VSSP abrogates murine ovarian tumor-associated myeloid cell-driven immune suppression and induces M1 polarization in tumor-associated macrophages from ovarian cancer patients.

Autor: Khan ANH; Department of Internal Medicine, Roswell Park Comprehensive Cancer Center, Elm & Carlton Streets, Buffalo, NY, USA., Emmons TR; Department of Immunology, Roswell Park Comprehensive Cancer Center, Elm & Carlton Streets, Buffalo, NY, USA.; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Magner WJ; Department of Immunology, Roswell Park Comprehensive Cancer Center, Elm & Carlton Streets, Buffalo, NY, USA.; Department of Microbiology & Immunology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA., Alqassim E; Department of Cancer Prevention and Control, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.; Department of Pathology and Anatomical Sciences, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA., Singel KL; Department of Immunology, Roswell Park Comprehensive Cancer Center, Elm & Carlton Streets, Buffalo, NY, USA.; Office of Evaluation, Performance, and Reporting; Division of Program Coordination, Planning, and Strategic Initiatives; Office of the Director, National Institutes of Health, Bethesda, MD, USA., Ricciuti J; Department of Gynecologic Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA., Eng KH; Department of Biostatistics & Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA., Odunsi K; Department of Immunology, Roswell Park Comprehensive Cancer Center, Elm & Carlton Streets, Buffalo, NY, USA.; Department of Gynecologic Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.; University of Chicago Medicine Comprehensive Cancer Center, Chicago, IL, USA., Tomasi TB; Department of Immunology, Roswell Park Comprehensive Cancer Center, Elm & Carlton Streets, Buffalo, NY, USA.; Department of Microbiology & Immunology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA.; Department of Medicine, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA., Lee K; Department of Immunology, Roswell Park Comprehensive Cancer Center, Elm & Carlton Streets, Buffalo, NY, USA.; Department of Medicine, Roswell Park Comprehensive Cancer Center, University at Buffalo, Buffalo, NY, USA.; Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis, IN, USA., Abrams SI; Department of Immunology, Roswell Park Comprehensive Cancer Center, Elm & Carlton Streets, Buffalo, NY, USA., Mesa C; Center of Molecular Immunology, Havana, Cuba.; Innovative Immunotherapy Alliance, S. A. Mariel, Artemisa, Cuba., Segal BH; Department of Internal Medicine, Roswell Park Comprehensive Cancer Center, Elm & Carlton Streets, Buffalo, NY, USA. brahm.segal@roswellpark.org.; Department of Immunology, Roswell Park Comprehensive Cancer Center, Elm & Carlton Streets, Buffalo, NY, USA. brahm.segal@roswellpark.org.; Department of Medicine, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA. brahm.segal@roswellpark.org.

Publikováno v: Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2022 Oct; Vol. 71 (10), pp. 2355-2369. Date of Electronic Publication: 2022 Feb 15.

Mechanisms Driving Neutrophil-Induced T-cell Immunoparalysis in Ovarian Cancer.

Autor: Emmons TR; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, New York., Giridharan T; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, New York., Singel KL; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, New York., Khan ANH; Department of Internal Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, New York., Ricciuti J; Department of Gynecologic Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, New York., Howard K; Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts., Silva-Del Toro SL; Inflammation Program and Immunology Graduate Training Program, University of Iowa, Iowa City, Iowa., Debreceni IL; Inflammation Program and Immunology Graduate Training Program, University of Iowa, Iowa City, Iowa., Aarts CEM; Department of Blood Cell Research, Sanquin Research and Landsteiner Laboratory, Academic Medical Center (AMC), University of Amsterdam, Amsterdam, the Netherlands., Brouwer MC; Department of Immunopathology, Sanquin Research, Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands., Suzuki S; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, New York., Kuijpers TW; Department of Blood Cell Research, Sanquin Research and Landsteiner Laboratory, Academic Medical Center (AMC), University of Amsterdam, Amsterdam, the Netherlands.; Department of Pediatric Immunology, Rheumatology and Infectious Diseases, Emma Children's Hospital, Amsterdam UMC, Amsterdam, the Netherlands., Jongerius I; Department of Immunopathology, Sanquin Research, Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.; Department of Pediatric Immunology, Rheumatology and Infectious Diseases, Emma Children's Hospital, Amsterdam UMC, Amsterdam, the Netherlands., Allen LH; Inflammation Program, Departments of Medicine and Microbiology and Immunology, University of Iowa, Iowa City, Iowa., Ferreira VP; Department of Medical Microbiology and Immunology, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio., Schubart A; Novartis Institutes for BioMedical Research, Novartis Campus, Basel, Switzerland., Sellner H; Novartis Institutes for BioMedical Research, Novartis Campus, Basel, Switzerland., Eder J; Novartis Institutes for BioMedical Research, Novartis Campus, Basel, Switzerland., Holland SM; Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland., Ram S; Division of Infectious Diseases and Immunology, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts., Lederer JA; Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts., Eng KH; Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, New York., Moysich KB; Department of Cancer Prevention and Control, Roswell Park Comprehensive Cancer Center, Buffalo, New York., Odunsi K; Department of Gynecologic Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, New York.; Center for Immunotherapy, Roswell Park Comprehensive Cancer Center, Buffalo, New York., Yaffe MB; Center for Precision Cancer Medicine, Departments of Biological Engineering and Biology, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts.; Division of Acute Care Surgery, Trauma and Surgical Critical Care, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts., Zsiros E; Department of Gynecologic Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, New York.; Center for Immunotherapy, Roswell Park Comprehensive Cancer Center, Buffalo, New York., Segal BH; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, New York. brahm.segal@roswellpark.org.; Department of Internal Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, New York.; Department of Medicine, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York.

Publikováno v: Cancer immunology research [Cancer Immunol Res] 2021 Jul; Vol. 9 (7), pp. 790-810. Date of Electronic Publication: 2021 May 14.

ADULT PATIENTS WITH INBORN ERRORS OF IMMUNITY PRESENTING TO THE EMERGENCY DEPARTMENT.

Autor: Deetlefs, Mimi¹ maria.deetlefs@westerncape.gov.za, Kerbelker, Tamara², Hawarden, Di³

Publikováno v: Current Allergy & Clinical Immunology. Dec2024, Vol. 37 Issue 4, p192-196. 5p.

Quantification of Early-Stage Myeloid-Derived Suppressor Cells in Cancer Requires Excluding Basophils.

Autor: Khan ANH; Department of Internal Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, New York., Emmons TR; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, New York., Wong JT; Department of Pathology, Roswell Park Comprehensive Cancer Center, Buffalo, New York., Alqassim E; Department of Cancer Prevention and Control, Roswell Park Comprehensive Cancer Center, Buffalo, New York., Singel KL; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, New York., Mark J; Department of Gynecologic Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, New York., Smith BE; Department of Internal Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, New York., Tario JD; Department of Flow Cytometry, Roswell Park Comprehensive Cancer Center, Buffalo, New York., Eng KH; Department of Biostatistics & Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, New York., Moysich KB; Department of Cancer Prevention and Control, Roswell Park Comprehensive Cancer Center, Buffalo, New York., Odunsi K; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, New York.; Department of Gynecologic Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, New York., Abrams SI; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, New York., Segal BH; Department of Internal Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, New York. brahm.segal@roswellpark.org.; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, New York.; Department of Medicine, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York.

Publikováno v: Cancer immunology research [Cancer Immunol Res] 2020 Jun; Vol. 8 (6), pp. 819-828. Date of Electronic Publication: 2020 Apr 01.

Unlocking the Secrets of Extracellular Vesicles: Orchestrating Tumor Microenvironment Dynamics in Metastasis, Drug Resistance, and Immune Evasion.

Autor: Mir, Rashid¹ rashidmirtabuk@gmail.com, Baba, Sadaf Khursheed², Elfaki, Imadeldin³, Algehainy, Naseh¹, Alanazi, Mohammad A.¹, Altemani, Faisal H.¹, Tayeb, Faris Jamal¹, Barnawi, Jameel¹, Husain, Eram¹, Bedaiwi, Ruqaiah I.¹, Albalawi, Ibrahim Altedlawi⁴, Alhujaily, Muhanad⁵, Mir, Mohammad Muzaffar⁶, Almotairi, Reema¹, Alatwi, Hanan E.⁷, Albalawi, Aziz Dhaher⁸

Publikováno v: Journal of Cancer. 2024, Vol. 15 Issue 19, p6383-6415. 33p.