305
https://doi.org/10.1210/jc.2006-0305
Autor:
Siobhan I. Davis, Fuming Zhang, Moosa Mohammadi, Regina Goetz, Kenneth E. White, Xijie Yu, David M. Ornitz, Omar A. Ibrahimi, Robert J. Linhardt, Holly J. Garringer
Publikováno v:
Endocrinology. 146:4647-4656
Fibroblast growth factor (FGF)-23 has emerged as an endocrine regulator of phosphate and of vitamin D metabolism. It is produced in bone and, unlike other FGFs, circulates in the bloodstream to ultimately regulate phosphate handling and vitamin D pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25801b7304e0c4ebd001a7605579a2d6
https://doi.org/10.1210/en.2005-0670
https://doi.org/10.1210/en.2005-0670
Publikováno v:
ResearcherID
Fibroblast growth factor-23 (FGF23) is a circulating factor that plays critical roles in phosphate and vitamin D metabolism. The goal of our studies was to dissect the pathways directing the vitamin D-phosphate-FGF23 homeostatic axis. To test the rol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7ad3a5012dafbe34b328539269f27d2
https://doi.org/10.1016/j.bone.2005.03.002
https://doi.org/10.1016/j.bone.2005.03.002
Autor:
Siobhan I. Davis, Tobias E. Larsson, Xijie Yu, Mohamad S. Draman, M. J. Cullen, Kenneth E. White, Sean D. Mooney
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 90:2424-2427
Gain-of-function mutations in fibroblast growth factor-23 (FGF23) are responsible for autosomal dominant hypophosphatemic rickets, a disorder of isolated renal phosphate wasting. Patients with the disorder display hypophosphatemia with normocalcemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a079a938083f3ee45f1a3c505479a077
https://doi.org/10.1210/jc.2004-2238
https://doi.org/10.1210/jc.2004-2238
Autor:
Leo Mascarenhas, Emily G. Farrow, Pisit Pitukcheewanont, Yvonne Gutierrez, Peter Beighton, Siobhan I. Davis, Sean D. Mooney, Kenneth E. White
Publikováno v:
American Journal of Medical Genetics Part A. :537-539
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9983124935d926d085a0905081a907d
https://doi.org/10.1002/ajmg.a.31106
https://doi.org/10.1002/ajmg.a.31106
Publikováno v:
Journal of the American Society of Nephrology : JASN. 20(5)
Fibroblast growth factor-23 (FGF23), a hormone central to phosphate and vitamin D metabolism, reduces renal absorption of phosphate by downregulating the sodium-phosphate cotransporter Npt2a. However, the mechanisms of FGF23 action in the kidney are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a8bd7d1bda26c731b88b8959791b706
https://pubmed.ncbi.nlm.nih.gov/19357251
https://pubmed.ncbi.nlm.nih.gov/19357251
Autor:
Emily G. Farrow, Mahdi Malekpour, Dan E. Arking, Kenneth E. White, Fatemehsadat Esteghamat, Seyed Mohammad Javad Mortazavi, Xijie Yu, Holly J. Garringer, Siobhan I. Davis, Harry C. Dietz
Publikováno v:
American journal of physiology. Endocrinology and metabolism. 295(4)
Fibroblast growth factor 23 (FGF23) is a hormone required for normal renal phosphate reabsorption. FGF23 gain-of-function mutations result in autosomal dominant hypophosphatemic rickets (ADHR), and FGF23 loss-of-function mutations cause familial hype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f55c05835d106c38e5117bc2cf6fc171
https://pubmed.ncbi.nlm.nih.gov/18682534
https://pubmed.ncbi.nlm.nih.gov/18682534