Zobrazeno 1 - 10
of 530
pro vyhledávání: '"Sin‐Ho Jung"'
Publikováno v:
Biomedicines, Vol 12, Iss 10, p 2185 (2024)
Objectives: The design of cancer clinical trials incorporating biomarkers depends on various factors, including the trial phase, the type of biomarker and whether its role has been validated. This article aims to present a method for designing and an
Externí odkaz:
https://doaj.org/article/ade355a974ff42b389ff61cf2af0ff7d
Autor:
Sin-Ho Jung
Publikováno v:
Diagnostics, Vol 14, Iss 16, p 1813 (2024)
Diagnostic biomarkers are key components of diagnostics. In this paper, we consider diagnostic biomarkers taking continuous values that are associated with a dichotomous disease status, called malignant or benign. The performance of such a biomarker
Externí odkaz:
https://doaj.org/article/767308fc889d4f0a87d94a591255ecf7
Autor:
Ashley L Artese, Hilary M Winthrop, Lauren Bohannon, Meagan V Lew, Ernaya Johnson, Grace MacDonald, Yi Ren, Amy M Pastva, Katherine S Hall, Paul E Wischmeyer, David Macleod, Jeroen Molinger, Stratton Barth, Sin-Ho Jung, Harvey Jay Cohen, David B Bartlett, Anthony D Sung
Publikováno v:
PLoS ONE, Vol 18, Iss 11, p e0293171 (2023)
IntroductionAlthough allogeneic hematopoietic stem cell transplantation (HCT) can be a curative therapy for hematologic disorders, it is associated with treatment-related complications and losses in cardiorespiratory fitness and physical function. Hi
Externí odkaz:
https://doaj.org/article/a88573c5a70e4fb387d6402131b484f5
Autor:
Jihad Abdelgadir, Aden P Haskell-Mendoza, Amanda R Magno, Alexander D Suarez, Prince Antwi, Alankrita Raghavan, Patricia Nelson, Lexie Zidanyue Yang, Sin-Ho Jung, Ali R Zomorodi
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0285982 (2023)
ObjectiveDespite advances in the nonsurgical management of cerebrovascular atherosclerotic steno-occlusive disease, approximately 15-20% of patients remain at high risk for recurrent ischemia. The benefit of revascularization with flow augmentation b
Externí odkaz:
https://doaj.org/article/835102d1977c45d9ad1cb3cb57293c67
Publikováno v:
Mathematics, Vol 11, Iss 17, p 3738 (2023)
Machine learning methods have been a standard approach to select features that are associated with an outcome and to build a prediction model when the number of candidate features is large. LASSO is one of the most popular approaches to this end. The
Externí odkaz:
https://doaj.org/article/f6df4ebb2c3348b29bde0eccf43f9141
Autor:
Vishal Venkatraman, Elayna P Kirsch, Emily Luo, Sameer Kunte, Madison Ponder, Ziad F Gellad, Beiyu Liu, Hui-Jie Lee, Sin-Ho Jung, Michael M Haglund, Shivanand P Lad
Publikováno v:
JMIR Perioperative Medicine, Vol 5, Iss 1, p e38690 (2022)
BackgroundDigital health solutions have been shown to enhance outcomes for individuals with chronic medical illnesses, but few have been validated for surgical patients. The digital health platform ManageMySurgery (MMS) has been validated for spine s
Externí odkaz:
https://doaj.org/article/886156b0133643d18576e2925ca9847d
Autor:
Matthias Gromeier, Darell D Bigner, Smita K Nair, David Boczkowski, Michael C Brown, Karenia Landa, Sin-Ho Jung, Georgia M Beasley, Norma E Farrow, Maria Angelica Selim, Rami N Al-Rohil, Aaron D Therien, Junheng Gao, Eda K Holl
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 9 (2022)
Background We previously reported results from a phase 1 study testing intratumoral recombinant poliovirus, lerapolturev, in 12 melanoma patients. All 12 patients received anti-PD-1 systemic therapy before lerapolturev, and 11 of these 12 patients al
Externí odkaz:
https://doaj.org/article/04605eb95ab14089a2829c1d83ca4646
Autor:
Jillian C Thompson, Yi Ren, Kristi Romero, Meagan Lew, Amy T Bush, Julia A Messina, Sin-Ho Jung, Sharareh Siamakpour-Reihani, Julie Miller, Robert R Jenq, Jonathan U Peled, Marcel R M van den Brink, Nelson J Chao, Mark G Shrime, Anthony D Sung
Publikováno v:
PLoS ONE, Vol 17, Iss 5, p e0267974 (2022)
IntroductionIn order to study the role of the microbiome in hematopoietic stem cell transplantation (HCT), researchers collect stool samples from patients at various time points throughout HCT. However, stool collection requires active subject partic
Externí odkaz:
https://doaj.org/article/32f8e78d83b348058c16f65921bcc7e9
Autor:
Sin-Ho Jung, Helen Tang, Lauren Bohannon, Meagan Lew, David Jensen, Aaron Zhao, Anthony D Sung, Paul E Wischmeyer
Publikováno v:
BMJ Open, Vol 11, Iss 5 (2021)
Introduction The COVID-19 pandemic has proven to be an unprecedented challenge to worldwide health, and strategies to mitigate the spread and severity of COVID-19 infection are urgently needed. Emerging evidence suggests that the composition of the g
Externí odkaz:
https://doaj.org/article/3c8fdb2367494c63bb963c69acc05935
Autor:
Matthias Gromeier, Darell D Bigner, Smita K Nair, Karenia Landa, Sin-Ho Jung, Georgia M Beasley, Norma E Farrow, Maria Angelica Selim, Carol Ann Wiggs, Andrea True Kelly, April KS Salama
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 4 (2021)
Background While programmed cell death protein 1 (PD-1) and programmed death-ligand 1 (PD-L1) antagonists have improved the prognosis for many patients with melanoma, around 60% fail therapy. PVSRIPO is a non-neurovirulent rhinovirus:poliovirus chime
Externí odkaz:
https://doaj.org/article/e28cb6ceb21645b987a84e695f9c4187