Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Sin-Yee Fung"'
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Background SARS-CoV-2 is the causative agent of COVID-19. Overproduction and release of proinflammatory cytokines are the underlying cause of severe COVID-19. Treatment of this condition with JAK inhibitors is a double-edged sword, which mig
Externí odkaz:
https://doaj.org/article/4520870a0afe4980afa65cf0dcaf00e6
Publikováno v:
Cell & Bioscience, Vol 11, Iss 1, Pp 1-6 (2021)
Abstract In February 2020, we highlighted the top nine important research questions on SARS-CoV-2 and COVID-19 concerning virus transmission, asymptomatic and presymptomatic virus shedding, diagnosis, treatment, vaccine development, origin of virus a
Externí odkaz:
https://doaj.org/article/788a51cc7f3c446da1f20d87650dfcbf
Publikováno v:
Cell & Bioscience, Vol 10, Iss 1, Pp 1-5 (2020)
Abstract Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an ongoing global health emergency. Here we highlight nine most important research questions concerning virus transmission, asympto
Externí odkaz:
https://doaj.org/article/b6975efce1914b1792c709c0f25510f5
Publikováno v:
Emerging Microbes and Infections, Vol 9, Iss 1, Pp 558-570 (2020)
ABSTRACTWorld Health Organization has declared the ongoing outbreak of coronavirus disease 2019 (COVID-19) a Public Health Emergency of International Concern. The virus was named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by the Int
Externí odkaz:
https://doaj.org/article/0dfda238a33d4012bbb4fd8bb3bc3d45
Autor:
Pak‐Hin Hinson Cheung, Zi‐Wei Ye, Wai‐Yin Lui, Chon Phin Ong, Pearl Chan, Tak‐Wang Terence Lee, Tze‐Tung Tang, Tin‐Long Yuen, Sin‐Yee Fung, Yun Cheng, Ching‐Ping Chan, Chi‐Ping Chan, Dong‐Yan Jin
Publikováno v:
Journal of Medical Virology. 94:6078-6090
Single-cycle infectious virus can elicit close-to-natural immune response and memory. One approach to generate single-cycle severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is through deletion of structural genes such as spike (S) and nuc
Publikováno v:
International Journal of Biological Sciences
Suppression of type I interferon (IFN) response is one pathological outcome of the infection of highly pathogenic human coronaviruses. To effect this, severe acute respiratory syndrome coronavirus (SARS-CoV) and SARS-CoV-2 encode multiple IFN antagon
Autor:
Kit-San Yuen, Sin Yee Fung, Chi-Ping Chan, Pak Yin Lui, Xuyang Zheng, Zongwei Cai, Lok Yin Roy Wong, Kwok-Yung Yuen, Dong-Yan Jin, Kam Leung Siu, Man Lung Yeung, Lin Zhu, Shuofeng Yuan, Zi-Wei Ye, Patrick C. Y. Woo
Publikováno v:
J Immunol
Middle East respiratory syndrome coronavirus (MERS-CoV) is a highly pathogenic human coronavirus causing severe disease and mortality. MERS-CoV infection failed to elicit robust IFN response, suggesting that the virus might have evolved strategies to
Publikováno v:
Cell & Bioscience
Cell & bioscience, 10:40
Cell & Bioscience, Vol 10, Iss 1, Pp 1-5 (2020)
Cell & bioscience, 10:40
Cell & Bioscience, Vol 10, Iss 1, Pp 1-5 (2020)
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an ongoing global health emergency. Here we highlight nine most important research questions concerning virus transmission, asymptomatic and
Publikováno v:
International Journal of Biological Sciences
Mutation and adaptation have driven the co-evolution of coronaviruses (CoVs) and their hosts, including human beings, for thousands of years. Before 2003, two human CoVs (HCoVs) were known to cause mild illness, such as common cold. The outbreaks of