Zobrazeno 1 - 10
of 1 638
pro vyhledávání: '"Single oral dose"'
Autor:
Jayesh V. Beladiya, Anita A. Mehta
Publikováno v:
Laboratory Animal Research, Vol 37, Iss 1, Pp 1-10 (2021)
Abstract Background The aim of study was to evaluate the single oral dose and 28 day repeated oral administration toxicity profile of the synthetic compound Gαq-RGS2 signaling inhibitor, (1-(5-chloro-2-hydroxyphenyl)-3-(4-(trifluoromethyl)phenyl)-1
Externí odkaz:
https://doaj.org/article/408d5f94658e4b288699e857930e9801
Autor:
Johannes Streffer, Valerie Treyer, Alfred Buck, Simon M. Ametamey, Milen Blagoev, Ralph P Maguire, Aurélie Gautier, Yves P. Auberson, Mark E. Schmidt, Ivan-Toma Vranesic, Baltazar Gomez-Mancilla, Fabrizio Gasparini
Publikováno v:
NeuroImage, Vol 230, Iss , Pp 117785- (2021)
Mavoglurant binds to same allosteric site on metabotropic glutamate receptor 5 (mGluR5) as [11C]-ABP688, a radioligand. This open-label, single-center pilot study estimates extent of occupancy of mGluR5 receptors following single oral doses of mavogl
Externí odkaz:
https://doaj.org/article/ade72d8efd5c49d88ff715c43ad5a8a3
Autor:
Dong-Gu Kim, Jeonghoon Lee, Wonnam Kim, Hyo-Jin An, Jong-Hyun Lee, Jaeki Chang, Sa-Haeng Kang, Young-Jae Song, Yong-Deok Jeon, Jong-Sik Jin
Publikováno v:
Plants, Vol 10, Iss 6, p 1126 (2021)
The Glycyrrhiza radix (Licorice) is one of the most commonly used medicinal plants in Asian countries, such as China, India, and Korea. It has been traditionally used to treat many diseases, including cough, cold, asthma, fatigue, gastritis, and resp
Externí odkaz:
https://doaj.org/article/939d6846b44747818f52a42909677fd5
Autor:
Olivia Carlile, Douglas R. Mader, Lara K. Maxwell, Courtney D O'Connor, Kaylin J Caperton, Bette Zirkelbach, Nicole I. Stacy, Elliott R. Jacobson, Richie Moretti
Publikováno v:
The Veterinary Quarterly
article-version (VoR) Version of Record
Veterinary Quarterly, Vol 41, Iss 1, Pp 323-331 (2021)
article-version (VoR) Version of Record
Veterinary Quarterly, Vol 41, Iss 1, Pp 323-331 (2021)
Background: The coccidian protozoan, Caryospora cheloniae, has been associated with severe enteritis and encephalitis in immature farm-raised green turtles (Chelonia mydas) in the Cayman Islands, immature green turtles off the coast of Florida, and i
Publikováno v:
Journal of the American Veterinary Medical Association. :1-7
OBJECTIVE To investigate the effects of a single oral dose of gabapentin on fear-based aggressive behaviors (FABs) in cats during veterinary examinations. ANIMALS 55 healthy pet cats (26 with and 29 without a history of FAB during veterinary visits [
Publikováno v:
Journal of Veterinary Pharmacology and Therapeutics. 45:63-68
This study aimed to investigate pharmacokinetics of fluoxetine in horses and validate a method for liquid chromatography mass spectrometry analysis of serum levels. Fluoxetine pharmacokinetics were determined using 10 healthy, adult horses. Fluoxetin
Autor:
Stanislav S. Rubakhin, Sookyoung Jeon, Matthew J. Kuchan, Jonathan V. Sweedler, Katherine M. Ranard, John W. Erdman, Qiyao Li
Publikováno v:
Nutrition Research. 93:79-86
Natural (RRR-) α-tocopherol (αT) is more bioactive than synthetic (all racemic, all rac-) αT, but not enough is known about the tissue kinetics of the 2 αT sources. We examined the time-course bioaccumulation of natural versus synthetic αT in ti
Autor:
Linda Gallegos, Luis A. Gomez-Puerta, Ana Vargas-Calla, Grupo de Trabajo en Cisticercosis en Perú, Armando E. Gonzalez, Gianfranco Arroyo, Hector H. Garcia, Juan Calcina, Teresa López, Javier A. Bustos, Robert H. Gilman
Publikováno v:
Revista Peruana de Medicina Experimental y Salud Pública. 38:296-301
The efficacy of two locally produced oxfendazole (OFZ) formulations against cysticercosis at 22,5% and 10%, versus a commercial formulation (Synanthic 9,06%) was evaluated in twenty-two naturally infected pigs that received a single oral dose of 30 m
Autor:
Fahad I. Al-Jenoobi, Mohammad Raish, Abdul Ahad, Mohd Aftab Alam, Abdullah M. Al-Mohizea, Ajaz Ahmad, Yousef A. Bin Jardan
Publikováno v:
Saudi Pharmaceutical Journal : SPJ
Saudi Pharmaceutical Journal, Vol 29, Iss 7, Pp 719-723 (2021)
Saudi Pharmaceutical Journal, Vol 29, Iss 7, Pp 719-723 (2021)
The aim of the present research was to describe the consequences of hyperlipidemia (HL) on the pharmacokinetics of glibenclamide (Gb) in poloxamer 407-induced hyperlipidemic rats. Rats were given intraperitoneal dose of poloxamer 407 to cause hyperli
Publikováno v:
Drug Design, Development and Therapy
Qian Zhang,1,2 Zhiqiang Wang,1â 3 Jingying Wu,1,2 Zhen Zhou,3 Renpeng Zhou,1,2 Wei Hu1,2 1Department of Clinical Pharmacology, The Second Hospital of Anhui Medical University, Hefei, Peopleâs Republic of China; 2Anhui Provincial Institute o