Dual α-globin-truncated erythropoietin receptor knockin restores hemoglobin production in α-thalassemia-derived erythroid cells

Autor: Chu, Simon N. ^{1, 2, 3}, Soupene, Eric ⁴, Sharma, Devesh ^{1, 2}, Sinha, Roshani ^{1, 2}, McCreary, Travis ^{1, 2}, Hernandez, Britney ⁵, Shen, Huifeng ⁵, Wienert, Beeke ⁶, Bowman, Chance ^{1, 2, 7}, Yin, Han ^{1, 3}, Lesch, Benjamin J. ^{1, 2, 7}, Jia, Kun ^{1, 2}, Romero, Kathleen A. ⁵, Kostamo, Zachary ⁵, Zhang, Yankai ⁵, Tran, Tammy ^{1, 2}, Cordero, Marco ^{1, 2}, Homma, Shota ⁸, Hampton, Jessica P. ⁹, Gardner, James M. ^{1, 3}, Conklin, Bruce R. ^{6, 10}, MacKenzie, Tippi C. ^{1, 2}, Sheehan, Vivien A. ⁵, Porteus, Matthew H. ⁹, Cromer, M. Kyle ^{1, 2, 7, 11, ∗}

Publikováno v: In Cell Reports 28 January 2025 44(1)

Epigenetic Profiling of PTPN11 Mutant JMML Hematopoietic Stem and Progenitor Cells Reveals an Aberrant Histone Landscape.

Autor: Sinha, Roshani¹ (AUTHOR) roshani@stanford.edu, Dvorak, Mai² (AUTHOR) maidvora@stanford.edu, Ganesan, Ananthakrishnan² (AUTHOR) ananthg@stanford.edu, Kalesinskas, Larry² (AUTHOR) lkalesin@stanford.edu, Niemeyer, Charlotte M.³ (AUTHOR) charlotte.niemeyer@uniklinik-freiburg.de, Flotho, Christian³ (AUTHOR) christian.flotho@uniklinik-freiburg.de, Sakamoto, Kathleen M.⁴ (AUTHOR) kmsakamo@stanford.edu, Lacayo, Norman⁴ (AUTHOR) lacayon@stanford.edu, Patil, Rachana Vinay¹ (AUTHOR) rpatil1@stanford.edu, Perriman, Rhonda¹ (AUTHOR) rhondap@stanford.edu, Cepika, Alma-Martina¹ (AUTHOR) acepika@stanford.edu, Liu, Yunying Lucy¹ (AUTHOR) ylliu19@stanford.edu, Kuo, Alex² (AUTHOR) alexjkuo0229@gmail.com, Utz, Paul J.² (AUTHOR) pjutz@stanford.edu, Khatri, Purvesh² (AUTHOR) pkhatri@stanford.edu, Bertaina, Alice^1,4 (AUTHOR) aliceb1@stanford.edu

Publikováno v: Cancers. Nov2023, Vol. 15 Issue 21, p5204. 16p.

301 - G-CSF +/- Plerixafor PBSC Mobilization and αβ t-Cell/CD19 B-Cell Depletion Impact Donor T-Cell Gene Expression Profiles

Autor: Montiel-Esparza, Raul, Sinha, Roshani, Barbarito, Giulia, Patil, Rachana, Saini, Gopin, Shyr, David C., Davies, Kimberly, Ji, Xuhuai, Yao, Zhenyu, Parkman, Robertson, Bertaina, Alice

Publikováno v: In Transplantation and Cellular Therapy February 2023 29(2) Supplement:S230-S231

Novel Humanized Loss-of-Function NF1 Mouse Model of Juvenile Myelomonocytic Leukemia

Autor: Sinha, Roshani ^*, Patil, Rachana ^*, Romano, Rosa ^*, Lee, Esmond ^*, Yao, Zhenyu ^*, Liu, Y. Lucy, Porteus, Matthew H., Bertaina, Alice

Publikováno v: In Blood 15 November 2022 140 Supplement 1:9765-9766

454 - Kinetics of Gamma Delta T-Cell Immune Reconstitution: An Immunophenotypic and Molecular Analysis

Autor: Barbarito, Giulia, Louis, David M, Saini, Gopin, Ji, Xuhuai, Kristovich, Karen, Sinha, Roshani, Patil, Rachana, Batish, Arpit, Parkman, Robertson, Bertaina, Alice

Publikováno v: In Transplantation and Cellular Therapy March 2022 28(3) Supplement:S355-S356