Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Sinem Karaman"'
Autor:
Sofiia Rybas, Sinem Karaman, Kevin Aguilar, Lina Smeds, Johan Westö, Anna Ribeiro Xavier, Maiken Nedergaard, Albert Quintana, Juan Hidalgo Hidalgo, Petri Ala-Laurila, Kari Alitalo, Gulayse Ince Dunn, Anu Suomalainen
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S638- (2023)
Externí odkaz:
https://doaj.org/article/816b66c05e544dbd810e016c69f69fda
Publikováno v:
STAR Protocols, Vol 4, Iss 2, Pp 102310- (2023)
Summary: The small intestine is an excellent model for studying changes in vasculature in response to different diseases or gene deletions. Here, we present a protocol for whole-mount immunofluorescence staining of blood and lymphatic vessels in the
Externí odkaz:
https://doaj.org/article/e5540c15ffd148a0bd97a383b2e8518e
Autor:
Cristina C. Clement, Angelo D’Alessandro, Sangeetha Thangaswamy, Samantha Chalmers, Raquel Furtado, Sheila Spada, Giada Mondanelli, Federica Ianni, Sarah Gehrke, Marco Gargaro, Giorgia Manni, Luisa Carlota Lopez Cara, Peter Runge, Wanxia Li Tsai, Sinem Karaman, Jorge Arasa, Ruben Fernandez-Rodriguez, Amanda Beck, Antonio Macchiarulo, Massimo Gadina, Cornelia Halin, Francesca Fallarino, Mihaela Skobe, Marc Veldhoen, Simone Moretti, Silvia Formenti, Sandra Demaria, Rajesh K. Soni, Roberta Galarini, Roccaldo Sardella, Gregoire Lauvau, Chaim Putterman, Kari Alitalo, Ursula Grohmann, Laura Santambrogio
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
3-hydroxy-L-kynurenamine (3-HKA) is a metabolite deriving from a lateral pathway of tryptophan catabolism. Here the authors identify 3-HKA as a biogenic amine and show it has anti-inflammatory properties that can protect mice against psoriasis and ne
Externí odkaz:
https://doaj.org/article/95a6bc7fc7a345f08d833daae479ee94
Autor:
Sun-Young Yoon, Lothar C Dieterich, Sinem Karaman, Steven T Proulx, Samia B Bachmann, Carol Sciaroni, Michael Detmar
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0220341 (2019)
The lymphatic vascular system plays important roles in the control of tissue fluid homeostasis and immune responses. While VEGF-A-induced angiogenesis promotes hair follicle (HF) growth, the potential role of lymphatic vessels (LVs) in HF cycling has
Externí odkaz:
https://doaj.org/article/2c855776b6a54fb6aa736f7fdfafa86d
Publikováno v:
Cells, Vol 9, Iss 12, p 2683 (2020)
Obesity and its comorbidities like diabetes, hypertension and other cardiovascular disorders are the leading causes of death and disability worldwide. Metabolic diseases cause vascular dysfunction and loss of capillaries termed capillary rarefaction.
Externí odkaz:
https://doaj.org/article/ebfbdfb989d9451eb068e70117f33b11
Autor:
Katrin S Blum, Sinem Karaman, Steven T Proulx, Alexandra M Ochsenbein, Paola Luciani, Jean-Christophe Leroux, Christian Wolfrum, Michael Detmar
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94713 (2014)
Lymphatic vessels play an essential role in intestinal lipid uptake, and impairment of lymphatic vessel function leads to enhanced adipose tissue accumulation in patients with lymphedema and in genetic mouse models of lymphatic dysfunction. However,
Externí odkaz:
https://doaj.org/article/7baad07cb68148a7a2f2c73f584562a3
Autor:
Andrey Anisimov, Shentong Fang, Karthik Amudhala Hemanthakumar, Tiit Örd, Kristof van Avondt, Raphael Chevre, Anu Toropainen, Prosanta Singha, Huda Gilani, Su D. Nguyen, Sinem Karaman, Emilia A. Korhonen, Ralf H. Adams, Hellmut G. Augustin, Katariina Öörni, Oliver Soehnlein, Minna U. Kaikkonen, Kari Alitalo
Publikováno v:
Nature Cardiovascular Research. 2:307-321
Leukocytes and resident cells in the arterial wall contribute to atherosclerosis, especially at sites of disturbed blood flow. Expression of endothelial Tie1 receptor tyrosine kinase is enhanced at these sites, and attenuation of its expression reduc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aa11707359131185bee4b27b0aa7ffc
https://doi.org/10.1038/s44161-023-00224-y
https://doi.org/10.1038/s44161-023-00224-y
Autor:
Jenna H. Rannikko, Loic Verlingue, Maria de Miguel, Annika Pasanen, Debbie Robbrecht, Tanja Skytta, Sanna Iivanainen, Shishir Shetty, Yuk Ting Ma, Donna M. Graham, Sukeshi Patel Arora, Panu Jaakkola, Christina Yap, Yujuan Xiang, Jami Mandelin, Matti K. Karvonen, Juho Jalkanen, Sinem Karaman, Jussi P. Koivunen, Anna Minchom, Maija Hollmén, Petri Bono
Clever-1 expression in macrophages contributes to impaired antigen presentation and suppression of anti-tumor immunity. This first-in-human trial was designed to investigate the safety and tolerability of Clever-1 blockade in patients with treatment-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68b8cb2572a9a06baf7e29b63bb2c665
https://doi.org/10.1101/2023.04.17.23288693
https://doi.org/10.1101/2023.04.17.23288693
Autor:
Michael Detmar, Maija Bry, Nicole Schneider, Manuela Jost, Stefania Martino, David Aebischer, Sinem Karaman, Steven T. Proulx, Annamari K. Alitalo
PDF - 120K.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba03ee379c39c3940f0f0f5c6c006018
https://doi.org/10.1158/0008-5472.22397033.v1
https://doi.org/10.1158/0008-5472.22397033.v1
Autor:
Michael Detmar, Maija Bry, Nicole Schneider, Manuela Jost, Stefania Martino, David Aebischer, Sinem Karaman, Steven T. Proulx, Annamari K. Alitalo
PDF - 1898K, Expression of neuropilins in skin and tumors of wild-type mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fe1ca870eb88d200c4bc0da39de31f1
https://doi.org/10.1158/0008-5472.22397036
https://doi.org/10.1158/0008-5472.22397036