Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Sinno H P, Simons"'
Autor:
Jarinda A. Poppe, Robert B. Flint, Anne Smits, Sten P. Willemsen, Kelly K. Storm, Debbie H. Nuytemans, Wes Onland, Marten J. Poley, Willem P. de Boode, Katherine Carkeek, Vincent Cassart, Luc Cornette, Peter H. Dijk, Marieke A. C. Hemels, Isabelle Hermans, Matthias C. Hütten, Dorottya Kelen, Ellen H. M. de Kort, André A. Kroon, Julie Lefevere, Katleen Plaskie, Breanne Stewart, Michiel Voeten, Mirjam M. van Weissenbruch, Olivia Williams, Inge A. Zonnenberg, Thierry Lacaze-Masmonteil, Arjan B.te Pas, Irwin K. M. Reiss, Anton H. van Kaam, Karel Allegaert, G. Jeroen Hutten, Sinno H. P. Simons
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-13 (2023)
Abstract Background Apnoea of prematurity (AOP) is one of the most common diagnoses among preterm infants. AOP often leads to hypoxemia and bradycardia which are associated with an increased risk of death or disability. In addition to caffeine therap
Externí odkaz:
https://doaj.org/article/1beb5ecbe5d64793b43c02fe04d5f72b
Publikováno v:
Children, Vol 11, Iss 9, p 1102 (2024)
Similar to other populations, care of neonates strongly relies on robust guidance on neonatal pharmacotherapy, covering an age-appropriate drug formulation, an individualized dose, and information on its efficacy and safety for a specific indication
Externí odkaz:
https://doaj.org/article/17ec53265cfa4338acf3f4b4dbcbd1bd
Autor:
Serife Kurul, H. Rob Taal, Robert B. Flint, Jan Mazela, Irwin K. M. Reiss, Karel Allegaert, Sinno H. P. Simons
Publikováno v:
BMC Pediatrics, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background Late onset sepsis is a leading cause of death and morbidity in preterm infants. Despite optimal antibiotic treatment, sepsis related mortality and morbidity is still high. Pentoxifylline (PTX) is a methylxanthine with promising im
Externí odkaz:
https://doaj.org/article/04f096fd61b94ec28099d40747b9f4db
Autor:
Şerife Kurul, Sinno H. P. Simons, Christian R. B. Ramakers, Yolanda B. De Rijke, René F. Kornelisse, Irwin K. M. Reiss, H. Rob Taal
Publikováno v:
Critical Care, Vol 25, Iss 1, Pp 1-10 (2021)
Abstract Background Sepsis is a major health issue in preterm infants. Biomarkers are used to diagnose and monitor patients with sepsis, but C-reactive protein (CRP) is proven not predictive at onset of late onset neonatal sepsis (LONS) diagnosis. Th
Externí odkaz:
https://doaj.org/article/7a38c7a6f7224c9b82e5566ecee17450
Autor:
Şerife Kurul, BSc, Sinno H. P. Simons, MD, PhD, Christian R. B. Ramakers, PhD, Yolanda B. De Rijke, PhD, René F. Kornelisse, MD, PhD, André A. Kroon, MD, PhD, Irwin K. M. Reiss, MD, PhD, H. Rob Taal, MD, PhD
Publikováno v:
Critical Care Explorations, Vol 3, Iss 12, p e0585 (2021)
BACKGROUND:. Late-onset neonatal sepsis is a major complication in preterm neonates. Early identification of the type of infection could help to improve therapy and outcome depending on the suspected microorganism by tailoring antibiotic treatment to
Externí odkaz:
https://doaj.org/article/ac7f412ba39f4d85ade7dc75bf4f0acc
Autor:
Fleur M. Keij, Bjørn E. V. Koch, Fernando Lozano Vigario, Sinno H. P. Simons, Johan G. C. van Hasselt, H. Rob Taal, C. A. J. Knibbe, Herman P. Spaink, Irwin K. M. Reiss, Elke H. J. Krekels
Publikováno v:
Journal of Clinical and Translational Science, Vol 5 (2021)
Neonatal sepsis is a major cause of death and disability in newborns. Commonly used biomarkers for diagnosis and evaluation of treatment response lack sufficient sensitivity or specificity. Additionally, new targets to treat the dysregulated immune r
Externí odkaz:
https://doaj.org/article/9924878bb4804dca8344c5a48b18b1e4
Autor:
Liron Borenstein-Levin, Jarinda A. Poppe, Willem van Weteringen, H. Rob Taal, Ori Hochwald, Amir Kugelman, Irwin K. M. Reiss, Sinno H. P. Simons
Publikováno v:
Pediatric Research, 93(4), 932-937. Lippincott Williams & Wilkins
Background: An oxygen saturation (SpO2) histogram classification system has been shown to enable quantification of SpO2 instability into five types, based on histogram distribution and time spent at SpO2 ≤ 80%. We aimed to investigate this classifi
Autor:
Johan C. A. de Klerk, Aline G. J. Engbers, Floor van Beek, Robert B. Flint, Irwin K. M. Reiss, Swantje Völler, Sinno H. P. Simons
Publikováno v:
Frontiers in Pediatrics, Vol 8 (2020)
The optimal management strategy for patent ductus arteriosus in preterm infants remains a topic of debate. Available evidence for a treatment strategy might be biased by the delayed spontaneous closure of the ductus arteriosus in preterm infants, whi
Externí odkaz:
https://doaj.org/article/f85004a4f15d4332ba261ee1c338e432
Autor:
Jarinda A. Poppe, Willem van Weteringen, Lotte L. G. Sebek, Catherijne A. J. Knibbe, Irwin K. M. Reiss, Sinno H. P. Simons, Robert B. Flint
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
IntroductionCurrent drug dosing in preterm infants is standardized, mostly based on bodyweight. Still, covariates such as gestational and postnatal age may importantly alter pharmacokinetics and pharmacodynamics. Evaluation of drug therapy in these p
Externí odkaz:
https://doaj.org/article/f525a90ecfda4204acf4664cab0f03d3
Autor:
Emilie Hitzerd, Igna F. Reijnders, Annemarie G. M. G. J. Mulders, Anton H. J. Koning, Irwin K. M. Reiss, A. H. Jan Danser, Régine P. M. Steegers-Theunissen, Sinno H. P. Simons, Maria P. H. Koster
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
ObjectiveTo explore the correlation between in vivo placental volumetric parameters in the first trimester of pregnancy and ex vivo parameters of fetoplacental vascular function after delivery.MethodsIn ten singleton physiological pregnancies, placen
Externí odkaz:
https://doaj.org/article/7883fe5fde004de6a2ddc6032d2e34e7