Preclinical activity of CPI-0610, a novel small-molecule bromodomain and extra-terminal protein inhibitor in the therapy of multiple myeloma.

Autor: Siu KT; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA., Ramachandran J; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA., Yee AJ; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA., Eda H; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA., Santo L; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA., Panaroni C; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA., Mertz JA; Constellation Pharmaceuticals, Inc., Cambridge, MA, USA., Sims Iii RJ; Constellation Pharmaceuticals, Inc., Cambridge, MA, USA., Cooper MR; Constellation Pharmaceuticals, Inc., Cambridge, MA, USA., Raje N; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA.

Publikováno v: Leukemia [Leukemia] 2017 Aug; Vol. 31 (8), pp. 1760-1769. Date of Electronic Publication: 2016 Nov 28.