Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sina Rupprecht"'
Autor:
Hans J. Lipps, Sina Rupprecht
Publikováno v:
Gene. 439:95-101
Non-viral episomal vectors are regarded as attractive alternatives to currently used virus-based vectors in gene therapy. In addition, they represent a minimal model system to study the epigenetic control of basic nuclear processes, such as transcrip
Publikováno v:
Biomolecular Concepts, Vol 1, Iss 1, Pp 17-30 (2010)
The discovery of autonomous replicating sequences (ARSs) inSaccharomyces cerevisiaein 1979 was considered a milestone in unraveling the regulation of replication in eukaryotic cells. However, shortly afterwards it became obvious that inSaccharomyces
Publikováno v:
Eukaryotic Cell. 4:1934-1941
Several models for specific excision of micronucleus-specific DNA sequences during macronuclear development in ciliates exist. While the template-guided recombination model suggests recombination events resulting in specific DNA excision and reorderi
Autor:
Verena Maier, Franziska Jönsson, Hans J. Lipps, Katrin Paeschke, Jan Postberg, Adrian G. Paschka, Sina Rupprecht, Matthias Möllenbeck
Publikováno v:
European Journal of Protistology. 39:449-454
The use of small double-stranded RNA to inhibit expression of genes has proven to be a powerful tool to analyze the biological function of genes in various eukaryotic organisms. We have established the RNAi technology in three genera of spirotrichous
Autor:
Davide Seruggia, Terese Magnusson, Hans J. Lipps, Sina Rupprecht, Claudia Hagedorn, Manfred Ogris, Ernst Wagner
Publikováno v:
Gene. 466(1-2)
An ideal vector to be used in gene therapy should allow long-term and regulated expression of the therapeutic sequence, but in many cases, it would be most desirable to remove all ectopic vector sequences from the cell once expression is no longer re
Autor:
Adrian G Paschka, Franziska Jönsson, Verena Maier, Matthias Möllenbeck, Katrin Paeschke, Jan Postberg, Sina Rupprecht, Hans J Lipps
Publikováno v:
European Journal of Protistology; Dec2003, Vol. 39 Issue 4, p449-454, 6p
Publikováno v:
BMC Cell Biology, Vol 8, Iss 1, p 33 (2007)
BMC Cell Biology
BMC Cell Biology
Background Basic functions of the eukaryotic nucleus, like transcription and replication, are regulated in a hierarchic fashion. It is assumed that epigenetic factors influence the efficiency and precision of these processes. In order to uncouple loc