Zobrazeno 1 - 10
of 527
pro vyhledávání: '"Single nucleus RNA sequencing"'
Publikováno v:
BMC Neurology, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background The role of neurons in central post-stroke pain (CPSP) following thalamic hemorrhage remains unclear. This study aimed to identify key genes associated with post-thalamic hemorrhage pain and to explore their functions in neurons.
Externí odkaz:
https://doaj.org/article/a0983392699c4a439e23c2e62a2f0778
Autor:
Samet Agca, Aylin Domaniku‐Waraich, Sevval Nur Bilgic, Melis Sucuoglu, Meric Dag, Sukru Anil Dogan, Serkan Kir
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 5, Pp 1898-1914 (2024)
Abstract Background Tumour‐induced skeletal muscle wasting in the context of cancer cachexia is a condition with profound implications for patient survival. The loss of muscle mass is a significant clinical obstacle and is linked to reduced toleran
Externí odkaz:
https://doaj.org/article/d0200d5c1178411a990b0436bd6dd43a
Autor:
Quanlei Liu, Chunhao Shen, Yang Dai, Ting Tang, Changkai Hou, Hongyi Yang, Yihe Wang, Jinkun Xu, Yongchang Lu, Yunming Wang, Yongzhi Shan, Penghu Wei, Guoguang Zhao
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-19 (2024)
Abstract Background Temporal lobe epilepsy (TLE) is among the most common types of epilepsy and often leads to cognitive, emotional, and psychiatric issues due to the frequent seizures. A notable pathological change related to TLE is hippocampal scle
Externí odkaz:
https://doaj.org/article/f43d3a21a3bb48b8b83c1a93dcccf0d5
Autor:
Muhammad Ameen Jamal, Yixiao Cheng, Deling Jiao, Wen Cheng, Di Zou, Xia Wang, Taiyun Wei, Jianxiong Guo, Kaixiang Xu, Heng Zhao, Shaoxia Pu, Chang Yang, Yubo Qing, Baoyu Jia, Honghui Li, Rusong Zhao, Hong-Ye Zhao, Hong-Jiang Wei
Publikováno v:
Biological Research, Vol 57, Iss 1, Pp 1-18 (2024)
Abstract Background Infertility is a growing global health concern affecting millions of couples worldwide. Among several factors, an extreme body weight adversely affects reproductive functions. Leptin is a well-known adipokine that serves as an end
Externí odkaz:
https://doaj.org/article/568d092957b34cca8761e6cc29427490
Publikováno v:
Poultry Science, Vol 103, Iss 12, Pp 104259- (2024)
ABSTRACT: The black-bone chicken, known for its high melanin content, holds significant economic value due to this unique trait. Particularly notable is the prominent melanin deposition observed in its breast muscle. However, the molecular mechanisms
Externí odkaz:
https://doaj.org/article/d84aaea814144ddfb0aba61ed4ba3615
Autor:
Yanyan Zhu, Yin Zhang, Sheng He, Sanjun Yi, Hao Feng, Xianzhu Xia, Xiaodong Fang, Xiaoqian Gong, Pingsen Zhao
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-24 (2024)
Abstract Background Understanding the mechanism behind sepsis-associated encephalopathy (SAE) remains a formidable task. This study endeavors to shed light on the complex cellular and molecular alterations that occur in the brains of a mouse model wi
Externí odkaz:
https://doaj.org/article/906f618eb3e54b2f89ea9cd9aec73588
Autor:
Raghuveer Kavarthapu, Hong Lou, Thang Pham, Han Do, Mary E. Soliman, Taylor Badger, Ramya Balasubramanian, Victoria Huyhn, Maria De La Luz Sierra, Jacqueline C. Yano Maher, Veronica Gomez‐Lobo
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 10, Pp n/a-n/a (2024)
Abstract Background Classic galactosemia (CG) is an inborn error of galactose metabolism caused by mutations in the GALT gene. Premature ovarian insufficiency (POI) is a later complication that affects 80% of women with CG due to a significant declin
Externí odkaz:
https://doaj.org/article/09cb621325fa446889412815ff492563
Autor:
Seung Hyuk T. Lee, Kristina M. Garske, Uma Thanigai Arasu, Asha Kar, Zong Miao, Marcus Alvarez, Amogha Koka, Nicholas Darci-Maher, Jihane N. Benhammou, David Z. Pan, Tiit Örd, Dorota Kaminska, Ville Männistö, Sini Heinonen, Martin Wabitsch, Markku Laakso, Vatche G. Agopian, Joseph R. Pisegna, Kirsi H. Pietiläinen, Jussi Pihlajamäki, Minna U. Kaikkonen, Päivi Pajukanta
Publikováno v:
EBioMedicine, Vol 106, Iss , Pp 105232- (2024)
Summary: Background: Abdominal obesity increases the risk for non-alcoholic fatty liver disease (NAFLD), now known as metabolic dysfunction-associated steatotic liver disease (MASLD). Methods: To elucidate the directional cell-type level biological m
Externí odkaz:
https://doaj.org/article/a9ca2e74a8164304bf81b6dd03723f19
Autor:
Li, Peng *, †, 1, Wei, Xu *, †, 1, Zi, Qiongtao *, †, 1, Qu, Xiangyong *, †, He, Changqing *, †, Xiao, Bing ‡, Guo, Songchang *, †, 2
Publikováno v:
In Poultry Science December 2024 103(12)
Publikováno v:
Viruses, Vol 16, Iss 11, p 1779 (2024)
Dengue virus (DENV) infection causes various disease manifestations ranging from an asymptomatic state to severe, life-threatening dengue. Despite intensive research, the molecular mechanisms underlying the abnormal host responses and severe disease
Externí odkaz:
https://doaj.org/article/fa55a70b6145493ea8c9ec0abb0ac337