Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Sinead Cocchiglia"'
Autor:
Leonie S. Young, Arnold D.K. Hill, Paul Tibbitts, Jane O'Hara, Stephen Sande, Sinead Cocchiglia, Eamon Hughes, Christopher Byrne, Sarah M. Theissen, Jean McBryan
PDF file - 154K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08102f2cac0a8def2ec828d977521b4d
https://doi.org/10.1158/0008-5472.22392138
https://doi.org/10.1158/0008-5472.22392138
Autor:
Leonie S. Young, Arnold D.K. Hill, Paul Tibbitts, Jane O'Hara, Stephen Sande, Sinead Cocchiglia, Eamon Hughes, Christopher Byrne, Sarah M. Theissen, Jean McBryan
PDF file - 28K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeab987c3cf19002ae0210978529fb78
https://doi.org/10.1158/0008-5472.22392135.v1
https://doi.org/10.1158/0008-5472.22392135.v1
Autor:
Leonie S. Young, Arnold D.K. Hill, Paul Tibbitts, Jane O'Hara, Stephen Sande, Sinead Cocchiglia, Eamon Hughes, Christopher Byrne, Sarah M. Theissen, Jean McBryan
PDF file - 175K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40785d4370a41c568de9973a11f95757
https://doi.org/10.1158/0008-5472.22392144.v1
https://doi.org/10.1158/0008-5472.22392144.v1
Autor:
Stephen Keelan, Fiona T Bane, Leonie S. Young, Sara Charmsaz, Damir Varešlija, Sinead Cocchiglia, Siobhan Purcell, A Hill
Publikováno v:
British Journal of Surgery. 108
Introduction Brain metastasis (BrM) occurs in 10-30% of patients with advanced breast cancer (BC). BrM is increasing in incidence and confers a poor prognosis. We aimed to investigate the contribution of global epi-transcriptomic alterations in N6-me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4157b4aadd1015610305a719ad974f7
https://doi.org/10.1093/bjs/znab117.028
https://doi.org/10.1093/bjs/znab117.028
Autor:
Nicola Cosgrove, Michael Flanagan, Katherine M. Sheehan, Sinead Cocchiglia, Leonie S. Young, Siobhan Purcell, Fiona T Bane, D Varšlija, A Hill, Sara Charmsaz
Publikováno v:
British Journal of Surgery. 108
Introduction Therapeutic pressure functionally affects oncogenes and related signalling pathways through dynamic alterations in transcriptional and epigenetic alterations. Altered receptor status occurs throughout tumour progression and may be influe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71666df1732c2fb6cbb4a5b7896adebd
https://doi.org/10.1093/bjs/znab117.012
https://doi.org/10.1093/bjs/znab117.012
Autor:
Francesca Brett, Lance Hudson, P Jagust, Sinead Cocchiglia, Leonie S. Young, Damir Varešlija, Jane Cryan, A Hill, MO Dablouk, PJ O'Haloran, Alan Beausang
Publikováno v:
British Journal of Surgery. 108
Introduction Metastatic breast cancer (MBC) is the main source of mortality in breast cancer patients largely due to lack of effective treatments. Our previous results suggest that tumour transcriptional heterogeneity drives therapy resistance and ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2a3bcbdd77bd7653126785d8c3228db
https://doi.org/10.1093/bjs/znab117.050
https://doi.org/10.1093/bjs/znab117.050
Autor:
Jane Cryan, Siobhan Purcell, Andrew H. Sims, Philip J. O’Halloran, Francesca Brett, Adrian V. Lee, Arran K Turnbul, Fiona T Bane, Lance Hudson, Jason S. Carroll, Elspeth Ward, Nolan Priedigkeit, Leonie S. Young, J Michael Dixon, Steffi Oesterreich, Nicola Cosgrove, Damir Varešlija, Sinead Cocchiglia, Michael Farrell, Arnold D.K. Hill, Aisling M. Redmond, Alan Beausang, Sara Charmsaz
Publikováno v:
Oncogene
Funder: Breast Cancer Ireland GR 14-0883
Steroid regulated cancer cells use nuclear receptors and associated regulatory proteins to orchestrate transcriptional networks to drive disease progression. In primary breast cancer, the coactivator AIB1
Steroid regulated cancer cells use nuclear receptors and associated regulatory proteins to orchestrate transcriptional networks to drive disease progression. In primary breast cancer, the coactivator AIB1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0111a9662b377268b9f7017dcc77bb1
https://www.repository.cam.ac.uk/handle/1810/316206
https://www.repository.cam.ac.uk/handle/1810/316206
Autor:
Stephen Keelan, Mihaela Ola, Sara Charmsaz, Sinead Cocchiglia, Karen Crowley, Siobhan Purcell, Fiona Bane, Aisling Hegarty, Ben Doherty, Katherine Sheehan, Lance Hudson, Nicola Cosgrove, Benjamin Roux, Muriel Laine, Geoffrey Greene, Damir Vareslija, Arnold Hill, Leonie Young
Publikováno v:
Mesentery and Peritoneum. 6:AB069-AB069
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4423b63a5b7935c2757c243338200b64
https://doi.org/10.21037/map-22-ab069
https://doi.org/10.21037/map-22-ab069
Autor:
Matteo Battaglini, Chiara Martinelli, Adrian V. Lee, Arnold D.K. Hill, Fiona T Bane, Stephen F. Madden, Siobhan Purcell, Katherine M. Sheehan, Ricardo Marques, Francesca Brett, Attilio Marino, Gianni Ciofani, Stephen Keelan, Kieran Brennan, Sara Charmsaz, Christopher Byrne, Jarlath C. Bolger, Sinead Cocchiglia, Ben Doherty, Ann M. Hopkins, Petra Jagust, Damir Varešlija, Nicola Cosgrove, Nolan Priedigkeit, Leonie S. Young, Philip J. O’Halloran, Steffi Oesterreich
Publikováno v:
BMC Medicine
BMC Medicine, Vol 18, Iss 1, Pp 1-14 (2020)
BMC Medicine, Vol 18, Iss 1, Pp 1-14 (2020)
Background Metastatic breast cancer is a major cause of cancer-related deaths in woman. Brain metastasis is a common and devastating site of relapse for several breast cancer molecular subtypes, including oestrogen receptor-positive disease, with lif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::306c4abaf3b97fa5d03fb3f2e853fb78
http://hdl.handle.net/11311/1204442
http://hdl.handle.net/11311/1204442
Autor:
Roisin M. Dwyer, Paul Tibbitts, Christopher Byrne, Leonie S. Young, Arnold D.K. Hill, Sinead Cocchiglia, Sara Charmsaz, Bryan T. Hennessy, E Hughes, Fiona T Bane, Jean McBryan, Marie McIlroy, Michael J. Kerin
Publikováno v:
BMC Medicine, Vol 15, Iss 1, Pp 1-12 (2017)
BMC Medicine
BMC Medicine
Background Endocrine therapy is standard treatment for estrogen receptor (ER)-positive breast cancer. However, its efficacy is limited by intrinsic and acquired resistance. Here the potential of S100β as a biomarker and inhibition of its signaling n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6d50e29f7b10b78197b0ea98e2c4e22
http://link.springer.com/article/10.1186/s12916-017-0836-2
http://link.springer.com/article/10.1186/s12916-017-0836-2