Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sina M. Hopff"'
Autor:
Tim J. Hartung, Thomas Bahmer, Irina Chaplinskaya-Sobol, Jürgen Deckert, Matthias Endres, Katrin Franzpötter, Johanna Geritz, Karl G. Haeusler, Grit Hein, Peter U. Heuschmann, Sina M. Hopff, Anna Horn, Thomas Keil, Michael Krawczak, Lilian Krist, Wolfgang Lieb, Corina Maetzler, Felipe A. Montellano, Caroline Morbach, Christian Neumann, Carolin Nürnberger, Anne-Kathrin Russ, Lena Schmidbauer, Sein Schmidt, Stefan Schreiber, Flo Steigerwald, Stefan Störk, Thomas Zoller, Walter Maetzler, Carsten Finke
Publikováno v:
EClinicalMedicine, Vol 69, Iss , Pp 102456- (2024)
Summary: Background: Despite the high prevalence and major disability associated with fatigue and cognitive deficits after SARS-CoV-2 infection, little is known about long-term trajectories of these sequelae. We aimed to assess long-term trajectories
Externí odkaz:
https://doaj.org/article/989245ea2ce048df933432e9377840c9
Autor:
Katharina Tilch, Sina M. Hopff, Katharina Appel, Monika Kraus, Bettina Lorenz-Depiereux, Lisa Pilgram, Gabi Anton, Sarah Berger, Ramsia Geisler, Kirsten Haas, Thomas Illig, Dagmar Krefting, Roberto Lorbeer, Lazar Mitrov, Maximilian Muenchhoff, Matthias Nauck, Christina Pley, Jens-Peter Reese, Siegbert Rieg, Margarete Scherer, Melanie Stecher, Christoph Stellbrink, Heike Valentin, Christof Winter, Martin Witzenrath, J. Janne Vehreschild
Publikováno v:
BMC Medical Ethics, Vol 24, Iss 1, Pp 1-16 (2023)
Abstract With the outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), global researchers were confronted with major challenges. The German National Pandemic Cohort Network (NAPKON) was launched in fall 2020 to effectively levera
Externí odkaz:
https://doaj.org/article/4edf526535364b018d9c6b0891af0e66
Statistical biases due to anonymization evaluated in an open clinical dataset from COVID-19 patients
Autor:
Carolin E. M. Koll, Sina M. Hopff, Thierry Meurers, Chin Huang Lee, Mirjam Kohls, Christoph Stellbrink, Charlotte Thibeault, Lennart Reinke, Sarah Steinbrecher, Stefan Schreiber, Lazar Mitrov, Sandra Frank, Olga Miljukov, Johanna Erber, Johannes C. Hellmuth, Jens-Peter Reese, Fridolin Steinbeis, Thomas Bahmer, Marina Hagen, Patrick Meybohm, Stefan Hansch, István Vadász, Lilian Krist, Steffi Jiru-Hillmann, Fabian Prasser, Jörg Janne Vehreschild, NAPKON Study Group
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-15 (2022)
Abstract Anonymization has the potential to foster the sharing of medical data. State-of-the-art methods use mathematical models to modify data to reduce privacy risks. However, the degree of protection must be balanced against the impact on statisti
Externí odkaz:
https://doaj.org/article/28a3080393434801b72639368e05f863
Autor:
Andreas Stein, Persefoni Hilken née Thomopoulou, Corazon Frias, Sina M. Hopff, Paloma Varela, Nicola Wilke, Arul Mariappan, Jörg-Martin Neudörfl, Alexey Yu Fedorov, Jay Gopalakrishnan, Benoît Gigant, Aram Prokop, Hans-Günther Schmalz
Publikováno v:
ACS Omega, Vol 7, Iss 3, Pp 2591-2603 (2022)
Externí odkaz:
https://doaj.org/article/b9771bb895fa4ea4b4685ea98a2825e6
Autor:
Dagmar Krefting, Gabi Anton, Irina Chaplinskaya-Sobol, Sabine Hanss, Wolfgang Hoffmann, Sina M. Hopff, Monika Kraus, Roberto Lorbeer, Bettina Lorenz-Depiereux, Thomas Illig, Christian Schäfer, Jens Schaller, Dana Stahl, Heike Valentin, Peter Heuschmann, Janne Vehreschild
Publikováno v:
Caring is Sharing – Exploiting the Value in Data for Health and Innovation ISBN: 9781643683881
The COVID-19 pandemic has urged the need to set up, conduct and analyze high-quality epidemiological studies within a very short time-scale to provide timely evidence on influential factors on the pandemic, e.g. COVID-19 severity and disease course.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa2baf75fc2ac82ce218702a5ad25b3f
https://doi.org/10.3233/shti230071
https://doi.org/10.3233/shti230071
Autor:
Sebastian M. Wingen-Heimann, Kerrie Davies, Virginie F. Viprey, Georgina Davis, Mark H. Wilcox, Maria J.G.T. Vehreschild, Lise Lurienne, Pierre-Alain Bandinelli, Oliver A. Cornely, Tuba Vilken, Sina M. Hopff, Jörg Janne Vehreschild, null Academic Partners, Marc Bonten, Kerrie A. Davies, Ed Kuijper, Maja Rupnik, Sebastian Wingen-Heimann, Evelina Tacconelli, Nicola Petrosillo, null EFPIA Partners, null Pfizer Ltd, null GlaxoSmithKline, null bioMérieux, Sanofi Pasteur, null Da Volterra, null The Management Board of COMBACTE-CDI, Philippe Cleuziat, Chris Webber
Publikováno v:
Clinical microbiology and infection
Objectives: Clostridioides difficile infection (CDI) is one of the leading nosocomial infections worldwide, resulting in a significantly increasing burden on the healthcare systems. However, Pan-European data about cost and resource utilization of CD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1859db01513111432eb169cbb121eae
https://hdl.handle.net/10067/1974680151162165141
https://hdl.handle.net/10067/1974680151162165141
Autor:
Katharina S Appel, Daniel Maier, Sina M Hopff, Lazar Mitrov, Melanie Stecher, Margarete Scherer, Ramsia Geisler, Marina Hagen, Kirsten Haas, Jens-Peter Reese, Steffi Jiru-Hillmann, Olga Miljukov, Carolin E M Jakob, Susana M Nunes de Miranda, Patrick Meybohm, Sabine Hanß, Johanna Erber, Christof Winter, Johannes J Tebbe, Christoph Stellbrink, Yascha Khodamoradi, Julia Schmidt, Frank Hanses, Christian Scheer, Sabine Blaschke, Siri Göpel, Stefan Kluge, Oliver Witzke, Christoph Römmele, Marcin Krawczyk, Andreas Teufel, Jonas Schmid, Daniel Pape, Christian Schütte, Kristin Tausche, Milena Milovanovic, Natalie Krug, Phil-Robin Tepasse, Marlo Verket, Axel Hamprecht, Selcuk Tasci, Martin Hower, Björn-Erik O Jensen, Martin F Sprinzl, Tim Zimmermann, Jörg J Vehreschild
Publikováno v:
Open Forum Infectious Diseases. 9
Background Numerous predictive clinical scores with varying discriminatory performance have been developed in the context of the current coronavirus disease 2019 (COVID-19) pandemic. To support clinical application, we test the transferability of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49ab3ed0863642e5ccedb33a46bcd105
https://doi.org/10.1093/ofid/ofac492.1513
https://doi.org/10.1093/ofid/ofac492.1513
Autor:
Nicola L Wilke, Qifang Wang, Nathalie Wilke, Marie Ahrweiler, Sina M. Hopff, Albrecht Berkessel, Aram Prokop, Corazon Frias
Publikováno v:
Journal of Cancer Research and Clinical Oncology
Purpose Since the discovery of the well-known cis-platin, transition metal complexes are highly recognized as cytostatic agents. However, toxic side effects of the metal ions present in the complexes may pose significant problems for their future dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45e3a6c6302d7df4c6f4674c0d75706b
https://doi.org/10.1007/s00432-021-03679-3
https://doi.org/10.1007/s00432-021-03679-3
Publikováno v:
Bioorganic chemistry. 104
A very small number of cobalt complexes is examined in oncology research. In this work, we investigate the cobalt (III) salen complex MBR-60 that turns out to be a promising anticancer drug. It induces apoptosis in Nalm6 leukemia and BJAB lymphoma ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90cf9c587576759ec4c986291bbd71f6
https://pubmed.ncbi.nlm.nih.gov/32947134
https://pubmed.ncbi.nlm.nih.gov/32947134
Publikováno v:
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. 34(2)
We investigated the aluminium-salen complex MBR-8 as a potential anti-cancer agent. To see apoptotic effects induced by MBR-8, alone and in combination with common cytostatic drugs, DNA-fragmentations were studied using the flow cytometric analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d478add3fea28638884f7fd73f4dd2e
https://pubmed.ncbi.nlm.nih.gov/33560473
https://pubmed.ncbi.nlm.nih.gov/33560473