Zobrazeno 1 - 10
of 169
pro vyhledávání: '"Sing-Sing Way"'
Autor:
Petya Koleva, Jia He, Garett Dunsmore, Najmeh Bozorgmehr, Julia Lu, Maia Huynh, Stephanie Tollenaar, Vivian Huang, Jens Walter, Sing Sing Way, Shokrollah Elahi
Publikováno v:
Microbiome, Vol 12, Iss 1, Pp 1-23 (2024)
Abstract Background The establishment of microbial communities in neonatal mammals plays a pivotal role in shaping their immune responses to infections and other immune-related conditions. This process is influenced by a combination of endogenous and
Externí odkaz:
https://doaj.org/article/2ad7d12d3e5840baa8c2be949fc656ab
Autor:
Tzu-Yu Shao, Tony T. Jiang, Joseph Stevens, Abigail E. Russi, Ty D. Troutman, Anas Bernieh, Giang Pham, John J. Erickson, Emily M. Eshleman, Theresa Alenghat, Stephen C. Jameson, Kristin A. Hogquist, Casey T. Weaver, David B. Haslam, Hitesh Deshmukh, Sing Sing Way
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113323- (2023)
Summary: Intestinal colonization by antigenically foreign microbes necessitates expanded peripheral immune tolerance. Here we show commensal microbiota prime expansion of CD4 T cells unified by the Kruppel-like factor 2 (KLF2) transcriptional regulat
Externí odkaz:
https://doaj.org/article/44014ddf1b0d48c8b50adc38b432ca17
Autor:
Emily M. Eshleman, Tzu-Yu Shao, Vivienne Woo, Taylor Rice, Laura Engleman, Bailey J. Didriksen, Jordan Whitt, David B. Haslam, Sing Sing Way, Theresa Alenghat
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 4 (2023)
Aberrant immune responses to resident microbes promote inflammatory bowel disease and other chronic inflammatory conditions. However, how microbiota-specific immunity is controlled in mucosal tissues remains poorly understood. Here, we found that mic
Externí odkaz:
https://doaj.org/article/9020d0eccbb047c8940d96aee38825dc
Autor:
Ashley L. Severance, Jeremy M. Kinder, Lijun Xin, Ashley R. Burg, Tzu-Yu Shao, Giang Pham, Tamara Tilburgs, Wendy A. Goodman, Sam Mesiano, Sing Sing Way
Publikováno v:
iScience, Vol 25, Iss 6, Pp 104400- (2022)
Summary: Pregnancy stimulates an intricately coordinated assortment of physiological changes to accommodate growth of the developing fetus, while simultaneously averting rejection of genetically foreign fetal cells and tissues. Despite increasing evi
Externí odkaz:
https://doaj.org/article/7b95a0586b3243009339a6e36f9ae471
Autor:
Tzu-Yu Shao, Pallavi Kakade, Jessica N. Witchley, Corey Frazer, Kathryn L. Murray, Iuliana V. Ene, David B. Haslam, Thomas Hagan, Suzanne M. Noble, Richard J. Bennett, Sing Sing Way
Publikováno v:
Cell Reports, Vol 39, Iss 7, Pp 110837- (2022)
Summary: Systemic immunity is stringently regulated by commensal intestinal microbes, including the pathobiont Candida albicans. This fungus utilizes various transcriptional and morphological programs for host adaptation, but how this heterogeneity a
Externí odkaz:
https://doaj.org/article/9febbd1082cc40c5a74bef0cdea24015
Autor:
DeTomaso, Angela, Hyeyon Kim, Shauh, Jacqueline, Adulla, Anika, Zigo, Sarah, Ghoul, Maya, Presicce, Pietro, Kallapur, Suhas G., Goodman, Wendy, Tilburgs, Tamara, Sing-Sing Way, Hackney, David, Moore, John, Mesiano, Sam
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 6/18/2024, Vol. 121 Issue 25, p1-9, 15p
Autor:
Monica Cappelletti, Pietro Presicce, Ma Feiyang, Paranthaman Senthamaraikannan, Lisa A Miller, Matteo Pellegrini, Myung S Sim, Alan H Jobe, Senad Divanovic, Sing Sing Way, Claire A Chougnet, Suhas G Kallapur
Publikováno v:
PLoS Biology, Vol 19, Iss 9, p e3001385 (2021)
Intrauterine infection/inflammation (IUI) is a major contributor to preterm labor (PTL). However, IUI does not invariably cause PTL. We hypothesized that quantitative and qualitative differences in immune response exist in subjects with or without PT
Externí odkaz:
https://doaj.org/article/a2f9e4054a6a41a2b71f11a0c5742a24
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
In the fifteen minutes it takes to read this short commentary, more than 400 babies will have been born too early, another 300 expecting mothers will develop preeclampsia, and 75 unborn third trimester fetuses will have died in utero (stillbirth). Gi
Externí odkaz:
https://doaj.org/article/37f95c16e82546bab8e455e94be61238
Autor:
Nina Salinger Prasanphanich, Emily J. Gregory, John J. Erickson, Hilary Miller-Handley, Jeremy M. Kinder, Sing Sing Way
Publikováno v:
mBio, Vol 12, Iss 1 (2021)
Pregnancy makes women especially vulnerable to infection. The most common cause of bloodstream infection during pregnancy is by a bacterium called Escherichia coli
Externí odkaz:
https://doaj.org/article/cac28958ae194074969efe7f5f0919ac
Autor:
Nazanin Navabi, Jordan Whitt, Shu-en Wu, Vivienne Woo, Jessica Moncivaiz, Michael B. Jordan, Bruce A. Vallance, Sing Sing Way, Theresa Alenghat
Publikováno v:
Cell Reports, Vol 19, Iss 6, Pp 1165-1175 (2017)
Mucosal tissues are constantly in direct contact with diverse beneficial and pathogenic microbes, highlighting the need for orchestrating complex microbial signals to sustain effective host defense. Here, we show an essential role for intestinal epit
Externí odkaz:
https://doaj.org/article/cf9c6531f7a7493785cf44c32e72b6ad