Zobrazeno 1 - 10
of 211
pro vyhledávání: '"Single-cell RNA sequence"'
Autor:
Akira Saito, Toshiyuki Koya, Ami Aoki, Shun Naramoto, Hiroshi Ueno, Yuki Nishiyama, Kenjiro Shima, Yosuke Kimura, Takashi Hasegawa, Satoshi Watanabe, Yasuyoshi Ohshima, Keisuke Suzuki, Katsuyo Ohashi-Doi, Toshiaki Kikuchi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Sublingual immunotherapy (SLIT) has received considerable attention as a method for allergen immunotherapy (AIT). However, the mechanism of SLIT, especially its timing, has not been thoroughly investigated. We evaluated therapeutic and proph
Externí odkaz:
https://doaj.org/article/fd44cc5a7c2948bdbfcbaa10a6749b99
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Colorectal cancer is one of the most common cancers around the world, which is a severe threat to people’s health. SMAD4 belongs to the dwarfin/SMAD family, which plays a crucial role in TGF-β and BMP signal pathways. As the molecular cha
Externí odkaz:
https://doaj.org/article/b03ecd5bbd0b4e9d9fbc6e737bd6142b
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionKinesin family member 20A (KIF20A) is essential for cell proliferation and is implicated in promoting tumor progression, but its role in hepatocellular carcinoma (HCC) remains poorly studied.MethodsThrough the analysis of bulk RNA-sequenc
Externí odkaz:
https://doaj.org/article/af99f36bd85846b8820624899ad46fcf
Autor:
Pei-Lin Li, Da-Fu Chen, Xiao-Tong Li, Rui-Cong Hao, Zhi-Dong Zhao, Zhi-Ling Li, Bo-Feng Yin, Jie Tang, Yu-Wen Luo, Chu-Tse Wu, Jing-Jun Nie, Heng Zhu
Publikováno v:
Bioactive Materials, Vol 34, Iss , Pp 204-220 (2024)
Skeletal stem cells (SSC) have gained attentions as candidates for the treatment of osteoarthritis due to their osteochondrogenic capacity. However, the immunomodulatory properties of SSC, especially under delivery operations, have been largely ignor
Externí odkaz:
https://doaj.org/article/93e7148b9e5047eca8e330ca5c368181
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Numerous methods for bulk RNA sequence deconvolution have been developed to identify cellular targets of diseases by understanding the composition of cell types in disease-related tissues. However, issues of heterogeneity in gene expression
Externí odkaz:
https://doaj.org/article/b3b30ee9f2434677b5d0756e7d832501
Autor:
Shigeru Tanaka, Takuya Yamamoto, Arifumi Iwata, Masahiro Kiuchi, Kota Kokubo, Tomohisa Iinuma, Takahiro Sugiyama, Toyoyuki Hanazawa, Kiyoshi Hirahara, Kei Ikeda, Hiroshi Nakajima
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-8 (2024)
Abstract Objectives IgG4-related disease (IgG4-RD) is a systemic autoimmune disease with an unknown etiology, affecting single/multiple organ(s). Pathological findings include the infiltration of IgG4-producing plasma cells, obliterative phlebitis, a
Externí odkaz:
https://doaj.org/article/1cbc3a625e2247858a84bf39dddf5639
Publikováno v:
Heliyon, Vol 10, Iss 14, Pp e34295- (2024)
Metabolic syndrome(MS) is a separate risk factor for the advancement of atherosclerosis(AS) plaque but mechanism behind this remains unclear. There may be a significant role for the immune system in this process. This study aims to identify potential
Externí odkaz:
https://doaj.org/article/3aee6aa9bdd44b9195ad8bc0c2606d09
Publikováno v:
Biomedicines, Vol 12, Iss 9, p 2157 (2024)
Background: Androgen deprivation therapy (ADT) is the mainstay of treatment for prostate cancer, yet dynamic molecular changes from hormone-sensitive to castration-resistant states in patients treated with ADT remain unclear. Methods: In this study,
Externí odkaz:
https://doaj.org/article/88fbc4235c184d89a59aade76f73827d
Autor:
Mojtaba Shekarkar Azgomi, Giusto Davide Badami, Miriam Di Caro, Bartolo Tamburini, Miriana Fallo, Costanza Dieli, Kiana Ebrahimi, Francesco Dieli, Marco Pio La Manna, Nadia Caccamo
Publikováno v:
Cells, Vol 13, Iss 18, p 1529 (2024)
Tuberculosis (TB) remains one of the leading causes of death among infectious diseases, with 10.6 million new cases and 1.3 million deaths reported in 2022, according to the most recent WHO report. Early studies have shown an expansion of γδ T cell
Externí odkaz:
https://doaj.org/article/63c283960f9b41b6a53830faddecfba3
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundHyaluronan-mediated motility receptor (HMMR) is overexpressed in multiple carcinomas and influences the development and treatment of several cancers. However, its role in hepatocellular carcinoma (HCC) remains unclear.MethodsThe “limma”
Externí odkaz:
https://doaj.org/article/54d5b9f63d0c4e6ba53d70a6b396a4e5