Clinical relevance and therapeutic predictive ability of hypoxia biomarkers in head and neck cancer tumour models.

Autor: Lee TW; Auckland Cancer Society Research Centre, University of Auckland, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, New Zealand., Singleton DC; Auckland Cancer Society Research Centre, University of Auckland, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, New Zealand.; Department of Molecular Medicine and Pathology, University of Auckland, New Zealand., Harms JK; Auckland Cancer Society Research Centre, University of Auckland, New Zealand., Lu M; Auckland Cancer Society Research Centre, University of Auckland, New Zealand., McManaway SP; Auckland Cancer Society Research Centre, University of Auckland, New Zealand., Lai A; Auckland Cancer Society Research Centre, University of Auckland, New Zealand.; Department of Pharmacology and Clinical Pharmacology, University of Auckland, New Zealand., Tercel M; Auckland Cancer Society Research Centre, University of Auckland, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, New Zealand., Pruijn FB; Auckland Cancer Society Research Centre, University of Auckland, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, New Zealand., Macann AMJ; Department of Radiation Oncology, Auckland City Hospital, New Zealand., Hunter FW; Auckland Cancer Society Research Centre, University of Auckland, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, New Zealand.; Oncology Therapeutic Area, Janssen Research and Development, Spring House, PA, USA., Wilson WR; Auckland Cancer Society Research Centre, University of Auckland, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, New Zealand., Jamieson SMF; Auckland Cancer Society Research Centre, University of Auckland, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, New Zealand.; Department of Pharmacology and Clinical Pharmacology, University of Auckland, New Zealand.

Publikováno v: Molecular oncology [Mol Oncol] 2024 Aug; Vol. 18 (8), pp. 1885-1903. Date of Electronic Publication: 2024 Mar 01.

In vitro breast cancer models for studying mechanisms of resistance to endocrine therapy.

Autor: Cheng GJ; Auckland Cancer Society Research Centre, Faculty of Medical and Health Sciences, The University of Auckland, Auckland 1023, New Zealand., Leung EY; Auckland Cancer Society Research Centre, Faculty of Medical and Health Sciences, The University of Auckland, Auckland 1023, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, The University of Auckland, Auckland 1023, New Zealand.; Department of Molecular Medicine and Pathology, The University of Auckland, Auckland 1023, New Zealand., Singleton DC; Auckland Cancer Society Research Centre, Faculty of Medical and Health Sciences, The University of Auckland, Auckland 1023, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, The University of Auckland, Auckland 1023, New Zealand.; Department of Molecular Medicine and Pathology, The University of Auckland, Auckland 1023, New Zealand.

Publikováno v: Exploration of targeted anti-tumor therapy [Explor Target Antitumor Ther] 2022; Vol. 3 (3), pp. 297-320. Date of Electronic Publication: 2022 Jun 01.

Patient-Derived Xenograft and Organoid Models for Precision Medicine Targeting of the Tumour Microenvironment in Head and Neck Cancer.

Autor: Lee TW; Auckland Cancer Society Research Centre, University of Auckland, Auckland 1023, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Auckland 1010, New Zealand., Lai A; Auckland Cancer Society Research Centre, University of Auckland, Auckland 1023, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Auckland 1010, New Zealand.; Department of Pharmacology and Clinical Pharmacology, University of Auckland, Auckland 1023, New Zealand., Harms JK; Auckland Cancer Society Research Centre, University of Auckland, Auckland 1023, New Zealand., Singleton DC; Auckland Cancer Society Research Centre, University of Auckland, Auckland 1023, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Auckland 1010, New Zealand., Dickson BD; Auckland Cancer Society Research Centre, University of Auckland, Auckland 1023, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Auckland 1010, New Zealand., Macann AMJ; Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Auckland 1010, New Zealand.; Department of Radiation Oncology, Auckland City Hospital, Auckland 1023, New Zealand., Hay MP; Auckland Cancer Society Research Centre, University of Auckland, Auckland 1023, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Auckland 1010, New Zealand., Jamieson SMF; Auckland Cancer Society Research Centre, University of Auckland, Auckland 1023, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Auckland 1010, New Zealand.; Department of Pharmacology and Clinical Pharmacology, University of Auckland, Auckland 1023, New Zealand.

Publikováno v: Cancers [Cancers (Basel)] 2020 Dec 12; Vol. 12 (12). Date of Electronic Publication: 2020 Dec 12.

N-Methyl-D-Aspartate Receptor Hypofunction in Meg-01 Cells Reveals a Role for Intracellular Calcium Homeostasis in Balancing Megakaryocytic-Erythroid Differentiation.

Autor: Hearn JI; Department of Molecular Medicine and Pathology, School of Medical Sciences, University of Auckland, Auckland, New Zealand., Green TN; Department of Molecular Medicine and Pathology, School of Medical Sciences, University of Auckland, Auckland, New Zealand., Chopra M; Department of Molecular Medicine and Pathology, School of Medical Sciences, University of Auckland, Auckland, New Zealand., Nursalim YNS; Department of Molecular Medicine and Pathology, School of Medical Sciences, University of Auckland, Auckland, New Zealand., Ladvanszky L; Department of Molecular Medicine and Pathology, School of Medical Sciences, University of Auckland, Auckland, New Zealand., Knowlton N; Department of Molecular Medicine and Pathology, School of Medical Sciences, University of Auckland, Auckland, New Zealand., Blenkiron C; Department of Molecular Medicine and Pathology, School of Medical Sciences, University of Auckland, Auckland, New Zealand., Poulsen RC; Department of Medicine, School of Medicine, University of Auckland, Auckland, New Zealand.; Department of Pharmacology and Clinical Pharmacology, School of Medical Sciences, University of Auckland, Auckland, New Zealand., Singleton DC; Auckland Cancer Society Research Centre, University of Auckland, Auckland, New Zealand., Bohlander SK; Department of Molecular Medicine and Pathology, School of Medical Sciences, University of Auckland, Auckland, New Zealand., Kalev-Zylinska ML; Department of Molecular Medicine and Pathology, School of Medical Sciences, University of Auckland, Auckland, New Zealand.; LabPlus Haematology, Auckland City Hospital, Auckland, New Zealand.

Publikováno v: Thrombosis and haemostasis [Thromb Haemost] 2020 Apr; Vol. 120 (4), pp. 671-686. Date of Electronic Publication: 2020 Apr 14.

Derivation of Breast Cancer Cell Lines Under Physiological (5%) Oxygen Concentrations.

Autor: Leung EY; Auckland Cancer Society Research Centre, University of Auckland, Auckland, New Zealand.; Department of Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand., Askarian-Amiri ME; Auckland Cancer Society Research Centre, University of Auckland, Auckland, New Zealand.; Department of Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand., Singleton DC; Auckland Cancer Society Research Centre, University of Auckland, Auckland, New Zealand., Ferraro-Peyret C; Univ Lyon, Claude Bernard University, Cancer Research Center of Lyon, INSERM 1052, CNRS5286, Faculty of Pharmacy, Lyon, France.; Hospices Civils de Lyon, Molecular Biology of Tumors, GHE Hospital, Bron, France., Joseph WR; Auckland Cancer Society Research Centre, University of Auckland, Auckland, New Zealand., Finlay GJ; Auckland Cancer Society Research Centre, University of Auckland, Auckland, New Zealand.; Department of Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand., Broom RJ; Auckland City Hospital-Oncology, Grafton, Auckland, New Zealand., Kakadia PM; Department of Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand., Bohlander SK; Department of Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand., Marshall E; Auckland Cancer Society Research Centre, University of Auckland, Auckland, New Zealand., Baguley BC; Auckland Cancer Society Research Centre, University of Auckland, Auckland, New Zealand.

Publikováno v: Frontiers in oncology [Front Oncol] 2018 Oct 12; Vol. 8, pp. 425. Date of Electronic Publication: 2018 Oct 12 (Print Publication: 2018).