Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Sindhu Chandran"'
Autor:
Meixue Duan, Doan C. Nguyen, Chester J. Joyner, Celia L. Saney, Christopher M. Tipton, Joel Andrews, Sagar Lonial, Caroline Kim, Ian Hentenaar, Astrid Kosters, Eliver Ghosn, Annette Jackson, Stuart Knechtle, Stalinraja Maruthamuthu, Sindhu Chandran, Tom Martin, Raja Rajalingam, Flavio Vincenti, Cynthia Breeden, Ignacio Sanz, Greg Gibson, F. Eun-Hyung Lee
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112682- (2023)
Summary: Human bone marrow (BM) plasma cells are heterogeneous, ranging from newly arrived antibody-secreting cells (ASCs) to long-lived plasma cells (LLPCs). We provide single-cell transcriptional resolution of 17,347 BM ASCs from five healthy adult
Externí odkaz:
https://doaj.org/article/e2cfa9f8c92144a5ae6fadda3ba129f7
Autor:
Michelle F. Huffaker, Srinath Sanda, Sindhu Chandran, Sharon A. Chung, E. William St. Clair, Gerald T. Nepom, Dawn E. Smilek
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The development of rational approaches to restore immune tolerance requires an iterative approach that builds on past success and utilizes new mechanistic insights into immune-mediated pathologies. This article will review concepts that have evolved
Externí odkaz:
https://doaj.org/article/456ffed289e8483883fd5f8b1dd4ad4a
Autor:
Arya Zarinsefat, George Hartoularos, Dmitry Rychkov, Priyanka Rashmi, Sindhu Chandran, Flavio Vincenti, Chun J. Yee, Minnie M. Sarwal
Publikováno v:
Frontiers in Genetics, Vol 11 (2021)
COVID-19 has posed a significant threat to global health. Early data has revealed that IL-6, a key regulatory cytokine, plays an important role in the cytokine storm of COVID-19. Multiple trials are therefore looking at the effects of Tocilizumab, an
Externí odkaz:
https://doaj.org/article/3ee169dd4d724d3ca6bf4ec925b76bdc
Autor:
Benjamin J. Lee, MD, Charles E. McCulloch, PhD, Barbara A. Grimes, PhD, Sindhu Chandran, MD, Isabel Elaine Allen, PhD, Cynthia Delgado, MD, Chi-yuan Hsu, MD, MSc
Publikováno v:
Transplantation Direct, Vol 3, Iss 8, p e195 (2017)
Background. Earlier qualification for the kidney transplant waitlist expedites transplant and is therefore associated with improved outcomes. U.S. Organ Procurement and Transplantation Network policies state that “measured or calculated creatinine
Externí odkaz:
https://doaj.org/article/3378b708c2e64a739b5700b85eb5c043
Publikováno v:
Journal of Transplantation, Vol 2014 (2014)
Background. BK virus (BKV) infection is a common complication following kidney transplantation. Immunosuppression reduction is the cornerstone of treatment while adjuvant drugs have been tried in small uncontrolled studies. We sought to examine our c
Externí odkaz:
https://doaj.org/article/1f4524839ca44e0eab6f7410f4b9041f
Autor:
Megan Sykes, Sindhu Chandran, Tatsuo Kawai, Josh Levitsky, Markus Mapara, James Mathew, Angus Thomson, Kazuhiko Yamada
Publikováno v:
Transplantation. 107:564-569
Autor:
Qizhi Tang, Sindhu Chandran
Publikováno v:
American Journal of Transplantation. 22:18-27
Interleukin-6 (IL-6), a multifunctional proinflammatory cytokine, plays a key role in T cell activation, survival, and differentiation. Acting as a switch that induces the differentiation of naïve T cells into Th17 cells and inhibits their developme
Autor:
Donald E. Hricik, Brian Armstrong, Tarek Alhamad, Daniel C. Brennan, Jonathan S. Bromberg, Suphamai Bunnapradist, Sindhu Chandran, Robert. L. Fairchild, David P. Foley, Richard Formica, Ian W. Gibson, Karen Kesler, S. Joseph Kim, Roslyn B. Mannon, Madhav C. Menon, Kenneth A. Newell, Peter Nickerson, Jonah Odim, Emilio D. Poggio, Randall Sung, Ron Shapiro, Kathryn Tinckam, Flavio Vincenti, Peter S. Heeger
Publikováno v:
Journal of the American Society of Nephrology. 34:145-159
Autor:
Meixue Duan, Doan C. Nguyen, Chester J. Joyner, Celia L. Saney, Christopher M. Tipton, Joel Andrews, Sagar Lonial, Caroline Kim, Ian Hentenaar, Astrid Kosters, Eliver Ghosn, Annette Jackson, Stuart Knechtle, Stalinraja Maruthamuthu, Sindhu Chandran, Tom Martin, Raja Rajalingam, Flavio Vincenti, Cynthia Breeden, Ignacio Sanz, Greg Gibson, F. Eun-Hyung Lee
Publikováno v:
bioRxiv
Human bone marrow (BM) plasma cells are heterogeneous, ranging from newly arrived antibody-secreting cells (ASC) to long-lived plasma cells (LLPC). We provide single cell transcriptional resolution of 17,347 BM ASC from 5 healthy adults. Fifteen clus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bef429c2b90b99bda984fea60b901da
https://europepmc.org/articles/PMC9882341/
https://europepmc.org/articles/PMC9882341/
Autor:
Peter G. Stock, Sindhu Chandran
Publikováno v:
J Am Soc Nephrol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::473756d4c1129a79f3eaa23c509e1696
https://europepmc.org/articles/PMC8638393/
https://europepmc.org/articles/PMC8638393/