Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Sing-Han Huang"'
Autor:
Chao-Di Chang, Min-Wu Chao, Hsueh-Yun Lee, Yi-Ting Liu, Huang-Ju Tu, Ssu-Ting Lien, Tony Eight Lin, Tzu-Ying Sung, Shih-Chung Yen, Sing-Han Huang, Kai-Cheng Hsu, Shiow-Lin Pan
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
AbstractInhibiting a specific target in cancer cells and reducing unwanted side effects has become a promising strategy in pancreatic cancer treatment. MAP4K4 is associated with pancreatic cancer development and correlates with poor clinical outcomes
Externí odkaz:
https://doaj.org/article/eeb87040e05f48b3ad27fb6a79897905
Autor:
Sing-Han Huang, Yi-Ting Chen, Xiang-Yu Lin, Yi-Yi Ly, Ssu-Ting Lien, Pei-Hsin Chen, Cheng-Tang Wang, Suh-Chin Wu, Chwen-Cheng Chen, Ching-Yung Lin
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The COVID-19 pandemic has had a widespread impact on a global scale, and the evolution of considerable dominants has already taken place. Some variants contained certain key mutations located on the receptor binding domain (RBD) of spike pro
Externí odkaz:
https://doaj.org/article/cb0c8d13813245d7a48bd64f32a5581e
Publikováno v:
BMC Bioinformatics, Vol 22, Iss S10, Pp 1-18 (2022)
Abstract Background The gene signatures have been considered as a promising early diagnosis and prognostic analysis to identify disease subtypes and to determine subsequent treatments. Tissue-specific gene signatures of a specific disease are an emer
Externí odkaz:
https://doaj.org/article/765db4176cea43ac8806f7b5d5a40d30
Autor:
Yi-Hsuan Chuang, Chun-Yu Lin, Jih-Chin Lee, Chia-Hwa Lee, Chia-Lin Liu, Sing-Han Huang, Jung-Yu Lee, Wen-Sen Lai, Jinn-Moon Yang
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13068 (2023)
Head and neck squamous cell carcinoma (HNSC) exhibits genetic heterogeneity in etiologies, tumor sites, and biological processes, which significantly impact therapeutic strategies and prognosis. While the influence of human papillomavirus on clinical
Externí odkaz:
https://doaj.org/article/c73c26dc207d4154878edf8d68860164
Autor:
Yi-Hsuan Chuang, Sing-Han Huang, Tzu-Mao Hung, Xiang-Yu Lin, Jung-Yu Lee, Wen-Sen Lai, Jinn-Moon Yang
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Many studies have proven the power of gene expression profile in cancer identification, however, the explosive growth of genomics data increasing needs of tools for cancer diagnosis and prognosis in high accuracy and short times. Here, we co
Externí odkaz:
https://doaj.org/article/3990bffa3c2042e49b32e117c0476788
Autor:
Chun-Yu Lin, Chia-Hwa Lee, Yi-Hsuan Chuang, Jung-Yu Lee, Yi-Yuan Chiu, Yan-Hwa Wu Lee, Yuh-Jyh Jong, Jenn-Kang Hwang, Sing-Han Huang, Li-Ching Chen, Chih-Hsiung Wu, Shih-Hsin Tu, Yuan-Soon Ho, Jinn-Moon Yang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Membrane proteins have been implicated in cancers, but studying the downstream effects of their perturbation remains challenging. Here, the authors map the membrane protein-regulated network of 15 cancers, a resource for prognostic biomarker developm
Externí odkaz:
https://doaj.org/article/34ff9a3b0c684e9db11e11f9aee3a016
Autor:
Yi-Hsuan Chuang, Chia-Hwa Lee, Chun-Yu Lin, Chia-Lin Liu, Sing-Han Huang, Jung-Yu Lee, Yi-Yuan Chiu, Jih-Chin Lee, Jinn-Moon Yang
Publikováno v:
Cancers, Vol 12, Iss 5, p 1324 (2020)
Although many studies have shown the association between smoking and the increased incidence and adverse prognosis of head and neck squamous cell carcinoma (HNSCC), the mechanisms and pharmaceutical targets involved remain unclear. Here, we integrate
Externí odkaz:
https://doaj.org/article/74b19b6a883b49e2836984977c90feba
Publikováno v:
PLoS ONE, Vol 10, Iss 1, p e0116347 (2015)
BACKGROUND:One of the crucial steps toward understanding the biological functions of a cellular system is to investigate protein-protein interaction (PPI) networks. As an increasing number of reliable PPIs become available, there is a growing need fo
Externí odkaz:
https://doaj.org/article/dd599ea96019424eab2f8bd23a5ec9d3
Autor:
Ying‐Wen Su, Wen‐Yu Huang, Huan‐Chau Lin, Po‐Nien Liao, Ching‐Yung Lin, Xiang‐Yu Lin, Sing‐Han Huang, Yi‐Ting Chen, Pao‐Shu Wu
Publikováno v:
Journal of Oral Pathology & Medicine. 52:245-254
Accumulating evidence shows that high expression of casein kinase 2 (CK2) and phosphorylated acetyl CoA carboxylase (pACC) in patients with squamous cell carcinoma of the head and neck (SCCHN) correlates with decreased survival rates. Computational a
Autor:
Xiang Yu Lin, Sing Han Huang, Jinn-Moon Yang, Jung Yu Lee, Yi Hsuan Chuang, Tzu Mao Hung, Wen-Sen Lai
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports
Scientific Reports
Many studies have proven the power of gene expression profile in cancer identification, however, the explosive growth of genomics data increasing needs of tools for cancer diagnosis and prognosis in high accuracy and short times. Here, we collected 6