Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Sinibaldo Romero Arocha"'
Autor:
Puspa Thapa, Sinibaldo Romero Arocha, Ji Young Chung, Derek B. Sant’Angelo, Virginia Smith Shapiro
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract NKT cells are a distinct subset that have developmental requirements that often differ from conventional T cells. Here, we show that NKT-specific deletion of Hdac3 results in a severe reduction in the number of iNKT cells, particularly of NK
Externí odkaz:
https://doaj.org/article/bb0b26a9f24f4d3983eb28ce34699aa4
Autor:
Maura Shramko, Lauren McPherson, Miranda Harris, Maggie Plattes, Sinibaldo Romero Arocha, Sally Jeon, Maria Veronica Svetaz
Publikováno v:
Journal of Adolescent Health. 72:S105-S106
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2f100976c9588192b62b7a089498bc2
https://doi.org/10.1016/j.jadohealth.2022.11.212
https://doi.org/10.1016/j.jadohealth.2022.11.212
Autor:
Mark Li, Zeji Du, Timothy E. Peterson, Amy L. Lightner, Ao Shi, Atta Behfar, Sinibaldo Romero Arocha
Publikováno v:
Crohn's & Colitis 360. 1
Background Clinical trials utilizing mesenchymal stem cells (MCSs) for the treatment of perianal Crohn disease are expanding. Most enrolled Crohn patients are being actively treated with corticosteroids, immunomodulators, and biologic therapy for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::379c4bf6096853ee37ff2a75981e4114
https://doi.org/10.1093/crocol/otz025
https://doi.org/10.1093/crocol/otz025
Autor:
Aaron D. Schwab, Virginia Smith Shapiro, Shaylene A. McCue, Sinibaldo Romero Arocha, Barsha Dash, Matthew J. Rajcula, Ji Young Chung, Puspa Thapa, Michael J. Shapiro
Publikováno v:
Immunohorizons
NKAP and HDAC3 are critical for T cell maturation. NKAP and HDAC3 physically associate, and a point mutation in NKAP, NKAP(Y352A), abrogates this interaction. To evaluate the significance of NKAP and HDAC3 association in T cell maturation, transgenic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04baf5c13f82c2567fc5f56a146e379e
https://europepmc.org/articles/PMC7409817/
https://europepmc.org/articles/PMC7409817/
Autor:
Aaron D. Schwab, Pritha Chanana, Rachael L. Philips, Sinibaldo Romero Arocha, Ji Young Chung, Virginia Smith Shapiro, Jeong Heon Lee, Tamas Ordog, Krutika S. Gaonkar
Publikováno v:
eLife, Vol 8 (2019)
CD4 and CD8 T cells are vital components of the immune system. We found that histone deacetylase 3 (HDAC3) is critical for the development of CD4 T cells, as HDAC3-deficient DP thymocytes generate only CD8SP thymocytes in mice. In the absence of HDAC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e9c16869a375b79344efb638f530143
https://elifesciences.org/articles/43821
https://elifesciences.org/articles/43821
Autor:
Rachael L. Philips, Virginia Smith Shapiro, Aaron D. Schwab, Pritha Chanana, Ji Young Chung, Sinibaldo Romero Arocha, Krutika S. Gaonkar, Tamas Ordog, Jeong Heon Lee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c275bc31d6796eedec40babeeddc789
https://doi.org/10.7554/elife.43821.038
https://doi.org/10.7554/elife.43821.038
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edcecaaac09e53a233a1eb753b93d6d0
https://doi.org/10.1096/fasebj.2020.34.s1.02946
https://doi.org/10.1096/fasebj.2020.34.s1.02946
Autor:
Virginia Smith Shapiro, Sinibaldo Romero Arocha, Michael J. Shapiro, Michael Jonathan Lehrke, Ji Young Chung
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 202(8)
NKAP is a multifunctional nuclear protein that associates with the histone deacetylase HDAC3. Although both NKAP and HDAC3 are critical for hematopoietic stem cell (HSC) maintenance and survival, it was not known whether these two proteins work toget
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ea7ba83cdbc65608ecdf51a970f3a43
https://pubmed.ncbi.nlm.nih.gov/30804042
https://pubmed.ncbi.nlm.nih.gov/30804042
Autor:
Ji Young Chung, Virginia Smith Shapiro, Puspa Thapa, Sinibaldo Romero Arocha, Derek B. Sant'Angelo
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports
Scientific Reports
NKT cells are a distinct subset that have developmental requirements that often differ from conventional T cells. Here, we show that NKT-specific deletion of Hdac3 results in a severe reduction in the number of iNKT cells, particularly of NKT1 cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edec1d27f802090cc4d6a07b0cc2b965
https://doi.org/10.1038/s41598-017-06102-5
https://doi.org/10.1038/s41598-017-06102-5
Autor:
Chien Chang Chen, Megan M. Constans, Meibo W. Chen, Virginia Smith Shapiro, Paul J. Belmonte, Ji Young Chung, Sinibaldo Romero Arocha, Michael J. Shapiro, Barsha Dash, Fan Chi Hsu, Douglas C. McWilliams
Publikováno v:
Scientific Reports
The transcription factor Runx1 has essential roles throughout hematopoiesis. Here, we demonstrate that Runx1 is critical for T cell maturation. Peripheral naïve CD4+ T cells from CD4-cre Runx1 cKO mice are phenotypically and functionally immature as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d86180b98bf5b28c28c3cc0f5f59c167