Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Sinead King"'
Autor:
Sinead King, David Mothersill, Laurena Holleran, Saahithh Redddi Patlola, Tom Burke, Ross McManus, Marcus Kenyon, Colm McDonald, Brian Hallahan, Aiden Corvin, Derek W. Morris, John P. Kelly, Declan P. McKernan, Gary Donohoe
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-7 (2023)
Abstract Childhood trauma (CT) is associated with lower cognitive and social cognitive function in schizophrenia. Recent evidence suggests that the relationship between CT and cognition is mediated by both low-grade systemic inflammation and reduced
Externí odkaz:
https://doaj.org/article/17c375194589468c9b8d64ca5de505dc
Autor:
Sinead King, David Mothersill, Laurena Holleran, Saahithh Patlola, Ross McManus, Marcus Kenyon, Colm McDonald, Brian Hallahan, Aiden Corvin, Derek W. Morris, John P. Kelly, Declan McKernan, Gary Donohoe
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 26, Iss , Pp 100540- (2022)
Background: Both low-grade systemic inflammation and functional connectivity of the default mode network (DMN) during rest have recently been observed to mediate the association between childhood trauma (CT) and behavioural performance on an emotion
Externí odkaz:
https://doaj.org/article/26131da1ff9740668f59cfa425877851
Autor:
Luke A. Jelen, Mark S. Green, Sinead King, Alex G. Morris, Xinyuan Zhang, David J. Lythgoe, Allan H. Young, Jacqueline De Belleroche, James M. Stone
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
Zinc transporter 3 (ZnT3) has been implicated in the aetiopathology of schizophrenia. In this pilot study, we tested the hypothesis that the presence of a minor allele of two variants in the gene encoding ZnT3 (SLC30A3) affects brain glutamate and co
Externí odkaz:
https://doaj.org/article/2cc819688fbf4356b1a90867bc17a0f1
Autor:
David Mothersill, Sinead King, Laurena Holleran, Maria Dauvermann, Saahithh Patlola, Karolina Rokita, Ross McManus, Marcus Keynon, Colm McDonald, Brian Hallahan, Aiden Corvin, Derek Morris, John Kelly, Declan McKernan, Gary Donohoe
Publikováno v:
NeuroImage: Clinical, Vol 32, Iss , Pp 102851- (2021)
Background: Deficits in facial emotion recognition are a core feature of schizophrenia and predictive of functional outcome. Higher plasma levels of the cytokine interleukin 6 (IL-6) have recently been associated with poorer facial emotion recognitio
Externí odkaz:
https://doaj.org/article/57fe77196ce344b09b892c402a2407c7
Autor:
Sinead King, Luke A. Jelen, Charlotte M. Horne, Anthony Cleare, Carmine M. Pariante, Allan H. Young, James M. Stone
Publikováno v:
Frontiers in Psychiatry, Vol 10 (2019)
Background: Two current theories regarding the neuroscientific bases of mood disorders involve alterations in glutamatergic neurotransmission and excessive activation of inflammatory pathways. We hypothesized that glutamate (Glu) levels and periphera
Externí odkaz:
https://doaj.org/article/0bea22296ba1488ba4844f14e3477e19
Autor:
Rebecca Strawbridge, Lindsey Marwood, Sinead King, Allan H. Young, Carmine M. Pariante, Alessandro Colasanti, Anthony J. Cleare
Publikováno v:
Journal of Clinical Medicine, Vol 9, Iss 12, p 3918 (2020)
In people with depression, immune dysfunctions have been linked with treatment non-response, but examinations of psychological therapy outcomes, particularly longitudinal biomarker studies, are rare. This study investigated relationships between infl
Externí odkaz:
https://doaj.org/article/f517736a865c41c98cd9d933743857e3
Autor:
Naushaba Khan, Charles DeBattista, Keith Sudheimer, Clive Veerapal, Angela Phillips, Azeezat Azeez, James Bishop, Kirsten Cherian, Romina Nejad, Booil Jo, Jennifer Keller, John P. Coetzee, David Carreon, Brandon S. Bentzley, Maureen Chang, Rachel Rapier, Elizabeth Choi, Emily Felber, Nolan R. Williams, Jessica Hawkins, Randi Brown, Sinead King, Kristin S. Raj, Alan F. Schatzberg, Katy H. Stimpson, Flint M. Espil, E. Cole, Heather Pankow, Nicole Odenwald, Fahim Barmak
Publikováno v:
American Journal of Psychiatry. 179:132-141
Depression is the leading cause of disability worldwide, and half of patients with depression have treatment-resistant depression. Intermittent theta-burst stimulation (iTBS) is approved by the U.S. Food and Drug Administration for the treatment of t
Autor:
John V. Reynolds, Noel E. Donlon, Jessie A. Elliott, Brendan Moran, Hugo Temperley, Tim S. Nugent, Maria Davern, Sinead King, Melissa Conroy, Joanne Lysaght, Narayanasamy Ravi, Carmel Ryan, Stephen Finn, Suzanne Norris, Clare L. Donohoe
Publikováno v:
World journal of surgery. 47(1)
Esophageal adenocarcinoma (EAC) is associated with visceral obesity (VO). Non-alcoholic fatty liver disease (NAFLD) is common within this phenotype; however, its incidence and clinical significance in EAC have not been studied.A total of 559 patients
Autor:
Jonathan Cools-Lartigue, Maeve A. Lowery, Alexander W. Phillips, Narayanasamy Ravi, John V. Reynolds, Jakub Chmelo, Anitha Kammili, Lorenzo E. Ferri, Sinead King, Maria Davern, Claire L. Donohoe, Carmen L. Mueller, Noel Edward Donlon, Ryan Roopnarinesingh, Robert Power
Publikováno v:
Annals of Surgery. 274:814-820
BACKGROUND AND AIMS The FLOT4-AIO trial established the FLOT regimen as a compelling option for gastric, junctional and esophageal adenocarcinoma. Data on FLOT with en-bloc transthoracic esophagectomy (TTE) are limited. This study explored operative
Autor:
Noel E. Donlon, Brendan Moran, Anitha Kamilli, Maria Davern, Andrew Sheppard, Sinead King, Claire L. Donohoe, Maeve Lowery, Moya Cunningham, Narayanasamy Ravi, Carmen Mueller, Jonathan Cools-Lartigue, Lorenzo Ferri, John V. Reynolds
Publikováno v:
Annals of surgery. 276(5)
The FLOT protocol and the CROSS trimodality regimen represent current standards in the management of locally advanced esophageal adenocarcinoma. In the absence of published Randomised Controlled Trial data, this propensity-matched comparison evaluate