Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Sini Sunny"'
Autor:
Arun Jyothidasan, Sini Sunny, Asokan Devarajan, Aniqa Sayed, John Kofi Afortude, Brian Dalley, Vivek Nanda, Steven Pogwizd, Silvio H. Litovsky, Joel D. Trinity, Matthew Might, Namakkal S. Rajasekaran
Publikováno v:
Redox Biology, Vol 75, Iss , Pp 103263- (2024)
The endoplasmic reticulum (ER) regulates protein folding and maintains proteostasis in cells. We observed that the ER transcriptome is impaired during chronic reductive stress (RS) in cardiomyocytes. Here, we hypothesized that a prolonged moderate tr
Externí odkaz:
https://doaj.org/article/89d8b21237c04432b90821ae7822b5b0
Autor:
S. Mohd. Shiraz Rizvi, Sini Sunny, Irshad A. Wani, Farzana Mahdi, Zeeshan H. Zaidi, Namakkal S. Rajasekaran
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Assessing regional wall motion abnormalities (RWMA) in the myocardium may provide early diagnosis and treat chronic remodeling in STEMI patients. We assessed RWMA in 217 subjects with anterior STEMI admitted to Era University Hospital in Lucknow, UP,
Externí odkaz:
https://doaj.org/article/00584dadaf5a4c6eb9cd5d858605004d
Autor:
Chae‐Myeong Ha, Sayan Bakshi, Manoja K. Brahma, Luke A. Potter, Samuel F. Chang, Zhihuan Sun, Gloria A. Benavides, Lihao He, Prachi Umbarkar, Luyun Zou, Samuel Curfman, Sini Sunny, Andrew J. Paterson, Namakkal‐Soorappan Rajasekaran, Jarrod W. Barnes, Jianhua Zhang, Hind Lal, Min Xie, Victor M. Darley‐Usmar, John C. Chatham, Adam R. Wende
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 19 (2023)
Background Lifestyle and metabolic diseases influence the severity and pathogenesis of cardiovascular disease through numerous mechanisms, including regulation via posttranslational modifications. A specific posttranslational modification, the additi
Externí odkaz:
https://doaj.org/article/be156b0fab8e4ad2aa747f5829ccfd51
Autor:
Muralidharan Thoddi Ramamurthy, Vinod Kumar Balakrishnan, Sini Sunny, Abinayaa Rajkumar, Sandhya Sundaram, Preetam Krishnamurthy, Nagendra Boopathy Senguttuvan, Arunan Murali, J. D. Roy Santhosham, Kalaiselvi Periandavan, Namakkal S. Rajasekaran
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2023)
The reported incidence of liposarcomas in ~2,000 cases annually results in about 30% of myxoid liposarcomas. Cardiac myoxid liposarcomas are very rare; their presentation could be cardiac tamponade, due to direct compression of the tumor and/or peric
Externí odkaz:
https://doaj.org/article/6121db0e37b24258ab10dcf4886aa0cb
Autor:
Justin M. Quiles, Mark E. Pepin, Sini Sunny, Sandeep B. Shelar, Anil K. Challa, Brian Dalley, John R. Hoidal, Steven M. Pogwizd, Adam R. Wende, Namakkal S. Rajasekaran
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Although recent advances in the treatment of acute coronary heart disease have reduced mortality rates, few therapeutic strategies exist to mitigate the progressive loss of cardiac function that manifests as heart failure. Nuclear factor, er
Externí odkaz:
https://doaj.org/article/0bacb871034845faa009f27435e581fe
Autor:
Sini Sunny, Arun Jyothidasan, Cynthia L. David, Krishna Parsawar, Arul Veerappan, Dean P. Jones, Steven Pogwizd, Namakkal S. Rajasekaran
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Nuclear factor erythroid 2-related factor 2 (NRF2), a redox sensor, is vital for cellular redox homeostasis. We reported that transgenic mice expressing constitutively active Nrf2 (CaNrf2-TG) exhibit reductive stress (RS). In this study, we identifie
Externí odkaz:
https://doaj.org/article/6f46c3b363dc403288078fd580f7ae56
Autor:
Rajkumar, Abinayaa, Shankar, Dhamodharan, Panchalingam, Gokulprasanth, Jayakumar, Deepthy, sini sunny, PERIANDAVAN, K.A.L.A.I.S.E.L.V.I.
Publikováno v:
In Free Radical Biology and Medicine 1 November 2024 224 Supplement 1:S72-S73
Autor:
Sini Sunny, Namakkal S. Rajasekaran, Justin M. Quiles, Adam R. Wende, Sandeep B. Shelar, Steven M. Pogwizd, John R. Hoidal, Brian Dalley, Mark E Pepin, Anil K. Challa
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports
Although recent advances in the treatment of acute coronary heart disease have reduced mortality rates, few therapeutic strategies exist to mitigate the progressive loss of cardiac function that manifests as heart failure. Nuclear factor, erythroid 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf2a800252cdf9a1b96daebc480b9d68
https://doaj.org/article/0bacb871034845faa009f27435e581fe
https://doaj.org/article/0bacb871034845faa009f27435e581fe
Autor:
Sini Sunny, Cynthia L David, Krishna Parsawar, Steven pogwizd, Rajasekaran N Namakkal-Soorappan
Publikováno v:
Circulation Research. 131
Background: A real-time action of Nrf2 in response to a stress is vital to preserve the redox homeostasis, but its activation under unstressed settings tilt the redox balance towards the reductive arm, leading to reductive stress (RS). In this study,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d22200e847ae3dcfb2cfefc00cf5ab90
https://doi.org/10.1161/res.131.suppl_1.p2045
https://doi.org/10.1161/res.131.suppl_1.p2045
Publikováno v:
Circulation Research. 131
Background: Causal mechanisms and specific consequences of heart failure (HF) with preserved ejection fraction (HFpEF) are unknown. We compared the EF of ST-elevation myocardial infarction (STEMI) patients with the regional wall motion abnormalities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f73ef68e38513498a4903e52905d6ea0
https://doi.org/10.1161/res.131.suppl_1.p3025
https://doi.org/10.1161/res.131.suppl_1.p3025