Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Sinoeun Touch"'
Autor:
Aimin Tang, Zhifeng Chen, Kara S. Cox, Hua-Poo Su, Cheryl Callahan, Arthur Fridman, Lan Zhang, Sangita B. Patel, Pedro J. Cejas, Ryan Swoyer, Sinoeun Touch, Michael P. Citron, Dhanasekaran Govindarajan, Bin Luo, Michael Eddins, John C. Reid, Stephen M. Soisson, Jennifer Galli, Dai Wang, Zhiyun Wen, Gwendolyn J. Heidecker, Danilo R. Casimiro, Daniel J. DiStefano, Kalpit A. Vora
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Respiratory syncytial virus (RSV) is a leading cause of infant hospitalization. Here, the authors isolate a human monoclonal antibody that binds to a highly conserved epitope on the RSV fusion protein, neutralizes RSV A and B subtypes equipotently an
Externí odkaz:
https://doaj.org/article/353ee58e3241465cbd5aae22b7984ad3
Autor:
Hualin Li, Cheryl Callahan, Michael Citron, Zhiyun Wen, Sinoeun Touch, Morgan A Monslow, Kara S Cox, Daniel J DiStefano, Kalpit A Vora, Andrew Bett, Amy Espeseth
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0187642 (2017)
Respiratory syncytial virus (RSV) is a leading cause of serious lower respiratory tract disease in young children and older adults throughout the world. Prevention of severe RSV disease through active immunization is optimal but no RSV vaccine has be
Externí odkaz:
https://doaj.org/article/e018d3e0e3ee41dbb4b9118e502bda6f
Autor:
Jessica A, Flynn, Teresa, Weber, Pedro J, Cejas, Kara S, Cox, Sinoeun, Touch, Lauren A, Austin, Yangsi, Ou, Michael P, Citron, Bin, Luo, Marian E, Gindy, Kapil, Bahl, Giuseppe, Ciaramella, Amy S, Espeseth, Lan, Zhang
Publikováno v:
Vaccine. 40:4412-4423
In response to immune pressure, influenza viruses evolve, producing drifted variants capable of escaping immune recognition. One strategy for inducing a broad-spectrum immune response capable of recognizing multiple antigenically diverse strains is t
Autor:
Bob J. Lucas, Deborah D. Nahas, Sinoeun Touch, Jinfu Xie, Kalpit A. Vora, Robin M. Kaufhold, Melissa A. Boddicker, Julie M. Skinner, Kara S. Cox, Amy S. Espeseth
Publikováno v:
World Journal of Vaccines. 10:55-75
We evaluated novel Chlamydial vaccines, consisting of major outer membrane protein (MOMP) alone or in combination with polymorphic membrane proteins D (PmpD) and G (PmpG) using a C57BL/6 mouse model. Native MOMP (nMOMP) isolated from C. muridarum ele
Autor:
Michael P. Citron, Zhiyun Wen, Nickita Mehta, Galit Alter, Amy S. Espeseth, Daniel J. DiStefano, Jishnu Das, Sinoeun Touch, Cheryl Callahan, Jeffrey R. Sachs, Tomer Zohar, Paloma Cejas, Andrew J. Bett, Anush Devadhasan, Douglas A. Lauffenburger, Wiktor Karpinski
Publikováno v:
SSRN Electronic Journal.
Respiratory syncytial virus (RSV) infection is a major cause of severe respiratory illness in both young infants and the elderly. While antibodies represent key correlates of protection, the antibody mechanisms remain poorly understood. Emerging data
Autor:
Tomer Zohar, Jeff C. Hsiao, Nickita Mehta, Jishnu Das, Anush Devadhasan, Wiktor Karpinski, Cheryl Callahan, Michael P. Citron, Daniel J. DiStefano, Sinoeun Touch, Zhiyun Wen, Jeffrey R. Sachs, Pedro J. Cejas, Amy S. Espeseth, Douglas A. Lauffenburger, Andrew J. Bett, Galit Alter
Publikováno v:
Cell Host & Microbe. 30:41-52.e5
Respiratory syncytial virus (RSV) infection is a major cause of respiratory illness in infants and the elderly. Although several vaccines have been developed, none have succeeded in part due to our incomplete understanding of the correlates of immune
Autor:
Andrew J. Bett, Dai Wang, Zhiyun Wen, Andrew H. Latham, Lan Zhang, Kalpit A. Vora, Michael P. Citron, Jeffrey S. Smith, Marian E. Gindy, Christine A. Shaw, Joseph M. Antonello, Jessica A. Flynn, Ryan Swoyer, Cheryl Callahan, Giuseppe Ciaramella, Paloma Cejas, Daniel J. DiStefano, Kapil Bahl, Daniel C. Freed, Kara S. Cox, Gregory O’ Donnell, Amy S. Espeseth, Sinoeun Touch, Jennifer D. Galli, Daria J. Hazuda
Publikováno v:
NPJ Vaccines
npj Vaccines, Vol 5, Iss 1, Pp 1-14 (2020)
npj Vaccines, Vol 5, Iss 1, Pp 1-14 (2020)
The RSV Fusion (F) protein is a target for neutralizing antibody responses and is a focus for vaccine discovery; however, the process of RSV entry requires F to adopt a metastable prefusion form and transition to a more stable postfusion form, which
Autor:
Sinoeun Touch, Chinedu G. Orekie, Cameron M. Douglas, Walter Knapp, Jane Fontenot, Amy S. Espeseth, Zhiyun Wen, Michael P. Citron, Ioan Petrescu, Mona Purcell, Cheryl Callahan, Xiaoping Liang, Sai Prasanth Chamarthy, Manishkumar Patel, Paul McQuade, Daniel Rubins, Shu-An Lin, Alexa Gleason, Matthew Pine
Publikováno v:
Vaccine. 36:2876-2885
Respiratory syncytial virus (RSV) is the most common viral cause of bronchiolitis and pneumonia in children twelve months of age or younger and a significant cause of lower respiratory disease in older adults. As various clinical and preclinical cand
Autor:
Paloma Cejas, Paul Parmet, Amy S. Espeseth, Arthur Fridman, Jennifer D. Galli, Scott Cosmi, Lan Zhang, Sinoeun Touch, Andrew J. Bett, Bin Luo, Eberhard Durr
Publikováno v:
Vaccine. 36(52)
Respiratory Syncytial Virus (RSV) infection is the leading cause of lower respiratory tract infection in both young children and older adults. Currently, there is no licensed vaccine available, and therapeutic options are limited. The infectious RSV