Zobrazeno 1 - 10 of 16 pro vyhledávání: '"Sinan Caglayan"'
1
Microanalysis of eating behavior of three leptin deficient adults treated with leptin therapy
Autor: A. DiPaoli, Anthony J. Wagner, Metin Ozata, Donald A. Williamson, Cheryl Arnett, Julio Licinio, Sinan Caglayan, Heather Walden, Corby K. Martin, Eric Ravussin, Ma-Li Wong
Publikováno v: Appetite. 45:75-80
Leptin deficiency has been associated with extreme obesity and hyperphagia in rodents and humans. A rare genetic disorder in humans yields the absence of the hormone leptin, extreme obesity, and a ravenous appetite. Reports on these rare cases have i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5122c309db12eea5a84a4130d846085
https://doi.org/10.1016/j.appet.2005.01.002
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2
Effect of Leptin Replacement on Brain Structure in Genetically Leptin-Deficient Adults
Autor: Ma-Li Wong, Alex M. DePaoli, John A. Matochik, Bulent O. Yildiz, Sinan Caglayan, Edythe D. London, Julio Licinio, Metin Ozata
Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 90:2851-2854
The hormone leptin profoundly affects body weight and metabolism. Three human adults (two women, 35 and 40 yr old; one man, age 27) have been identified with a recessive mutation in the ob gene, which is homologous to the mutation in ob/ob mice, and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bd45dcc27a0cc7568eb117033e9bba1
https://doi.org/10.1210/jc.2004-1979
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3
Phenotypic effects of leptin replacement on morbid obesity, diabetes mellitus, hypogonadism, and behavior in leptin-deficient adults
Autor: Johannes D. Veldhuis, Sinan Caglayan, Bulent O. Yildiz, Ma-Li Wong, Julio Licinio, Alex M. DePaoli, Patricia B. de Miranda, Pinchas Cohen, Liyin Liang, Ronald M. Krauss, Shalender Bhasin, F. O'kirwan, Anthony J. Wagner, Samuel M. McCann, Robert Whitby, Metin Ozata
Publikováno v: Proceedings of the National Academy of Sciences. 101:4531-4536
Genetic mutations in the leptin pathway can be a cause of human obesity. It is still unknown whether leptin can be effective in the treatment of fully established morbid obesity and its endocrine and metabolic consequences in adults. To test the hypo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46a8896f42cc826b498dea24f381f9fe
https://doi.org/10.1073/pnas.0308767101
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4
Association of ACP1 genotypes and clinical parameters in patients with metabolic syndrome*
Autor: Gokhan Ozisik, Sidika Ayse Ozer, Cenk Aral, Zebra Atabey, Sinan Caglayan, Metin Ozata, Filiz Ozdemir Sertoglu, Mustafa Akkiprik
Publikováno v: Volume: 41, Issue: 3 533-541
Turkish Journal of Medical Sciences
Acid phosphatase locus 1 (ACP1) encodes a polymorphic enzyme and has potential implications for the development of metabolic syndrome (MS) by altering insulin sensitivity. The aim of this study was to determine whether a relationship exists between A
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93de423ac13ecb48873b6bc2831761ad
https://dergipark.org.tr/tr/pub/tbtkmedical/issue/12304/147264
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5
Event-related brain potentials in male hypogonadism
Autor: Okay Vural, Sinan Caglayan, Metin Ozata, C. Ozdemir, Zeki Odabasi, Zeynel Beyhan
Publikováno v: Journal of Endocrinological Investigation. 22:508-513
Several studies based on psychometric tests have determined an impairment of cognitive functions in patients with androgen deficiency. However, little is known about event-related potentials (ERPs) alterations in male hypogonadism. We investigated al
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3adaee1e5a142305b1056efd6e1ea463
https://doi.org/10.1007/bf03343601
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6
Magnetic resonance imaging of posterior pituitary for evaluation of the neurohypophyseal function in idiopathic and autosomal dominant neurohypophyseal diabetes insipidus
Autor: K. Kurtaran, M. Ozata, A Corakci, Zeynel Beyhan, C. Tayfun, I. Yetkin, Sinan Caglayan, M. A. Gündogan, A. Alemdaroglu
Publikováno v: European Radiology. 7:1098-1102
We investigated the role of MR imaging for evaluation of the functional status of the neurohypophyseal system in both idiopathic central diabetes insipidus (DI) and familial autosomal dominant neurohypophyseal DI. The patients and family with DI were
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::878937cad0170e5814f585876456fe4f
https://doi.org/10.1007/s003300050261
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7
Investigation of relationship of the mitochondrial DNA 16189 T > C polymorphism with metabolic syndrome and its associated clinical parameters in Turkish patients
Autor: Gokhan Ozisik, Ayşe Özer, Cenk Aral, Nuray Bekiroglu, Sinan Caglayan, Zehra Atabey, Mustafa Akkiprik
Publikováno v: Scopus-Elsevier
ResearcherID
OBJECTIVE: Mitochondrial DNA (mtDNA) polymorphisms have been implicated in the pathophysiology of human diseases. Among them, a T>C nucleotide transition on the 16189 nucleotide position of mtDNA has been studied in several metabolic diseases includi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::600513e720a83d63a234ce1734a5985c
https://hdl.handle.net/20.500.11776/6832
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8
Leptin replacement prevents weight loss-induced metabolic adaptation in congenital leptin-deficient patients
Autor: Eric Ravussin, Jose E. Galgani, Sinan Caglayan, Ma-Li Wong, Frank L. Greenway, Julio Licinio
Publikováno v: The Journal of clinical endocrinology and metabolism. 95(2)
Context: Leptin regulates energy homeostasis by suppressing food intake; however, its role in energy expenditure and fat oxidation remains uncertain in humans. Objective: The aim of the study was to assess 24-h energy metabolism before and after weig
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::633464f490c23c45496305e660d25d6e
https://pubmed.ncbi.nlm.nih.gov/20061423
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9
Mitochondrial DNA common deletion is not associated with thyroid, breast and colorectal tumors in Turkish patients
Autor: Cigdem Ataizi-Celikel, Mustafa Akkiprik, Huseyin Baloglu, Gokhan Ozisik, Sinan Caglayan, Ayşe Özer, Handan Kaya, Cenk Aral
Publikováno v: Genetics and Molecular Biology v.33 n.1 2010
Genetics and Molecular Biology
Sociedade Brasileira de Genética (SBG)
instacron:SBG
Genetics and Molecular Biology, Vol 33, Iss 1, Pp 1-4 (2010)
Genetics and Molecular Biology, Volume: 33, Issue: 1, Pages: 1-4, Published: 18 DEC 2009
Recently, efforts have been focused on mitochondrial DNA changes and their relation to human cancers. Among them, a 4977 bp deletion of mitochondrial DNA, named "common deletion", has been investigated in several types of tumors, with inconsistent re
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a75d8b02b48d8383fcf045f9d40af210
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572010000100001
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10
The effect of subclinical hypothyroidism on platelet parameters
Autor: Gokhan Ozisik, Isik Kaygusuz, Alev Akyol Erikçi, Ahmet Öztürk, Sinan Caglayan, Metin Ozata, Bülent Karagöz
Publikováno v: Hematology (Amsterdam, Netherlands). 14(2)
Hypothyroidism has a broad clinical spectrum. Today, physicians frequently encounter patients with very mild thyroid dysfunction instead of overt hypothyroidism. These patients have normal serum levels of thyroxine and triiodothyronine and only mildl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8cf15b4613516906aabcc39b6e1a8f8
https://pubmed.ncbi.nlm.nih.gov/19298725
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