Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Sinifunanya E. Nwaobi"'
Autor:
Sinifunanya E. Nwaobi, Andrew Charles, Shrayes Raman, Dmitri N. Yousef Yengej, Guido C. Faas, Isabella Ferando, Gayane Kechechyan
Publikováno v:
The Journal of Physiology. 599:4545-4559
A minimally invasive, microchip-based approach enables continuous long-term recording of brain neurovascular activity, heart rate, and head movement in freely behaving rodents. This approach can also be used for transcranial optical triggering of cor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5f0c6626e0625d065cce8f07cbc6f2c
https://doi.org/10.1113/jp281514
https://doi.org/10.1113/jp281514
Publikováno v:
Glia
Kir4.1, a glial-specific inwardly rectifying potassium channel, is implicated in astrocytic maintenance of K+ homeostasis. Underscoring the role of Kir4.1 in central nervous system (CNS) functioning, genetic mutations in KCNJ10, the gene which encode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::655cdc5ada96497f3d277e17dfb87d95
https://doi.org/10.1002/glia.23797
https://doi.org/10.1002/glia.23797
Publikováno v:
HeadacheREFERENCES. 61(10)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a52be2abe5f681e6113fd99dc2ef19b
https://pubmed.ncbi.nlm.nih.gov/34806166
https://pubmed.ncbi.nlm.nih.gov/34806166
Autor:
Sinifunanya E. Nwaobi, Joshua Kamins
Publikováno v:
JAMA Network Open. 4:e2114788
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::baa5ce4aacc88c53103ccefff59bf0cf
https://doi.org/10.1001/jamanetworkopen.2021.14788
https://doi.org/10.1001/jamanetworkopen.2021.14788
Autor:
Kelsey C. Patterson, Michelle L. Olsen, Sinifunanya E. Nwaobi, Vishnu Anand Cuddapah, Anita C. Randolph
Publikováno v:
Acta Neuropathologica. 132:1-21
Kir4.1 is an inwardly rectifying K(+) channel expressed exclusively in glial cells in the central nervous system. In glia, Kir4.1 is implicated in several functions which include extracellular K(+) homeostasis, maintenance of astrocyte resting membra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc4f3d4414b0a364b5bbd56fa8ee24ce
https://doi.org/10.1007/s00401-016-1553-1
https://doi.org/10.1007/s00401-016-1553-1
Publikováno v:
Degenerative Neurological and Neuromuscular Disease
Rett syndrome (RTT), an X-linked neurodevelopment disorder, occurs in approximately one out of 10,000 females. Individuals afflicted by RTT display a constellation of signs and symptoms, affecting nearly every organ system. Most striking are the neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a112d212c00e42263dd609ce75ce6f9
http://europepmc.org/articles/PMC7337177
http://europepmc.org/articles/PMC7337177
Publikováno v:
Glia. 62:411-427
Kir4.1, a glial-specific K+ channel, is critical for normal CNS development. Studies using both global and glial-specific knockout of Kir4.1 reveal abnormal CNS development with the loss of the channel. Specifically, Kir4.1 knockout animals are chara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b8b3eb3763e76a49545f8283d37bc96
https://doi.org/10.1002/glia.22613
https://doi.org/10.1002/glia.22613
Publikováno v:
Journal of visualized experiments : JoVE. (103)
DNA methylation serves to regulate gene expression through the covalent attachment of a methyl group onto the C5 position of a cytosine in a cytosine-guanine dinucleotide. While DNA methylation provides long-lasting and stable changes in gene express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9fe15f6ca9239a9af7ecc0eee883bf79
https://pubmed.ncbi.nlm.nih.gov/26436772
https://pubmed.ncbi.nlm.nih.gov/26436772
Publikováno v:
Journal of Visualized Experiments.
DNA methylation serves to regulate gene expression through the covalent attachment of a methyl group onto the C5 position of a cytosine in a cytosine-guanine dinucleotide. While DNA methylation provides long-lasting and stable changes in gene express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6403dacff438ce58727f6dfc2d75396d
https://doi.org/10.3791/52406
https://doi.org/10.3791/52406
Autor:
Baljit S. Khakh, Michael V. Sofroniew, Xiaoping Tong, Ji Xu, Yan Ao, Mark Anderson, Michelle L. Olsen, Martin D. Haustein, Guido C. Faas, Istvan Mody, Sinifunanya E. Nwaobi
Publikováno v:
Nature neuroscience
Nature neuroscience, vol 17, iss 5
Nature neuroscience, vol 17, iss 5
Huntington's disease (HD) is characterized by striatal medium spiny neuron (MSN) dysfunction, but the underlying mechanisms remain unclear. We explored roles for astrocytes, in which mutant huntingtin is expressed in HD patients and mouse models. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76743a7df00a832b44ba9c074cc2bc08
https://pubmed.ncbi.nlm.nih.gov/24883452
https://pubmed.ncbi.nlm.nih.gov/24883452