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pro vyhledávání: '"Sina Bader"'
Publikováno v:
Free Radical Biology and Medicine. 168:44-54
The efficacy of radiotherapy depends not only on DNA damage but also on ROS production, both induced by ionizing radiation. Massive ROS production can induce cell death or activate protective pathways such as Keap1/Nrf2 pathway, which regulates intra
Autor:
Arnau Ulsamer, Adrián Martínez-Limón, Sina Bader, Sara Rodríguez-Acebes, Raimundo Freire, Juan Méndez, Eulàlia de Nadal, Francesc Posas
Stress-activated protein kinases (SAPKs) enhance survival in response to environmental changes. In yeast, the Hog1 SAPK and Mrc1, a protein required for DNA replication, define a safeguard mechanism that allows eukaryotic cells to prevent genomic ins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7934b2cbbd7313e9d091facd755cce3
http://hdl.handle.net/10230/54827
http://hdl.handle.net/10230/54827
Autor:
Sina Bader, Verena Jendrossek, Teona Ontikatze, Violetta Ritter, Julia Wilmers, Justine Rudner
Publikováno v:
Free radical biologymedicine. 174
Tumor hypoxia is a major biological factor that drives resistance to chemotherapy and radiotherapy. We previously demonstrated that the pro-oxidative drug dihydroartemisinin (DHA) efficiently targeted normoxic and hypoxic cancer cells. Although well