Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Sinead T Aherne"'
Autor:
Fiona O'Neill, Martin Clynes, Finbarr O'Sullivan, Karina Horgan, Michael Henry, Joanne Keenan, Padraig Doolan, Paula Meleady, Richard Murphy, Niall Barron, Sinead T Aherne, Laura Breen, Colin Clarke
Publikováno v:
World Journal of Gastroenterology
AIM To identify miRNA-regulated proteins differentially expressed between Caco2 and HT-29: two principal cell line models of the intestine. METHODS Exponentially growing Caco-2 and HT-29 cells were harvested and prepared for mRNA, miRNA and proteomic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea39ecc2966b0c4000e4414f00956ac5
https://doi.org/10.3748/wjg.v23.i41.7369
https://doi.org/10.3748/wjg.v23.i41.7369
Publikováno v:
Cancer Research. 75:P4-07
HER2 positive breast cancer accounts for approximately 20-25 % of breast cancers. Trastuzumab, a humanised monoclonal antibody, is approved for the treatment of HER2 positive breast cancer. However, the majority of metastatic HER2 positive breast can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44d9b6ded5175b58ad25c25a971448ec
https://doi.org/10.1158/1538-7445.sabcs14-p4-07-06
https://doi.org/10.1158/1538-7445.sabcs14-p4-07-06
Autor:
Maria Prencipe, Martin Clynes, Amanda O'Neill, Dara Lundon, R.W. Watson, Elaine W. Kay, G. Hurley, Sinead T Aherne, John M. Fitzpatrick, A. Boland, Colm Morrissey, Padraig Doolan, Stephen F. Madden
Publikováno v:
BMC Cancer
Background Docetaxel based therapy is one of the first line chemotherapeutic agents for the treatment of metastatic castrate-resistant prostate cancer. However, one of the major obstacles in the treatment of these patients is docetaxel-resistance. De
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4359c3206a6ae75bf2c985cf8caba036
http://europepmc.org/articles/PMC5333466
http://europepmc.org/articles/PMC5333466
Autor:
Colin Clarke, Laura Breen, Mark Leonard, Niall Barron, Sinead T Aherne, Paula Kinsella, Paula Meleady, Padraig Doolan, Martin Clynes, Lin Zhang
Publikováno v:
Journal of Biotechnology. 166:105-113
The selection of clones displaying a high rate of cell growth is an essential component of Chinese hamster ovary (CHO) cell line development. In recent years various "omics" technologies have been utilised to understand the mechanisms underlying biop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4401a82451ca09daa54e1131b3158817
https://doi.org/10.1016/j.jbiotec.2013.04.014
https://doi.org/10.1016/j.jbiotec.2013.04.014
Autor:
Sinead T Aherne, Nga T. Lao
Publikováno v:
Methods in Molecular Biology ISBN: 9781493965229
There are a numerous target prediction algorithms that allow users to identify putative targets of their microRNAs (miRNAs) of interest. Although these tools are useful to gain insight into the potential role of miRNAs in regulating cellular processe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d117de75011b9ccf5e0b006857f58ec
https://doi.org/10.1007/978-1-4939-6524-3_14
https://doi.org/10.1007/978-1-4939-6524-3_14
Autor:
Alexandros Laios, Kai Q Lao, Salah A Elbaruni, Michael F Gallagher, Yvonne M Salley, Cara Martin, K Denning, Richard Flavin, Paul Smyth, Sebastian Vencken, John J. O'Leary, Sinead T Aherne, Sharon O'Toole, J Li, Jamie McInerney, Mathia Yc Lee, Orla Sheils
Publikováno v:
Journal of Ovarian Research
Journal of Ovarian Research, Vol 2, Iss 1, p 19 (2009)
Journal of Ovarian Research, Vol 2, Iss 1, p 19 (2009)
Background Tumours with high proportions of differentiated cells are considered to be of a lower grade to those containing high proportions of undifferentiated cells. This property may be linked to the differentiation properties of stem cell-like pop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a27882ad0083091febf7dfe71a5dfed6
https://doi.org/10.1186/1757-2215-2-19
https://doi.org/10.1186/1757-2215-2-19
Autor:
K Denning, John J O' Leary, Orla Sheils, J Li, Richard Flavin, Sinead T Aherne, S. Cahill, Paul Smyth
Publikováno v:
Molecular Cancer, Vol 7, Iss 1, p 44 (2008)
Molecular Cancer
Molecular Cancer
Background Hashimoto Thyroiditis (H.T.) is a destructive autoimmune thyroid condition whose precise molecular pathogenesis remains unclear. ret/PTC-1 is a chimeric transcript which has been described in autoimmune thyroid disease (AITD) and thyroid n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eacc99114e276147004d983d53e111fb
https://ora.ox.ac.uk/objects/uuid:06bd0850-a321-447d-9334-f710059c6a36
https://ora.ox.ac.uk/objects/uuid:06bd0850-a321-447d-9334-f710059c6a36
Autor:
Helena Joyce, Padraig Doolan, Joanne Keenan, Martin Clynes, Vincent J. Lynch, Shirley O'Dea, Sinead T Aherne
Publikováno v:
Experimental Cell Research. 318:593-602
Three clonal subpopulations of DLKP, a poorly differentiated squamous lung carcinoma cell line, display striking differences in ability to survive in suspension (anoikis resistance). DLKP-SQ is anoikis resistant (7.5% anoikis at 24 h). In contrast, D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa53ff469be3f4d490441230f28655a3
https://doi.org/10.1016/j.yexcr.2012.01.012
https://doi.org/10.1016/j.yexcr.2012.01.012
Autor:
Alexandros Laios, Stephen P. Finn, Ciara Barrett, Natasha A Aziz, K Denning, J Li, Orla Sheils, John J. O'Leary, M Ring, Sinead T Aherne, Araibi Alhadi, Paul Smyth, Brian L. Sheppard, Richard Flavin, Sharon O'Toole, Cara Martin, Massimo Loda
Publikováno v:
Modern Pathology. 21:676-684
MicroRNAs are a group of small non-coding RNAs approximately 22 nucleotides in length. Recent work has shown differential expression of mature microRNAs in human cancers. Production and function of microRNAs require coordinated processing by proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aad4f91c4e0539484ec706d6f626b1e
https://doi.org/10.1038/modpathol.2008.33
https://doi.org/10.1038/modpathol.2008.33
Autor:
Alberto Benito-Martin, Harry Holthöfer, Tataruch Dorota Ewa, Giulio Calzaferri, Sinead T Aherne, Dongfeng Gu, Luca Musante
Publikováno v:
Scientific Reports
Urinary extracellular vesicles provide a novel source for valuable biomarkers for kidney and urogenital diseases: Current isolation protocols include laborious, sequential centrifugation steps which hampers their widespread research and clinical use.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::708b994ffb90d96e2eec977c4bf6e61f
https://pubmed.ncbi.nlm.nih.gov/25532487
https://pubmed.ncbi.nlm.nih.gov/25532487