Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Simranjit S. Pattar"'
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 6 (2019)
The epicardial surface of the heart is readily accessible during cardiac surgery and presents an opportunity for therapeutic intervention for cardiac repair and regeneration. As an important anatomic niche for endogenous mechanisms of repair, targeti
Externí odkaz:
https://doaj.org/article/58798f4c7a6644fc98a5f9ae3fa934e2
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Heart failure is a progressive deterioration of cardiac pump function over time and is often a manifestation of ischemic injury caused by myocardial infarction (MI). Post-MI, structural remodeling of the infarcted myocardium ensues. Dysregulation of
Externí odkaz:
https://doaj.org/article/d7d91f5b4887437ca11f999e8b799b86
Autor:
Henry J. Duff, Jameson A. Dundas, Daniyil A. Svystonyuk, D. Park, Guoqi Teng, Simranjit S. Pattar, Subodh Verma, Darrell D. Belke, Jason R.B. Dyck, Paul W.M. Fedak, Ryan H. Cunnington, Sean Kang, David G. Guzzardi, Jeannine D. Turnbull, Ali Fatehi Hassanabad, Lee Anne Tibbles
Publikováno v:
Canadian Journal of Cardiology. 36:543-553
Background Empagliflozin, an SGLT2 inhibitor, has shown remarkable reductions in cardiovascular mortality and heart failure admissions (EMPA-REG OUTCOME). However, the mechanism underlying the heart failure protective effects of empagliflozin remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5459201faee52fe54961c8a92e16afc4
https://doi.org/10.1016/j.cjca.2019.08.033
https://doi.org/10.1016/j.cjca.2019.08.033
Autor:
Kristina Jeon, Ali Fatehi Hassanabad, Guoqi Teng, Vishnu Vasanthan, Sean Kang, Karl T. Wagner, Paul W.M. Fedak, Simranjit S. Pattar
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 19
International Journal of Molecular Sciences, Vol 22, Iss 10768, p 10768 (2021)
Volume 22
Issue 19
International Journal of Molecular Sciences, Vol 22, Iss 10768, p 10768 (2021)
Extracellular matrix bioscaffolds can influence the cardiac microenvironment and modulate endogenous cellular mechanisms. These materials can optimize cardiac surgery for repair and reconstruction. We investigated the biocompatibility and bioinductiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b794911b7ee8d03d909c42511ad1b29b
Publikováno v:
Frontiers in Cardiovascular Medicine
Frontiers in Cardiovascular Medicine, Vol 6 (2019)
Frontiers in Cardiovascular Medicine, Vol 6 (2019)
The epicardial surface of the heart is readily accessible during cardiac surgery and presents an opportunity for therapeutic intervention for cardiac repair and regeneration. As an important anatomic niche for endogenous mechanisms of repair, targeti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b0a4d5b6c9efd01114a536dc586e7a5
https://doi.org/10.3389/fcvm.2019.00123
https://doi.org/10.3389/fcvm.2019.00123
Fibronectin (FN) polymerization is necessary for collagen matrix deposition and is a key contributor to increased abundance of cardiac myofibroblasts (MFs) after cardiac injury. We hypothesized that interfering with FN polymerization or its genetic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65a8c4aaf37edabc88b4082930af7b94
https://europepmc.org/articles/PMC6291532/
https://europepmc.org/articles/PMC6291532/
Autor:
Darrell D. Belke, Patrick Geeraert, Daniyil A. Svystonyuk, Sean Kang, David G. Guzzardi, Paul W.M. Fedak, Guoqi Teng, Simranjit S. Pattar
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 157:109-119.e2
Objectives Fluoroquinolone (FQ) antibiotics are associated with adverse aortic clinical events. We assessed human aortic myofibroblast-mediated extracellular matrix (ECM) dysregulation as a possible cellular mechanism underlying FQ-associated aortopa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d5ffa4e1dbc5a27f43d329e29f1eb07
https://doi.org/10.1016/j.jtcvs.2018.08.079
https://doi.org/10.1016/j.jtcvs.2018.08.079
Autor:
Vasanthan V; Section of Cardiac Surgery, Department of Cardiac Sciences, Libin Cardiovascular Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada., Fatehi Hassanabad A; Section of Cardiac Surgery, Department of Cardiac Sciences, Libin Cardiovascular Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada., Pattar S; Section of Cardiac Surgery, Department of Cardiac Sciences, Libin Cardiovascular Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada., Niklewski P; MDP Solutions, Cincinnati, OH, United States.; Department of Pharmacology & Systems Physiology, College of Medicine, University of Cincinnati, Cincinnati, OH, United States.; Health Economics and Clinical Outcomes Research, Xavier University, Cincinnati, OH, United States., Wagner K; Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, ON, Canada.; Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, ON, Canada., Fedak PWM; Section of Cardiac Surgery, Department of Cardiac Sciences, Libin Cardiovascular Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Publikováno v:
Frontiers in bioengineering and biotechnology [Front Bioeng Biotechnol] 2020 Apr 17; Vol. 8, pp. 291. Date of Electronic Publication: 2020 Apr 17 (Print Publication: 2020).