Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Sina Neyazi"'
Autor:
Melanie Schoof, Shweta Godbole, Thomas K. Albert, Matthias Dottermusch, Carolin Walter, Annika Ballast, Nan Qin, Marlena Baca Olivera, Carolin Göbel, Sina Neyazi, Dörthe Holdhof, Catena Kresbach, Levke-Sophie Peter, Gefion Dorothea Epplen, Vanessa Thaden, Michael Spohn, Mirjam Blattner-Johnson, Franziska Modemann, Martin Mynarek, Stefan Rutkowski, Martin Sill, Julian Varghese, Ann-Kristin Afflerbach, Alicia Eckhardt, Daniel Münter, Archana Verma, Nina Struve, David T. W. Jones, Marc Remke, Julia E. Neumann, Kornelius Kerl, Ulrich Schüller
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Pediatric high-grade gliomas of the subclass MYCN (HGG-MYCN) are highly aggressive tumors frequently carrying MYCN amplifications, TP53 mutations, or both alterations. Due to their rarity, such tumors have only recently been identified as a
Externí odkaz:
https://doaj.org/article/09d9e0ef2e924a438dede74c6b3805ed
The tumor suppressor CREBBP and the oncogene MYCN cooperate to induce malignant brain tumors in mice
Autor:
Melanie Schoof, Gefion Dorothea Epplen, Carolin Walter, Annika Ballast, Dörthe Holdhof, Carolin Göbel, Sina Neyazi, Julian Varghese, Thomas Karl Albert, Kornelius Kerl, Ulrich Schüller
Publikováno v:
Oncogenesis, Vol 12, Iss 1, Pp 1-11 (2023)
Abstract The tumor suppressor and chromatin modifier cAMP response element-binding protein binding protein (CREBBP) and v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog (MYCN), a member of the MYC oncogene family, are critica
Externí odkaz:
https://doaj.org/article/b15682d4e3694e03b88707ff4e3a4985
Publikováno v:
Molecular and Cellular Pediatrics, Vol 9, Iss 1, Pp 1-9 (2022)
Abstract Long noncoding RNAs (lncRNAs) are increasingly emerging as regulators across human development and disease, and many have been described in the context of hematopoiesis and leukemogenesis. These studies have yielded new molecular insights in
Externí odkaz:
https://doaj.org/article/4eb31c7015f64ce889708255f1d55ef5
Autor:
Catena Kresbach, Matthias Dottermusch, Alicia Eckhardt, Inka Ristow, Petros Paplomatas, Lea Altendorf, Annika K Wefers, Michael Bockmayr, Sarra Belakhoua, Ivy Tran, Lara Pohl, Sina Neyazi, Helena Bode, Said Farschtschi, Lennart Well, Reinhard E Friedrich, David Reuss, Matija Snuderl, Christian Hagel, Victor-Felix Mautner, Ulrich Schüller
Publikováno v:
Neuro-Oncology.
Background Plexiform neurofibromas can transform into atypical neurofibromas (ANF) and then further progress to aggressive malignant peripheral nerve sheath tumors (MPNST). ANF have been described to harbor distinct histological features and frequent
Autor:
Sina Neyazi, Lea Altendorf, Dora Schwetje, Carolin Göbel, Melanie Schoof, Dörthe Holdhof, Ulrich Schüller
Publikováno v:
Brain pathology (Zurich, Switzerland)REFERENCES.
Publikováno v:
Brain pathology (Zurich, Switzerland). 32(4)
Ependymal neoplasms occur at all ages and encompass multiple tumor types and subtypes that develop in the supratentorial compartment, the posterior fossa, or the spinal cord. Clinically, ependymomas represent a very heterogeneous group of tumors from
Autor:
Schoof Melanie, Gefion Dorothea Epplen, Carolin Walter, Annika Ballast, Dörthe Holdhof, Carolin Göbel, Sina Neyazi, Thomas Albert, Kornelius Kerl, Ulrich Schüller
Publikováno v:
Neuro-Oncology. 24:i170-i171
CREBBP (cAMP response element-binding protein binding protein) and MYCN (v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog), two essential proteins in central nervous system development that are described to be genetically alt
Autor:
Sina Neyazi, Erika Yamazawa, Catena Kresbach, Genta Nagae, Alicia Eckhardt, Takayoshi Umeda, Lara Pohl, Kenji Tatsuno, Ceren Saygi, Taijun Hana, Malik Alawi, Phyo Kim, Mario M Dorostkar, Fumi Higuchi, Abigail K Suwala, Toshihiro Takami, Annika Wefers, Yuta Nakanishi, Leonille Schweizer, Keisuke Takai, Lara Engertsberger, Takashi Komori, Theresa Mohme, Hirokazu Takami, Martin Mynarek, Masashi Nomura, Karin Lamszus, Akitake Mukasa, Lan Kluwe, Shunsaku Takayanagi, Andreas von Deimling, Kazuhiko Ishii, Martin Benesch, Hideaki Imai, Matija Snuderl, Stephan Frank, Koichi Ichimura, Christian Hagel, Viktor F Mautner, Stefan Rutkowski, Shota Tanaka, Hiroyuki Aburatani, Saito Nobuhito, Ulrich Schüller
Publikováno v:
Neuro-Oncology. 24:i44-i45
Ependymomas encompass multiple, clinically relevant tumor types based on localization, genetic alterations, and epigenetic and transcriptomic profiles. Tumors belonging to the methylation class of spinal ependymoma (SP-EPN) represent the most common
Autor:
Melanie Schoof, Michael Spohn, Mario Dorostkar, Sina Neyazi, Michael Bockmayr, Fredrik Swartling, Daisuke Kawauchi, Richard Gilbertson, Jessica Taylor, Yanxin Pei, Rainer Glass, Jiying Cheng, Natalia Moreno Galarza, Juergen Hench, Jochen Herms, Philipp Jurmeister, Leonille Schweizer, David Capper, Patrick Harter, Christian Thomas, Martin Hasselblatt, Mirjam Blattner-Johnson, David Jones, Stephan Frank, Kornelius Kerl, Ulrich Schüller
Publikováno v:
Neuro-Oncology. 24:i158-i159
The classification of human brain tumors by global DNA methylation profiling has become an essential part of modern integrated neuropathological diagnostics. It has proven to reliably identify known and novel brain tumor (sub-)types that are biologic
Autor:
Christian Mawrin, Ralf Koch, Natalie Waldt, I. Erol Sandalcioglu, Werner E. K. Braunsdorf, Jan‐Peter Warnke, Felix Goehre, Hans‐Jürgen Meisel, Christian Ewald, Sina Neyazi, Ulrich Schüller, Elmar Kirches
Publikováno v:
Brain pathology (Zurich, Switzerland). 32(2)
Meningiomas are the most frequent primary intracranial tumors. The considerable variety of histological subtypes has been expanded by the definition of molecular alterations, which can improve both diagnostic accuracy and determination of individual