Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sindhu Thangavel"'
Publikováno v:
Biomaterials. 99:109-123
Pioglitazone is a widely used anti-diabetic drug that induces cytotoxicity in cancer cells; however, its clinical use is questioned due to its associated liver toxicity caused by increased oxidative stress. We therefore employed nitroxide-radical con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7af49568bb0ced1e72e18697f2da4ea
https://doi.org/10.1016/j.biomaterials.2016.05.001
https://doi.org/10.1016/j.biomaterials.2016.05.001
Publikováno v:
Journal of Controlled Release. 209:110-119
Curcumin is a phytochemical with diverse molecular targets and is well known for its anti-tumor potential. However, it has limited application in cancer therapy because curcumin undergoes rapid oxidative degradation at physiological conditions result
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce4a351e44b37caea5c513697e80c067
https://doi.org/10.1016/j.jconrel.2015.04.025
https://doi.org/10.1016/j.jconrel.2015.04.025
Autor:
Alan Prem Kumar, Kishore R. Sakharkar, Meena Kishore Sakharkar, Sindhu Thangavel, Gireedhar Venkatachalam, Marie-Veronique Clement
Publikováno v:
Journal of Drug Targeting. 19:781-796
Peroxisome proliferator-activated receptor (PPAR) belongs to the nuclear hormone receptor superfamily. Recently published reports demonstrate the importance of a direct repeat 2 (DR2) as a PPARγ-responsive element in addition to the canonical direct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9924db00822a3e9933c43a472397e0d
https://doi.org/10.3109/1061186x.2011.568062
https://doi.org/10.3109/1061186x.2011.568062
Autor:
Ryszard Krzyminiewski, Magdalena Hałupka-Bryl, Sindhu Thangavel, Kei Asai, Magdalena Bednarowicz, Yukio Nagasaki
Publikováno v:
Colloids and surfaces. B, Biointerfaces. 118
The main challenge in antitumor chemotherapy is to enhance the curative effect and minimize the adverse effects of an anticancer drug. Administration of functionalized magnetic iron oxide nanoparticles is one of the strategies to improve sensitivity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88b91552881b3572ce92031a9f9024df
https://pubmed.ncbi.nlm.nih.gov/24769390
https://pubmed.ncbi.nlm.nih.gov/24769390
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 172(1)
The ultimate goal of cancer chemotherapy is to achieve a cure without causing any adverse effects. We have developed a pH-sensitive redox nanoparticle (RNP N ), which disintegrates under acidic conditions and exposes nitroxide radicals, leading to st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3062d084743dcc1b1a4e6336e5adc8f6
https://pubmed.ncbi.nlm.nih.gov/23958903
https://pubmed.ncbi.nlm.nih.gov/23958903