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Synthesis and molecular docking studies of new aryl imeglimin derivatives as a potent antidiabetic agent in a diabetic zebrafish model

Autor: Aylin Khodakhah, Hassan Mohammadi, Sina Abdoli, Issa Zarei, Mahdie Palimi, Zeinab Ekhtiari, Meysam Talebi, Mahmood Biglar, Mohammad Reza Khorramizadeh, Massoud Amanlou

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)

Abstract Diabetes mellitus (DM) is a persistent, progressive, and multifaceted disease characterized by elevated blood glucose levels. Type 2 diabetes mellitus is associated with a relative deficit in insulin mainly due to beta cell dysfunction and p

Externí odkaz: https://doaj.org/article/4b881e6de9774691995f862f7e9e61f2

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Preclinical studies of chimeric antigen receptor-modified natural killer cells in cancer immunotherapy: a review

Autor: Zahra Habibi, Sina Abdoli, Nima Rezaei, Narges Hosseini, Mina Hosseini

Publikováno v: Expert Opinion on Biological Therapy. 22:349-366

Introduction As one of the most efficacious methods of cancer immunotherapy, chimeric antigen receptor-modified immune cells have recently drawn enormous attention. After the great success achieved with CAR-T-cells in cancer treatment both in preclin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbb153004f78f3a46a9f17c960a9e2aa
https://doi.org/10.1080/14712598.2021.1983539

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