Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Single-cell atlas"'
Autor:
Lu Pan, Paolo Parini, Roman Tremmel, Joseph Loscalzo, Volker M. Lauschke, Bradley A. Maron, Paola Paci, Ingemar Ernberg, Nguan Soon Tan, Zehuan Liao, Weiyao Yin, Sundararaman Rengarajan, Xuexin Li, The SCA Consortium
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-21 (2024)
Abstract Single-cell sequencing datasets are key in biology and medicine for unraveling insights into heterogeneous cell populations with unprecedented resolution. Here, we construct a single-cell multi-omics map of human tissues through in-depth cha
Externí odkaz:
https://doaj.org/article/bfac2c6a06f6422a8ceb3444a8f601fb
Autor:
Teresa Attenborough, Kate A Rawlinson, Carmen L Diaz Soria, Kirsty Ambridge, Geetha Sankaranarayanan, Jennie Graham, James A Cotton, Stephen R Doyle, Gabriel Rinaldi, Matthew Berriman
Publikováno v:
eLife, Vol 13 (2024)
Schistosoma mansoni is a parasitic flatworm that causes the major neglected tropical disease schistosomiasis. The miracidium is the first larval stage of the life cycle. It swims and infects a freshwater snail, transforms into a mother sporocyst, whe
Externí odkaz:
https://doaj.org/article/492c0842a7244a4089c106d100e3d525
Autor:
Ricardo Omar Ramirez Flores, Jan David Lanzer, Daniel Dimitrov, Britta Velten, Julio Saez-Rodriguez
Publikováno v:
eLife, Vol 12 (2023)
Biomedical single-cell atlases describe disease at the cellular level. However, analysis of this data commonly focuses on cell-type-centric pairwise cross-condition comparisons, disregarding the multicellular nature of disease processes. Here, we pro
Externí odkaz:
https://doaj.org/article/93be7c3e8a9646d7971c6c8d0c8f4c51
Autor:
Fanjie Wu, Chenghao Lin, Yutong Han, Dingli Zhou, Kang Chen, Minglei Yang, Qinyuan Xiao, Haiyue Zhang, Weizhong Li
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 5583-5600 (2023)
In the post COVID-19 era, new SARS-CoV-2 variant strains may continue emerging and long COVID is poised to be another public health challenge. Deciphering the molecular susceptibility of receptors to SARS-CoV-2 spike protein is critical for understan
Externí odkaz:
https://doaj.org/article/6442e949fd9b4eb7b61e9235404ae9a6
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionAgeing in the human bone marrow is associated with immune function decline that results in the elderly being vulnerable to illnesses. A comprehensive healthy bone marrow consensus atlas can serve as a reference to study the immunological
Externí odkaz:
https://doaj.org/article/db86f160d5054a11bf98767c888c519f
Autor:
Chengyan Zhang, Zeyu Ma, Xi Nan, Wenhui Wang, Xianchang Zeng, Jinming Chen, Zhijian Cai, Jianli Wang
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundCoronavirus disease 2019 (COVID-19) and inflammatory bowel disease (IBD) are both caused by a disordered immune response and have direct and profound impacts on health care services. In this study, we implemented transcriptomic and single-c
Externí odkaz:
https://doaj.org/article/5f5593374d404b359251ce9ce20521ef
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Akademický článek
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Akademický článek
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Autor:
Alexander J Tarashansky, Jacob M Musser, Margarita Khariton, Pengyang Li, Detlev Arendt, Stephen R Quake, Bo Wang
Publikováno v:
eLife, Vol 10 (2021)
Comparing single-cell transcriptomic atlases from diverse organisms can elucidate the origins of cellular diversity and assist the annotation of new cell atlases. Yet, comparison between distant relatives is hindered by complex gene histories and div
Externí odkaz:
https://doaj.org/article/e61b8c6e924b4228a38a43ea366b4ea4