Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sing Mei Lim"'
Autor:
Patthara Kongsuphol, Huan Jia, Hoi Lok Cheng, Yue Gu, Bhuvaneshwari D/O Shunmuganathan, Ming Wei Chen, Sing Mei Lim, Say Yong Ng, Paul Ananth Tambyah, Haziq Nasir, Xiaohong Gao, Dousabel Tay, Seunghyeon Kim, Rashi Gupta, Xinlei Qian, Mary M. Kozma, Kiren Purushotorman, Megan E. McBee, Paul A. MacAry, Hadley D. Sikes, Peter R. Preiser
Publikováno v:
Communications Medicine, Vol 1, Iss 1, Pp 1-12 (2021)
Kongsuphol et al. develop a paper-based, vertical flow assay to detect SARS-CoV-2 neutralizing antibodies. The point-of-care assay has comparable performance to lab-based tests and provides results in 10 min.
Externí odkaz:
https://doaj.org/article/663f8b27aead4a418e60988c13e46a00
Autor:
Hoi Lok Cheng, Sing Mei Lim, Huan Jia, Ming Wei Chen, Say Yong Ng, Xiaohong Gao, Jyoti Somani, Sharmila Sengupta, Dousabel M. Y. Tay, Patrina W. L. Chua, Abirami R., Sharon Y. H. Ling, Megan E. McBee, Barnaby E. Young, Hadley D. Sikes, Peter R. Preiser
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 5 (2022)
ABSTRACT As the COVID-19 pandemic continues, countries around the world are switching toward vaccinations and boosters to combat the pandemic. However, waning immunity against SARS-CoV-2 wild-type (WT) and variants have been widely reported. Booster
Externí odkaz:
https://doaj.org/article/6651f04433e54122ae0f8bff3b6af7b6
Autor:
Sing Mei Lim, Hoi Lok Cheng, Huan Jia, Patthara Kongsuphol, Bhuvaneshwari D/O Shunmuganathan, Ming Wei Chen, Say Yong Ng, Xiaohong Gao, Shuvan Prashant Turaga, Sascha P. Heussler, Jyoti Somani, Sharmila Sengupta, Dousabel M. Y. Tay, Megan E. McBee, Barnaby E. Young, Paul A. MacAry, Hadley D. Sikes, Peter R. Preiser
Publikováno v:
Bioengineering & Translational Medicine, Vol 7, Iss 2, Pp n/a-n/a (2022)
Abstract There is clinical need for a quantifiable point‐of‐care (PoC) SARS‐CoV‐2 neutralizing antibody (nAb) test that is adaptable with the pandemic's changing landscape. Here, we present a rapid and semi‐quantitative nAb test that uses f
Externí odkaz:
https://doaj.org/article/d63c818224ae4a54916797daab64c017
Autor:
Sing Mei Lim, Dan Chen, Hsiangling Teo, Annette Roos, Anna Elisabet Jansson, Tomas Nyman, Lionel Trésaugues, Konstantin Pervushin, Pär Nordlund
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 6, Pp 1630-1643 (2013)
Lipocalin prostaglandin D synthase (L-PGDS) regulates synthesis of an important inflammatory and signaling mediator, prostaglandin D2 (PGD2). Here, we used structural, biophysical, and biochemical approaches to address the mechanistic aspects of subs
Externí odkaz:
https://doaj.org/article/0ddb8b505cf44eb0bab1028ca8d32f8e
Autor:
Huan Jia, Eric A. Miller, Chia Ching Chan, Say Yong Ng, Mookkan Prabakaran, Meng Tao, Ian Shen-Yi Cheong, Sing Mei Lim, Ming Wei Chen, Xiaohong Gao, Abirami R., Megan E. McBee, Peter R. Preiser, Hadley D. Sikes, Patthara Kongsuphol
Publikováno v:
Lab on a Chip. 22:1321-1332
Surveillance of SARS-CoV-2 infection is critical for controlling the current pandemic. Antigen rapid tests (ARTs) provide a means for surveillance. Available lateral flow assay format ARTs rely heavily on nitrocellulose paper, raising challenges in s
Autor:
Hoi Lok Cheng, Peter R. Preiser, O Shunmuganathan, Hadley D. Sikes, Haziq Nasir, Patthara Kongsuphol, Mary M Kozma, Paul Ananth Tambyah, Bhuvaneshwari D, Megan E. McBee, Seunghyeon Kim, Xiaohong Gao, Say Yong Ng, Paul A. MacAry, Dousabel M Y Tay, Kiren Purushotorman, Rashi Gupta, Sing Mei Lim, Huan Jia, Xinlei Qian, Yue Gu, Ming Wei Chen
Publikováno v:
Communications Medicine, Vol 1, Iss 1, Pp 1-12 (2021)
Neutralizing antibodies (NAbs) prevent pathogens from infecting host cells. Detection of SARS-CoV-2 NAbs is critical to evaluate herd immunity and monitor vaccine efficacy against SARS-CoV-2, the virus that causes COVID-19. All currently available NA
Autor:
Sing Mei Lim, Hoi Lok Cheng, Huan Jia, Patthara Kongsuphol, Bhuvaneshwari D/O Shunmuganathan, Ming Wei Chen, Say Yong Ng, Xiaohong Gao, Shuvan Prashant Turaga, Sascha P. Heussler, Jyoti Somani, Sharmila Sengupta, Dousabel M. Y. Tay, Megan E. McBee, Barnaby E. Young, Paul A. MacAry, Hadley D. Sikes, Peter R. Preiser
Publikováno v:
Bioengineeringtranslational medicine. 7(2)
There is clinical need for a quantifiable point-of-care (PoC) SARS-CoV-2 neutralizing antibody (nAb) test that is adaptable with the pandemic's changing landscape. Here, we present a rapid and semi-quantitative nAb test that uses finger stick or veno
Publikováno v:
Structure
The nuclear position in eukaryotic cells is controlled by a nucleo-cytoskeletal network, with important roles in cell differentiation, division and movement. Forces are transmitted through conserved linker of nucleoskeleton and cytoskeleton (LINC) co
Publikováno v:
FEBS Journal. 283:1107-1123
Human sphingomyelinase phosphodiesterase like 3a (SMPDL3a) is a secreted enzyme that shares a conserved catalytic domain with human acid sphingomyelinase (aSMase), the enzyme carrying mutations causative of Niemann–Pick disease. We have solved the
Autor:
Pär Nordlund, Tomas Nyman, Sing Mei Lim, Konstantin Pervushin, Annette Roos, Anna Elisabet Jansson, Hsiangling Teo, Dan Chen, Lionel Trésaugues
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 6, Pp 1630-1643 (2013)
Lipocalin prostaglandin D synthase (L-PGDS) regulates synthesis of an important inflammatory and signaling mediator, prostaglandin D2 (PGD2). Here, we used structural, biophysical, and biochemical approaches to address the mechanistic aspects of subs