Zobrazeno 1 - 10
of 385
pro vyhledávání: '"Single-cell data"'
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-28 (2024)
Abstract In the past two decades, genomics has advanced significantly, with single-cell RNA-sequencing (scRNA-seq) marking a pivotal milestone. ScRNA-seq provides unparalleled insights into cellular diversity and has spurred diverse studies across mu
Externí odkaz:
https://doaj.org/article/e5ac32a1a40a433182d8431c577780c9
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Externí odkaz:
https://doaj.org/article/1fec7feb3992400e9b4915589d2ec78e
Publikováno v:
Molecular Systems Biology, Vol 20, Iss 7, Pp 744-766 (2024)
Abstract The advent of high-throughput single-cell genomics technologies has fundamentally transformed biological sciences. Currently, millions of cells from complex biological tissues can be phenotypically profiled across multiple modalities. The sc
Externí odkaz:
https://doaj.org/article/b35a19cc1d0843248f71d65ab92b1c1e
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundIncreasing evidence reveals the involvement of mitochondria and macrophage polarisation in tumourigenesis and progression. This study aimed to establish mitochondria and macrophage polarisation-associated molecular signatures to predict pro
Externí odkaz:
https://doaj.org/article/59a2a4affcc346a8bbc12b64b8f889c5
Publikováno v:
Frontiers in Bioinformatics, Vol 4 (2024)
Rapid advancements in high-throughput single-cell RNA-seq (scRNA-seq) technologies and experimental protocols have led to the generation of vast amounts of transcriptomic data that populates several online databases and repositories. Here, we systema
Externí odkaz:
https://doaj.org/article/43bc2c481c3141f5864cbec92ea63a55
Publikováno v:
Advanced Science, Vol 11, Iss 19, Pp n/a-n/a (2024)
Abstract Transformer‐based models have revolutionized single cell RNA‐seq (scRNA‐seq) data analysis. However, their applicability is challenged by the complexity and scale of single‐cell multi‐omics data. Here a novel single‐cell multi‐
Externí odkaz:
https://doaj.org/article/e2620a0fd7d44279b262c18e6dabd205
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Background Skin cutaneous melanoma (SKCM) is a highly lethal cancer, ranking among the top four deadliest cancers. This underscores the urgent need for novel biomarkers for SKCM diagnosis and prognosis. Anoikis plays a vital role in cancer g
Externí odkaz:
https://doaj.org/article/75b949bae576474db55891b755fbf578
Publikováno v:
Journal of Analytical Science and Technology, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract Single-cell multi-omics technology has catalyzed a transformative shift in contemporary cell biology, illuminating the nuanced relationship between genotype and phenotype. This paradigm shift hinges on the understanding that while genomic st
Externí odkaz:
https://doaj.org/article/ba045fec1ea04f2ab25cf8acdcfdebe8
Publikováno v:
Biomolecules, Vol 14, Iss 11, p 1396 (2024)
In the past decade, inferring developmental trajectories from single-cell data has become a significant challenge in bioinformatics. RNA velocity, with its incorporation of directional dynamics, has significantly advanced the study of single-cell tra
Externí odkaz:
https://doaj.org/article/2494018b86c548bd8c7629520bf5ff6e
Autor:
Stian Tornaas, Dimitrios Kleftogiannis, Siren Fromreide, Hilde Ytre-Hauge Smeland, Hans Jørgen Aarstad, Olav Karsten Vintermyr, Lars Andreas Akslen, Daniela Elena Costea, Harsh Nitin Dongre
Publikováno v:
Heliyon, Vol 10, Iss 10, Pp e31191- (2024)
To decipher the interactions between various components of the tumor microenvironment (TME) and tumor cells in a preserved spatial context, a multiparametric approach is essential. In this pursuit, imaging mass cytometry (IMC) emerges as a valuable t
Externí odkaz:
https://doaj.org/article/6344f46aeae6447b80fe879f9f1b0eb1