Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Sin-Lun Li"'
Publikováno v:
Life Sciences. 92:719-726
The aim of this study is to investigate the protective effects of cystamine on lupus-associated cardiac hypertrophy.Balb/c and lupus-prone NZB/W-F1 mice were individually randomized into sham group (saline, n=16) and cystamine group (n=16). Mice rece
Autor:
Wen-Xian Lai, Sin-Lun Li, Shao-Hsuan Kao, Jau-Song Yu, Bor-Show Tzang, Tsai-Ching Hsu, Jeng-Ting Chen
Publikováno v:
Journal of Cellular Biochemistry. 110:660-670
Increased macrophage vulnerability is associated with progression of systemic lupus erythematosus. Our previous studies have shown that cystamine, an inhibitor of transglutaminase 2 (TG2), alleviated the apoptosis of hepatocyte and brain cell in lupu
Publikováno v:
Food Chemistry. 119:62-68
A hypercholesterolemic diet has been associated with the hepatic abnormalities and the pathological processes of systemic lupus erythematosus (SLE). To investigate the effects of taurine on the hepatic abnormality in SLE, NZB/W F1 mice were used as a
Autor:
Joung-Liang Lan, Bor-Show Tzang, Sin Lun Li, Shao-Hsuan Kao, Chih Yang Huang, Tsai-Ching Hsu, Yin Chang Liu
Publikováno v:
The Chinese Journal of Physiology. 53:11-18
Antibodies against the proliferating cell nuclear antigen (PCNA) was first discovered in the sera of systemic lupus erythematosus (SLE) patients. However, the reactivity and specificity of anti-PCNA autoantibodies are still unclear. To investigate th
Publikováno v:
European Journal of Pharmacology. 607:102-106
Evidence have indicated the impairment of central nervous system (CNS) and neuropsychiatric disorder in patients with systemic lupus erythematosus (SLE). However, little is known to improve the brain abnormality in SLE. To investigate the effect of c
Autor:
Shao-Hsuan Kao, Sin-Lun Li, Tzy-Yen Chen, Bor-Show Tzang, Tsai-Ching Hsu, Cheng-Yi Kuo, Szu-Yi Chiang
Publikováno v:
Journal of Cellular and Molecular Medicine
Cystamine, a disulphide metabolite, has been demonstrated to ameliorate various lupus-associated tissue damages by animal models. However, effects of cystamine on apoptosis of cardiac tissue, a main cardiac damage attributing to lupus, are less obvio