Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Sing Yian Chew"'
Publikováno v:
Bioengineering & Translational Medicine, Vol 8, Iss 2, Pp n/a-n/a (2023)
Abstract The neuroinflammatory response that is elicited after spinal cord injury contributes to both tissue damage and reparative processes. The complex and dynamic cellular and molecular changes within the spinal cord microenvironment result in a f
Externí odkaz:
https://doaj.org/article/4936f27385c4459886a5efa599396bcb
Publikováno v:
Journal of Tissue Engineering, Vol 14 (2023)
Injury to the central nervous system (CNS) provokes an inflammatory reaction and secondary damage that result in further tissue damage and destruction of neurons away from the injury site. Upon injury, expression of connexin 43 (Cx43), a gap junction
Externí odkaz:
https://doaj.org/article/fc29ef57976a4aa6a0a467f38eb5aeeb
Autor:
Na Zhang, Ulla Milbreta, Jiah Shin Chin, Coline Pinese, Junquan Lin, Hitomi Shirahama, Wei Jiang, Hang Liu, Ruifa Mi, Ahmet Hoke, Wutian Wu, Sing Yian Chew
Publikováno v:
Advanced Science, Vol 9, Iss 14, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/f42fa187e6914ef19780535adee169c4
Autor:
Na Zhang, Junquan Lin, Jiah Shin Chin, Christian Wiraja, Chenjie Xu, Duncan Angus McGrouther, Sing Yian Chew
Publikováno v:
Journal of Tissue Engineering, Vol 13 (2022)
Injuries within the peripheral nervous system (PNS) lead to sensory and motor deficits, as well as neuropathic pain, which strongly impair the life quality of patients. Although most current PNS injury treatment approaches focus on using growth facto
Externí odkaz:
https://doaj.org/article/d1b08f3b0a434020a2516bc9cf673da3
Publikováno v:
Neural Regeneration Research, Vol 15, Iss 4, Pp 739-747 (2020)
MiR-219 and miR-338 (miR-219/miR-338) are oligodendrocyte-specific microRNAs. The overexpression of these miRs in oligodendrocyte precursor cells promotes their differentiation and maturation into oligodendrocytes, which may enhance axonal remyelinat
Externí odkaz:
https://doaj.org/article/2325957e451a439f863a2c8593a18a36
Autor:
Zhen Qiao, Hongmei Xu, Na Zhang, Xuerui Gong, Chaoyang Gong, Guang Yang, Sing Yian Chew, Changjin Huang, Yu‐Cheng Chen
Publikováno v:
Advanced Science, Vol 9, Iss 1, Pp n/a-n/a (2022)
Abstract Biological lasers which utilize Fabry–Pérot (FP) cavities have attracted tremendous interest due to their potential in amplifying subtle biological changes. Transverse laser modes generated from cells serve as distinct fingerprints of ind
Externí odkaz:
https://doaj.org/article/d0d01843886e4a949a42b8e9128645dc
Autor:
Na Zhang, Junquan Lin, Vincent Po Hen Lin, Ulla Milbreta, Jiah Shin Chin, Elaine Guo Yan Chew, Michelle Mulan Lian, Jia Nee Foo, Kunyu Zhang, Wutian Wu, Sing Yian Chew
Publikováno v:
Advanced Science, Vol 8, Iss 15, Pp n/a-n/a (2021)
Abstract Current treatment approaches toward spinal cord injuries (SCI) have mainly focused on overcoming the inhibitory microenvironment that surrounds lesion sites. Unfortunately, the mere modulation of the cell/tissue microenvironment is often ins
Externí odkaz:
https://doaj.org/article/e1cc4dbe1cf44af2a73eccdd19ee81e3
Autor:
Nicolas Marinval, Sing Yian Chew
Publikováno v:
APL Bioengineering, Vol 5, Iss 2, Pp 021505-021505-28 (2021)
Glial cells are mechanosensitive, and thus, engineered systems have taken a step forward to design mechanotransduction platforms in order to impart diverse mechanical stresses to cells. Mechanical strain encountered in the central nervous system can
Externí odkaz:
https://doaj.org/article/4e4ce380481e48139f3f3ef5888b580e
Publikováno v:
Bioengineering, Vol 9, Iss 7, p 324 (2022)
Scaffolds can promote the healing of burns and chronic skin wounds but to date have suffered from issues with achieving full skin integration. Here, we characterise the wound response by both tissue integration and re-epithelialization to a scaffold
Externí odkaz:
https://doaj.org/article/48dd28a92d704e99a387ecdd59339d7f
Publikováno v:
Journal of Tissue Engineering, Vol 11 (2020)
Drivers of RNA interference are potent for manipulating gene and protein levels, which enable the restoration of dysregulated mRNA expression that is commonly associated with injuries and diseases. This review summarizes the potential of targeting ne
Externí odkaz:
https://doaj.org/article/52d125db84b64934be2b2f62cf344cdc