Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sinara M. V. de Almeida"'
Autor:
Gleyton Sousa, Maria C. F. de Almeida, Lucas L. Lócio, Vanda L. dos Santos, Daniel P. Bezerra, Valdenizia R. Silva, Sinara M. V. de Almeida, Alice Simon, Thiago da S. Honório, Lucio M. Cabral, Rosane N. Castro, Ricardo O. de Moura, Arthur E. Kümmerle
Publikováno v:
Pharmaceuticals, Vol 15, Iss 9, p 1098 (2022)
In this study, we report the synthesis of twenty new acridine–thiosemicarbazone derivatives and their antiproliferative activities. Mechanisms of action such as the inhibition of topoisomerase IIα and the interaction with DNA have been studied for
Externí odkaz:
https://doaj.org/article/b34c6a67d6bd4f02a04b3f2a8b81145f
Autor:
Sinara M. V. de Almeida, Ivan R. Pitta, Maria do Carmo A. de Lima, Francisco J. B. Mendonça Junior, Carlos A. de Simone
Publikováno v:
Acta Crystallographica Section E, Vol 69, Iss 2, Pp o224-o224 (2013)
In the title compound, C19H15NO4, the acridine system is essentially planar (r.m.s. deviation = 0.015 Å). The crystal packing exhibits π–π interactions between pairs of centrosymmetric molecules, one of them between the central heterocyclic ring
Externí odkaz:
https://doaj.org/article/4c8c1b2371af40e6b7ad953bf979db68
Autor:
Íris T T, Jacob, Fabiana O S, Gomes, Mirelly D S, de Miranda, Sinara M V, de Almeida, Iranildo J, da Cruz-Filho, Christina A, Peixoto, Teresinha G, da Silva, Diogo R M, Moreira, Cristiane M L, de Melo, Jamerson F, de Oliveira, Maria C A, de Lima
Publikováno v:
Pharmacological reports : PR. 73(3)
In this article, a series of 20 new thiosemicarbazone derivatives containing indole were synthesized and evaluated for their anti-inflammatory potential.The compounds were obtained through a synthetic route of only two steps, with yields that varied