Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sina Kreth"'
Autor:
Hamed Alborzinia, Andrés F. Flórez, Sina Kreth, Lena M. Brückner, Umut Yildiz, Moritz Gartlgruber, Dorett I. Odoni, Gernot Poschet, Karolina Garbowicz, Chunxuan Shao, Corinna Klein, Jasmin Meier, Petra Zeisberger, Michal Nadler-Holly, Matthias Ziehm, Franziska Paul, Jürgen Burhenne, Emma Bell, Marjan Shaikhkarami, Roberto Würth, Sabine A. Stainczyk, Elisa M. Wecht, Jochen Kreth, Michael Büttner, Naveed Ishaque, Matthias Schlesner, Barbara Nicke, Carlo Stresemann, María Llamazares-Prada, Jan H. Reiling, Matthias Fischer, Ido Amit, Matthias Selbach, Carl Herrmann, Stefan Wölfl, Kai-Oliver Henrich, Thomas Höfer, Andreas Trumpp, Frank Westermann
Publikováno v:
Nature Cancer. 3:471-485
Aberrant expression of MYC transcription factor family members predicts poor clinical outcome in many human cancers. Oncogenic MYC profoundly alters metabolism and mediates an antioxidant response to maintain redox balance. Here we show that MYCN ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c7536a176e1107cc031d9f0b5816ea5
https://doi.org/10.1038/s43018-022-00355-4
https://doi.org/10.1038/s43018-022-00355-4
Autor:
Johan van Nes, Moritz Gartlgruber, Rogier Versteeg, Andres Quintero, Frank Westermann, Elena A. Afanasyeva, David T.W. Jones, Elisa M. Wecht, Paul Saary, Ashwini Kumar Sharma, Sina Kreth, Johanna Meder, Daria Doncevic, Carl Herrmann, Umut H. Toprak, Thomas G. P. Grunewald, Stefan M. Pfister, Young-Gyu Park, Jan Koster, Naveed Ishaque, Selina Jansky, Daniel Dreidax, Kai-Oliver Henrich
Publikováno v:
Nature Cancer, 2(1), 114-128. Nature Research
Half of the children diagnosed with neuroblastoma (NB) have high-risk disease, disproportionately contributing to overall childhood cancer-related deaths. In addition to recurrent gene mutations, there is increasing evidence supporting the role of ep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::690e84dc9638842aa81089f50fe1b78f
http://www.scopus.com/inward/record.url?scp=85097226348&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85097226348&partnerID=8YFLogxK
Autor:
Olaf Witt, Sina Oppermann, Yannick Berker, Heike Peterziel, Sina Kreth, Matthias Schlesner, Ina Oehme, Dina ElHarouni, Vilja Pietiäinen, Laura Turunen, Apurva Gopisetty, Natalie Jäger, Sabine A. Stainczyk
Publikováno v:
Pharmacological research. 175
High throughput screening methods, measuring the sensitivity and resistance of tumor cells to drug treatments have been rapidly evolving. Not only do these screens allow correlating response profiles to tumor genomic features for developing novel pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9c010be5e24e3c3a6b719fca4c33915
https://pubmed.ncbi.nlm.nih.gov/34848323
https://pubmed.ncbi.nlm.nih.gov/34848323
Autor:
Martin Lange, Erik Schulz, Mario Huerta, Mona Blatter, Ali Nowrouzi, Bernhard Kuster, Ulrike Uhrig, Karin Laaber, Axel Benner, Hanno Glimm, Claudia R. Ball, Sina Kreth, Dominik Mumberg, Kerstin Putzker, Friederike Herbst, Joerg Weiske, Hannes Hahne, Sarah Johannes, Gerhard Siemeister, Frank Westermann, Andrea Haegebarth, Martina K. Zowada, Gabriele Stoehr, Simon Holton, Paula L Codo, Joe Lewis, Sebastian M. Dieter, Ulrike Scheib, Lena-Marit Toepper, Sylvia Martin, Christine Siegl, Anna L. Ostermann-Parucha
Summary Novel treatment options for metastatic colorectal cancer (CRC) are urgently needed to improve patient outcome. Here, we screen a library of non-characterized small molecules against a heterogeneous collection of patient-derived CRC spheroids.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a410f992a87b35fec1505c6f97a79632
https://mediatum.ub.tum.de/doc/1652086/document.pdf
https://mediatum.ub.tum.de/doc/1652086/document.pdf
Autor:
Charlotte Gatzweiler, Johannes Ridinger, Sonja Herter, Xenia F. Gerloff, Dina ElHarouni, Yannick Berker, Roland Imle, Lukas Schmitt, Sina Kreth, Sabine Stainczyk, Simay Ayhan, Sara Najafi, Damir Krunic, Karen Frese, Benjamin Meder, David Reuss, Petra Fiesel, Kathrin Schramm, Mirjam Blattner-Johnson, David T. W. Jones, Ana Banito, Frank Westermann, Sina Oppermann, Till Milde, Heike Peterziel, Olaf Witt, Ina Oehme
Publikováno v:
Cancers; Volume 14; Issue 3; Pages: 849
Cancers, Vol 14, Iss 849, p 849 (2022)
Cancers, Vol 14, Iss 849, p 849 (2022)
The survival rate among children with relapsed tumors remains poor, due to tumor heterogeneity, lack of directly actionable tumor drivers and multidrug resistance. Novel personalized medicine approaches tailored to each tumor are urgently needed to i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff12b95334a3e985de18262d9f0c2076
https://doi.org/10.3390/cancers14030849
https://doi.org/10.3390/cancers14030849
Autor:
Olaf Witt, Xenia F. Gerloff, Sina Kreth, David T.W. Jones, Sara Najafi, Karen S. Frese, Michael W. Müller, Frank Westermann, Till Milde, Sabine A. Stainczyk, Johannes Ridinger, Charlotte Gatzweiler, Jochen Baßler, Heike Peterziel, Lisa Rösch, Benjamin Meder, Ina Oehme
Publikováno v:
Cancers; Volume 13; Issue 17; Pages: 4476
Cancers, Vol 13, Iss 4476, p 4476 (2021)
Cancers
Cancers, Vol 13, Iss 4476, p 4476 (2021)
Cancers
Simple Summary Preclinical analyses identified APR-246 as a potent treatment option for neuroblastoma. However, a specific mode of action, sufficient biomarkers and promising combination partners are still missing. Here, we analyze the susceptibiliti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb993d033a6dae515d292ece04a9bfda
https://doi.org/10.3390/cancers13174476
https://doi.org/10.3390/cancers13174476
Autor:
Müller, Michael1,2,3 (AUTHOR) mic.mueller@kitz-heidelberg.de, Rösch, Lisa1,2,4 (AUTHOR) l.roesch@kitz-heidelberg.de, Najafi, Sara1,2,5 (AUTHOR) s.najafi@kitz-heidelberg.de, Gatzweiler, Charlotte1,2,3 (AUTHOR) charlotte.gatzweiler@kitz-heidelberg.de, Ridinger, Johannes1,2 (AUTHOR) j.ridinger@kitz-heidelberg.de, Gerloff, Xenia F.1,2,5 (AUTHOR) xenia.gerloff@dkfz-heidelberg.de, Jones, David T. W.1,6 (AUTHOR) david.jones@kitz-heidelberg.de, Baßler, Jochen7 (AUTHOR) jochen.bassler@bzh.uni-heidelberg.de, Kreth, Sina1,8 (AUTHOR) s.kreth@kitz-heidelberg.de, Stainczyk, Sabine1,8 (AUTHOR) s.stainczyk@kitz-heidelberg.de, Frese, Karen9 (AUTHOR) karen.frese@med.uni-heidelberg.de, Meder, Benjamin9,10 (AUTHOR) Benjamin.Meder@med.uni-heidelberg.de, Westermann, Frank1,8 (AUTHOR) f.westermann@kitz-heidelberg.de, Milde, Till1,2,5 (AUTHOR) t.milde@kitz-heidelberg.de, Peterziel, Heike1,2 (AUTHOR) h.peterziel@kitz-heidelberg.de, Witt, Olaf1,2,5 (AUTHOR) o.witt@kitz-heidelberg.de, Oehme, Ina1,2 (AUTHOR) i.oehme@kitz-heidelberg.de
Publikováno v:
Cancers. Sep2021, Vol. 13 Issue 17, p4476. 1p.