Oxathiaborolium: A Type of Chiral Lewis Acid Catalyst and Its Application in Catalytic and Highly Enantioselective Diels–Alder Reactions

Autor: Singam Naveen Kumar, Isaac Furay Yu, Rong-Jie Chein

Publikováno v: Organic Letters. 19:22-25

The first reported sulfur-stabilized borenium cations were synthesized through halide abstraction of a haloborane intermediate by halophilic reagents. Different from the well-known cationic oxazaborolidines, a sulfide instead of an amine was used to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6633e178947a53a24ed7c4724a0c793e
https://doi.org/10.1021/acs.orglett.6b03147

From Carbamate to Chalcone: Consecutive Anionic Fries Rearrangement, Anionic Si → C Alkyl Rearrangement, and Claisen-Schmidt Condensation

Autor: Rong-Jie Chein, Isaac Furay Yu, Suhas Ravindra Bavikar, Singam Naveen Kumar, Chebolu Naga Sesha Sai Pavan Kumar

Publikováno v: Organic letters. 20(17)

A highly efficient one-pot procedure was developed for the synthesis of various 2′-hydroxychalcones from phenyl diethylcarbamate, featuring consecutive Snieckus–Fries rearrangement, anionic Si → C alkyl rearrangement, and Claisen–Schmidt cond

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f61cc6b9404e59517df360728e41031e
https://pubmed.ncbi.nlm.nih.gov/30148638

Synthesis of new praziquantel analogues: Potential candidates for the treatment of schistosomiasis

Autor: Singam Naveen Kumar, Malapaka Chandrasekharam, Vaidya Jayathirtha Rao, Partha Sarathi Sadhu, Donato Cioli, Livia Pica-Mattoccia

Publikováno v: Bioorganic & medicinal chemistry letters
22 (2012): 1103–1106. doi:10.1016/j.bmcl.2011.11.108
info:cnr-pdr/source/autori:Partha Sarathi Sadhu a; Singam Naveen Kumar a; Malapaka Chandrasekharam b; Livia Pica-Mattoccia c; Donato Cioli c; Vaidya Jayathirtha Rao a/titolo:Synthesis of new Praziquantel analogues: Potential candidates for the treatment of schistosomiasis/doi:10.1016%2Fj.bmcl.2011.11.108/rivista:Bioorganic & medicinal chemistry letters (Print)/anno:2012/pagina_da:1103/pagina_a:1106/intervallo_pagine:1103–1106/volume:22

An efficient synthesis of antischistosomal drug praziquantel and analogues was achieved and the synthetic route designed was to afford structurally diverse analogues for better structure–activity relationship understanding. Total of nineteen PZQ an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4909e3bd8994cb2dfec42a998a2719d4
https://doi.org/10.1016/j.bmcl.2011.11.108