Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Simran, Kaushal"'
Autor:
Aoli Xiong, Simran Kaushal, Ian Junjie Tay, Bevin P. Engelward, Jongyoon Han, Peter R. Preiser
Publikováno v:
STAR Protocols, Vol 2, Iss 3, Pp 100797- (2021)
Summary: Comet assay is a standard approach for studying DNA damage in malaria, but high-throughput options are not available. The CometChip was previously developed using mammalian cells as a high-throughput version of the comet assay. It is based o
Externí odkaz:
https://doaj.org/article/0a6b0d38982740a2bba334d1bd35f6eb
Publikováno v:
Journal of Radioanalytical and Nuclear Chemistry.
A unique UV-Curing method is provided for decontamination of radioisotopes on the surfaces which has radiation dealing facilities. In this method acrylic UV-Curing resin was poured on a contaminated simulated surface followed by UV irradiation. The r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1eff6cf186bfcdb19fe981c2862f58a8
https://doi.org/10.1007/s10967-023-08944-y
https://doi.org/10.1007/s10967-023-08944-y
Autor:
Bevin P. Engelward, Isaac A. Chaim, Patrizia Mazzucato, Catherine Ricciardi, Zachary D. Nagel, Leona D. Samson, Simran Kaushal, Le P. Ngo
Publikováno v:
Free Radic Biol Med
Although DNA repair is known to impact susceptibility to cancer and other diseases, relatively few population studies have been performed to evaluate DNA repair kinetics in people due to the difficulty of assessing DNA repair in a high throughput man
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5665e6ed1db86689e41cd947316ef6a
https://doi.org/10.1016/j.freeradbiomed.2021.07.033
https://doi.org/10.1016/j.freeradbiomed.2021.07.033
Autor:
Norah A, Owiti, Simran, Kaushal, Lincoln, Martin, Jamie, Sly, Carol D, Swartz, Jasmine, Fowler, Joshua J, Corrigan, Les, Recio, Bevin P, Engelward
Publikováno v:
Current Protocols. 2
Exposure to DNA damaging agents can lead to mutations that cause cancer. The liver is particularly vulnerable because it contains high levels of Cytochrome P450 enzymes that can convert xenobiotics into DNA reactive metabolites that form potentially
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6231d6520e79c91b248c4f32698cdaa9
https://doi.org/10.1002/cpz1.563
https://doi.org/10.1002/cpz1.563
The facilities dealing with radiation technology face the brunt of Radioactive decontamination. A unique UV-Curing method is provided for decontamination of radioisotopes on the surfaces which has radiation dealing facilities. In this method acrylic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdcd2396ba4a5b798b784bde59f18d8d
https://doi.org/10.21203/rs.3.rs-1977957/v1
https://doi.org/10.21203/rs.3.rs-1977957/v1
Autor:
Amy I.H. Hrdina, Ishwar N. Kohale, Simran Kaushal, Jamie Kelly, Noelle E. Selin, Bevin P. Engelward, Jesse H. Kroll
Publikováno v:
Environmental health perspectives. 130(2)
Polycyclic aromatic hydrocarbons (PAHs) emitted from combustion sources are known to be mutagenic, with more potent species also being carcinogenic. Previous studies show that PAHs can undergo complex transformations both in the body and in the atmos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8efdb1730674e63bb5ba403a2626ca89
https://pubmed.ncbi.nlm.nih.gov/35225689
https://pubmed.ncbi.nlm.nih.gov/35225689
Autor:
Robert W. Sobol, Jessica Fessler, Jennifer E. Kay, Bevin P. Engelward, Leona D. Samson, David M. Weingeist, Scott R. Floyd, Jing Ge, Simran Kaushal, Le P. Ngo, Danielle N. Chow, Ian J. Tay, Elina Thadhani, Patrizia Mazzucato
Publikováno v:
DNA Repair (Amst)
PMC
PMC
DNA damage can be cytotoxic and mutagenic and is directly linked to aging, cancer, and heritable diseases. To counteract the deleterious effects of DNA damage, cells have evolved highly conserved DNA repair pathways. Many commonly used DNA repair ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40c22e5465ea93b89c56b63031c6dff7
https://pubmed.ncbi.nlm.nih.gov/34365116
https://pubmed.ncbi.nlm.nih.gov/34365116
Autor:
Sergei M. Mirkin, Simran Kaushal, Jorge Cebrian, Catherine H. Freudenreich, Mayurika Lahiri, Lionel Gellon
Publikováno v:
Nucleic Acids Research
Fork stabilization at DNA impediments is key to maintaining replication fork integrity and preventing chromosome breaks. Mrc1 and Tof1 are two known stabilizers that travel with the replication fork. In addition to a structural role, Mrc1 has a DNA d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d660e29d7fdc6a71499b1670f1e72bc
https://doi.org/10.1093/nar/gky1195
https://doi.org/10.1093/nar/gky1195
Autor:
Simran Kaushal, Alice Haouzi, Catherine H. Freudenreich, Samantha B. Regan, Ryan P. Barnes, Soo Mi Lee, Suzanne E. Hile, Kohal Das, Kristin A. Eckert, Charles E. Wollmuth, Nealia C.M. House, Michael Guyumdzhyan
Publikováno v:
SSRN Electronic Journal.
Summary Common fragile sites (CFSs) are genomic regions that display gaps and breaks in human metaphase chromosomes under replication stress and are often deleted in cancer cells. We studied an ∼300-bp subregion (Flex1) of human CFS FRA16D in yeast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0330f6ddff209dbcc843e03f4f41435
https://doi.org/10.2139/ssrn.3335777
https://doi.org/10.2139/ssrn.3335777
Publikováno v:
Genes Chromosomes Cancer
Alternative non-B form DNA structures, also called secondary structures, can form in certain DNA sequences under conditions that produce single-stranded DNA, such as during replication, transcription, and repair. Direct links between secondary struct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::554e1ce10067885567b0a26b9abe2a2b
https://pubmed.ncbi.nlm.nih.gov/30536896
https://pubmed.ncbi.nlm.nih.gov/30536896